This line is available in Bloomington for purchase (follow "available" link below)
This line was part of the 205 lines genotyped using WGS, so GWAS studies can be applied to this fly.

DGRP_397 line

27 studies describing this DGRP line

Reference Phenotypes Categories Status Publication date Submitted by
Arya et al., 2010
Natural Variation, Functional Pleiotropy and Transcriptional Contexts of Odorant Binding Protein Genes in Drosophila melanogaster
[10.1534/genetics.110.123166][FBrf0212597]
mn_Longevity mn_RespAcetophen_3_5 mn_RespBenzaldeh_3_5 mn_RespHexanol_0_3 mn_RespHexanol_3_5 Ageing Olfactory Sensory Life history traits Behaviour
Curated
2010-11-30 Roel Bevers
He et al., 2016
Epistatic partners of neurogenic genes modulate Drosophila olfactory behavior
[10.1111/gbb.12279][FBrf0230854]
Canton S(B)/DGRP Sema-5cBG2386/DGRP neurBG2391/DGRP Behaviour
Under curation
2016-01-31 romain.rochepeau
Shorter et al., 2015
Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior
[10.1073/pnas.1510104112][FBrf0228967]
mn_AggressionScore Behaviour
Curated
2015-07-06 Roel Bevers
Morozova et al., 2015
Polymorphisms in early neurodevelopmental genes affect natural variation in alcohol sensitivity in adult drosophila
[10.1186/s12864-015-2064-5][FBrf0229987]
mn_AlcoholSens_E1 mn_AlcoholSens_E2 mn_AlcoholTolerance se_AlcoholSens_E1 se_AlcoholSens_E2 se_AlcoholTolerance Metabolism Resistance Toxicity
Curated
2015-11-30 Roel Bevers
Wang et al., 2017
The genetic basis for variation in resistance to infection in the Drosophila melanogaster genetic reference panel
[10.1371/journal.ppat.1006260][FBrf0235068]
LT50_Metarhizium_Ani LT50_Pseudomonas_Aer Resistance Immunity
Curated
2017-03-02 Roel Bevers
Battlay et al., 2016
Genomic and Transcriptomic Associations Identify a New Insecticide Resistance Phenotype for the Selective Sweep at the Cyp6g1 Locus of Drosophila melanogaster
[10.1534/g3.116.031054][FBrf0233124]
LD50_Azinphos_Methyl mn_Surv_Azinpho_0_25 mn_Surv_Azinpho_0_5 mn_Surv_Azinpho_1_0 mn_Surv_Azinpho_2_0 Resistance Toxicity Metabolism
Curated
2016-07-31 Roel Bevers
Hoffman et al., 2021
Sex, mating and repeatability of Drosophila melanogaster longevity
[10.1098/rsos.210273][FBrf0250359]
Age Age_hours Cohort Deaths Interaction_Estimate Interaction_p_value MatingEstim_VirginEf Mating_Status Mating_p_value Mating_status Sex_Estimate_M Sex_p_value md_Longevity_Mated md_Longevity_Virgin mn_Longevity_Mated mn_Longevity_Virgin Ageing Life history traits
Under curation
2021-07-31 romain.rochepeau
Riddle, 2020
Variation in the response to exercise stimulation in Drosophila: marathon runner versus sprinter genotypes
[10.1242/jeb.229997][FBrf0246800]
EarlyAct Late_Activity PercentEarly Vial VialNumber Behaviour
Under curation
2019-12-31 romain.rochepeau
Davis et al., 2021
Characterizing dopaminergic neuron vulnerability using genome-wide analysis
[10.1093/genetics/iyab081][FBrf0252031]
AVG PPL1 neurons Behaviour
Under curation
2021-08-08 romain.rochepeau
Duneau et al., 2018
Signatures of insecticide selection in the genome of Drosophila melanogaster
[10.1101/287250]
Delta_Alive.at.48h Experience 1 Delta_Alive.at.48h Experience 2 Delta_Alive.at.48h Experience 3 Delta_Alive.at.48h Experience 4 Delta_Alive.at.48h Experience 5 Delta_Death.at.48h Experience 1 Delta_Death.at.48h Experience 2 Delta_Death.at.48h Experience 3 Delta_Death.at.48h Experience 4 Delta_Death.at.48h Experience 5 Sample.size Experience 1 Sample.size Experience 2 Sample.size Experience 3 Sample.size Experience 4 Sample.size Experience 5 Resistance
Under curation
2018-03-22 romain.rochepeau
Watanabe et al., 2018
Genetic networks underlying natural variation in basal and induced activity levels in Drosophila melanogaster
[10.1101/444380]
ActivityTotal_2hrs Activity_5min Treatment Behaviour
Under curation
2018-10-15 romain.rochepeau
Harrison et al., 2020
The metabolome as a link in the genotype-phenotype map for peroxide resistance in the fruit fly, Drosophila melanogaster
[10.1186/s12864-020-6739-1][FBrf0245603]
300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 Carried Censored Deaths Flag1 Flag2 N NWMRC_Block Treatment Wavelength alive consumed food lifespan line.weight number.of.flies time.on.dye time.without.dye treatment Resistance Metabolism
Under curation
2020-11-30 romain.rochepeau
Chi et al., 2021
RNA-binding protein syncrip regulates starvation-induced hyperactivity in adult Drosophila
[10.1371/journal.pgen.1009396][FBrf0248324]
Baseline_mean Baseline_sem DA_mean DA_sem Starvation Resistance Behaviour
Under curation
2021-02-21 romain.rochepeau
Zhou et al., 2016
The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster
[10.1289/ehp.1510513][FBrf0233045]
gp_Dev_Time_Lead gp_Viability_Lead mn_Dev_Time mn_Dev_Time_Lead mn_Tot_Activity mn_Tot_Activity_Lead mn_Viability mn_Viability_Lead Toxicity Life history traits
Curated
2016-06-30 Roel Bevers
Morgante et al., 2015
Genetic Architecture of Micro-Environmental Plasticity in Drosophila melanogaster
[10.1038/srep09785][FBrf0228381]
ChillComaRec StartleRes StarvationRes sd_ChillComaRec sd_StartleRes sd_StarvationRes se_ChillComaRec se_StartleRes se_StarvationRes Resistance Behaviour Locomotion
Curated
2015-09-21 Roel Bevers
Campbell et al., 2019
Genome-Wide Association Analysis of Anoxia Tolerance in Drosophila melanogaster
[10.1534/g3.119.400421][FBrf0243370]
Mean SE Variance Resistance
Under curation
2019-08-31 romain.rochepeau
Garlapow et al., 2015
Quantitative Genetics of Food Intake in Drosophila melanogaster
[10.1371/journal.pone.0138129][FBrf0229641]
Food_Intake Metabolism Nutrition Behaviour
Curated
2015-09-15 Roel Bevers
Spierer et al., 2021
Natural variation in the regulation of neurodevelopmental genes modifies flight performance in Drosophila
[10.1371/journal.pgen.1008887][FBrf0248437]
Flight phenotype score Behaviour
Under curation
2021-03-17 romain.rochepeau
Ørsted et al., 2017
Environmental variation partitioned into separate heritable components
[10.1111/evo.13391][FBrf0237717]
CTmin 23C Mean CTmin 23C SE Inversion_2L_t Inversion_2R_NS Inversion_3R_K Inversion_3R_Mo Inversion_3R_P V.AE Mean V.AE SE V.WE Mean V.WE SE V.plast Mean V.plast SE V.v.plast Mean V.v.plast SE WolbachiaStatus grp Resistance Genome architecture
Under curation
2017-12-31 romain.rochepeau
Lafuente et al., 2018
Genetic basis of thermal plasticity variation in Drosophila melanogasterbody size
[10.1101/268201]
Body part Length (mm) Temperature Appearance
Under curation
2018-03-06 romain.rochepeau
Patel et al., 2021
Identification of genetic modifiers of lifespan on a high sugar diet in the Drosophila Genetic Reference Panel
[10.1016/j.heliyon.2021.e07153][FBrf0249297]
Average Lifespan Life history traits
Under curation
2021-05-31 romain.rochepeau
Wang et al., 2020
Genetic variation for resistance to the specific fly pathogen Entomophthora muscae
[10.1038/s41598-020-71262-w][FBrf0246635]
Em Average % Mortality at Day 5 Em Rank Life Time Fecundity s (Durham et al 2014) Lifespan s (Durham et al 2014) MSB Resistance (Weber et al 2012) Ma549 LT50 (Wang et al 2017) Ma549 LT50 Rank Negative Geotaxis (Jordan et al 2012) Night Bout Number (Harbison et al 2014) Night Sleep Duration (Harbison et al 2014) Pa14 LT50 (Wang et al 2017) Pa14 LT50 Rank Paraquat Resistance (Weber et al 2012) Startle Response (Jordan et al 2012) Starvation Resistance (Mackay et al 2012) Wolbachia Infection Status (Mackay et al 2012) Resistance Immunity
Under curation
2020-11-30 romain.rochepeau
Evangelou et al., 2018
Unpredictable effects of the genetic background of transgenic lines in physiological quantitative traits
[10.1101/494419]
Branching_O2_5pc Fecal_PH_PAeruginosa Fecundity Survival_Paeruginosa midgut_mitosis_PA pc_Defecation_Paerug Metabolism Life history traits
Under curation
2018-12-12 romain.rochepeau
Rohde et al., 2018
Functional Validation of Candidate Genes Detected by Genomic Feature Models
[10.1534/g3.118.200082][FBrf0238818]
Mean Behaviour
Under curation
2018-04-30 romain.rochepeau
Rohde et al., 2019
Genetic Signatures of Drug Response Variability in Drosophila melanogaster
[10.1534/genetics.119.302381][FBrf0243724]
Food_Intake_MPH Food_Intake_SUC Locomot_Activity_MPH Locomot_Activity_SUC Locomotion Behaviour
Curated
2019-09-30 romain.rochepeau
Bonfini et al., 2021
Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size
[10.7554/elife.64125]
Gut_Number additional_code alias anteriorLength anteriorwidth block code diet image middleLength posteriorLength posteriorwidth totalLength Development Organ Size Metabolism
Under curation
2021-09-22 romain.rochepeau
Huang et al., 2014
Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines
[10.1101/gr.171546.113][FBrf0225536]
Inversion_2L_t Inversion_2R_NS Inversion_2R_Y1 Inversion_2R_Y2 Inversion_2R_Y3 Inversion_2R_Y4 Inversion_2R_Y5 Inversion_2R_Y6 Inversion_2R_Y7 Inversion_3L_M Inversion_3L_P Inversion_3L_Y Inversion_3R_C Inversion_3R_K Inversion_3R_Mo Inversion_3R_P SegregVariants_2L SegregVariants_2R SegregVariants_3L SegregVariants_3R SegregVariants_X TotalVariants_2L TotalVariants_2R TotalVariants_3L TotalVariants_3R TotalVariants_X WolbachiaStatus mn_GenomeSize pc_SegregVariants_2L pc_SegregVariants_2R pc_SegregVariants_3L pc_SegregVariants_3R pc_SegregVariants_X se_GenomeSize Genome architecture Microbiota
Curated
2014-06-30 Roel Bevers

152 phenotypes associated

AVG PPL1 neurons ActivityTotal_2hrs Activity_5min Age Age_hours Average Lifespan Baseline_mean Baseline_sem Body part Canton S(B)/DGRP Carried Censored Cohort DA_mean DA_sem Deaths Delta_Alive.at.48h Experience 1 Delta_Alive.at.48h Experience 2 Delta_Alive.at.48h Experience 3 Delta_Alive.at.48h Experience 4 Delta_Alive.at.48h Experience 5 Delta_Death.at.48h Experience 1 Delta_Death.at.48h Experience 2 Delta_Death.at.48h Experience 3 Delta_Death.at.48h Experience 4 Delta_Death.at.48h Experience 5 EarlyAct Em Average % Mortality at Day 5 Em Rank Flag1 Flag2 Flight phenotype score Food_Intake Food_Intake_MPH Food_Intake_SUC Gut_Number Interaction_Estimate Interaction_p_value Inversion_2L_t Inversion_2L_t Inversion_2R_NS Inversion_2R_NS Inversion_2R_Y1 Inversion_2R_Y2 Inversion_2R_Y3 Inversion_2R_Y4 Inversion_2R_Y5 Inversion_2R_Y6 Inversion_2R_Y7 Inversion_3L_M Inversion_3L_P Inversion_3L_Y Inversion_3R_C Inversion_3R_K Inversion_3R_K Inversion_3R_Mo Inversion_3R_Mo Inversion_3R_P Inversion_3R_P LD50_Azinphos_Methyl LT50_Metarhizium_Ani LT50_Pseudomonas_Aer Late_Activity Length (mm) Locomot_Activity_MPH Locomot_Activity_SUC Ma549 LT50 (Wang et al 2017) Ma549 LT50 Rank MatingEstim_VirginEf Mating_Status Mating_p_value Mating_status Mean N Pa14 LT50 (Wang et al 2017) Pa14 LT50 Rank PercentEarly SE Sample.size Experience 1 Sample.size Experience 2 Sample.size Experience 3 Sample.size Experience 4 Sample.size Experience 5 SegregVariants_2L SegregVariants_2R SegregVariants_3L SegregVariants_3R SegregVariants_X Sema-5cBG2386/DGRP Sex_Estimate_M Sex_p_value StartleRes Starvation Resistance Starvation Resistance (Mackay et al 2012) StarvationRes Temperature TotalVariants_2L TotalVariants_2R TotalVariants_3L TotalVariants_3R TotalVariants_X Variance VialNumber Wolbachia Infection Status (Mackay et al 2012) WolbachiaStatus WolbachiaStatus additional_code alias anteriorLength anteriorwidth block code diet gp_Dev_Time_Lead gp_Viability_Lead grp md_Longevity_Mated md_Longevity_Virgin middleLength mn_AggressionScore mn_AlcoholSens_E1 mn_AlcoholSens_E2 mn_AlcoholTolerance mn_GenomeSize mn_Longevity mn_Longevity_Mated mn_Longevity_Virgin mn_RespAcetophen_3_5 mn_RespBenzaldeh_3_5 mn_RespHexanol_0_3 mn_RespHexanol_3_5 mn_Surv_Azinpho_0_25 mn_Surv_Azinpho_0_5 mn_Surv_Azinpho_1_0 mn_Surv_Azinpho_2_0 neurBG2391/DGRP pc_SegregVariants_2L pc_SegregVariants_2R pc_SegregVariants_3L pc_SegregVariants_3R pc_SegregVariants_X posteriorLength posteriorwidth sd_StartleRes sd_StarvationRes se_AlcoholSens_E1 se_AlcoholSens_E2 se_AlcoholTolerance se_GenomeSize se_StartleRes se_StarvationRes totalLength