Study

Curated
Dobson et al., 2015
Host genetic determinants of microbiota-dependent nutrition revealed by genome-wide analysis of Drosophila melanogaster
[10.1038/ncomms7312]

Description

This study examined the genetic basis for how gut microbiota affect five nutritional traits (weight, protein, lipid, glucose, and glycogen contents) in fruit flies. The authors found significant genotype-dependent variations in these traits when the microbiota were eliminated, identifying specific genetic polymorphisms associated with these variations and validating key genes involved in these microbiota-dependent nutritional effects. Additionally, they observed that the presence of the intracellular bacterium Wolbachia influenced glycogen content, with Wolbachia-positive lines showing higher glycogen levels compared to Wolbachia-free lines.

Comments from curator

Despite being a study about microbiota-dependent nutrition, we could not find any other phenotypes than the Wolbachia Status in this study?

Phenotyping data is available from Supp Table S6 in supplementary data section.

3 categories

Microbiota Metabolism Nutrition

1 phenotype

WolbachiaStatus
Back to studies