Chow et al., 2013
Large Neurological Component to Genetic Differences Underlying Biased Sperm Use in Drosophila
[10.1534/genetics.112.146357][FBrf0220325]

Description

This study examines the female factors (and genes) that mediate sperm competition outcomes. Females were tested in double-mating trials, and the amount of progeny was accounted for, especially distinguishing progeny coming from the first vs the second mating (by eye color). One of the lines never engaged in a second mating. Further knockdown studies of three candidate genes (para, Rab2, and Rim) in sensory neurons indicate that sperm competition may be affected by the neural input innervating the female reproductive tract.

Comments from curator

Phenotyping data were extracted from Table S1 in genetics.112.146357-1 pdf file from the Supplementary data section

Gene expression data was used from FlyAtlas (Chintapalli et al. 2007)

The provided data are summary data (means, sd, cv, ...) across multiple flies from the same DGRP line. The raw data per fly is not available, so we cannot reproduce Fig.1 or Fig. S1b for e.g.

39 DGRP lines 1 not_genotyped 38 genotyped

DGRP_208 DGRP_301 DGRP_303 DGRP_304 DGRP_306 DGRP_307 DGRP_313 DGRP_315 DGRP_324 DGRP_335 DGRP_357 DGRP_358 DGRP_360 DGRP_362 DGRP_365 DGRP_375 DGRP_379 DGRP_380 DGRP_391 DGRP_399 DGRP_427 DGRP_437 DGRP_486 DGRP_514 DGRP_517 DGRP_555 DGRP_639 DGRP_705 DGRP_707 DGRP_712 DGRP_714 DGRP_730 DGRP_732 DGRP_765 DGRP_774 DGRP_786 DGRP_799 DGRP_820 DGRP_852

Datasets

Dataset	Phenotypes	DGRP lines
Summary dataset	3 phenotypes Progeny_Total pc_Progeny_P1 pc_Remating_Female	39 DGRP lines DGRP_208 DGRP_301 DGRP_303 DGRP_304 DGRP_306 DGRP_307 DGRP_313 DGRP_315 DGRP_324 DGRP_335 DGRP_357 DGRP_358 DGRP_360 DGRP_362 DGRP_365 DGRP_375 DGRP_379 DGRP_380 DGRP_391 DGRP_399 DGRP_427 DGRP_437 DGRP_486 DGRP_514 DGRP_517 DGRP_555 DGRP_639 DGRP_705 DGRP_707 DGRP_712 DGRP_714 DGRP_730 DGRP_732 DGRP_765 DGRP_774 DGRP_786 DGRP_799 DGRP_820 DGRP_852	Download