©2022-2026 Deplancke lab, EPFL, 1015 Lausanne
Life history traits refer to the numerous different aspects shaping the <i>Drosophila</i> existence. These traits include growth rate; age and size at sexual maturity; the temporal pattern or schedule of reproduction; the number, size, and sex ratio of offspring; the distribution of intrinsic or extrinsic mortality rates (e.g., patterns of senescence); and patterns of dormancy and dispersal.
| Reference | Status | Publication date | Submitted by | |
|---|---|---|---|---|
| Durham et al., 2014 Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits [10.1038/ncomms5338][FBrf0225589] |
Curated |
2014-08-31 | Roel Bevers | |
| Zhou et al., 2016 The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster [10.1289/ehp.1510513][FBrf0233045] |
Curated |
2016-06-30 | Roel Bevers | |
| Harbison et al., 2018 Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster [10.1007/s10519-018-9932-0][FBrf0241121] |
Curated |
2018-12-31 | Roel Bevers | |
| Jordan et al., 2012 Genome-Wide Association for Sensitivity to Chronic Oxidative Stress in Drosophila melanogaster [10.1371/journal.pone.0038722][FBrf0218606] |
Curated |
2012-06-07 | Roel Bevers | |
| Unckless et al., 2015 A Genome-Wide Association Study for Nutritional Indices in Drosophila [10.1534/g3.114.016477][FBrf0227710] |
Curated |
2015-02-28 | Roel Bevers | |
| Chen et al., 2019 Female Genetic Contributions to Sperm Competition in Drosophila melanogaster [10.1534/genetics.119.302284] |
Rejected |
2019-07-01 | romain.rochepeau | |
| Rodrigues et al., 2022 The genetic basis and adult reproductive consequences of developmental thermal plasticity [10.1111/1365-2656.13664][FBrf0253732] |
Curated |
2022-05-31 | romain.rochepeau | |
| Huang et al., 2020 Context-dependent genetic architecture of Drosophila life span [10.1371/journal.pbio.3000645][FBrf0245198] |
Curated |
2020-03-04 | Roel Bevers | |
| Akhund-Zade et al., 2021 Genetic basis of offspring number–body weight tradeoff in Drosophila melanogaster [10.1093/g3journal/jkab129] |
Curated |
2021-07-13 | romain.rochepeau | |
| McCracken et al., 2020 The hidden costs of dietary restriction: Implications for its evolutionary and mechanistic origins [10.1126/sciadv.aay3047] |
Curated |
2020-02-21 | romain.rochepeau | |
| Knudsen et al., 2020 Genetic Variation and Potential for Resistance Development to the tTA Overexpression Lethal System in Insects [10.1534/g3.120.400990][FBrf0245357] |
Curated |
2020-03-31 | romain.rochepeau | |
| McCracken et al., 2020 The relationship between longevity and diet is genotype dependent and sensitive to desiccation in Drosophila melanogaster [10.1242/jeb.230185][FBrf0247456] |
Curated |
2019-12-31 | romain.rochepeau | |
| Wilson et al., 2020 GWAS for Lifespan and Decline in Climbing Ability in Flies upon Dietary Restriction Reveal decima as a Mediator of Insulin-like Peptide Production [10.1016/j.cub.2020.05.020][FBrf0246266] |
Curated |
2020-06-30 | romain.rochepeau | |
| Hall et al., 2019 Identification of novel genes associated with longevity in Drosophila melanogaster - a computational approach [10.18632/aging.102527][FBrf0244333] |
Rejected |
2019-12-14 | romain.rochepeau | |
| Siva-Jothy et al., 2021 Dissecting genetic and sex-specific sources of host heterogeneity in pathogen shedding and spread [10.1371/journal.ppat.1009196][FBrf0247956] |
Curated |
2021-01-18 | romain.rochepeau | |
| Savola et al., 2021 Testing evolutionary explanations for the lifespan benefit of dietary restriction in fruit flies (Drosophila melanogaster) [10.1111/evo.14146][FBrf0248261] |
Rejected |
2021-01-31 | romain.rochepeau | |
| Masson et al., 2020 Blind killing of both male and female Drosophila embryos by a natural variant of the endosymbiotic bacterium Spiroplasma poulsonii [10.1111/cmi.13156][FBrf0245270] |
Rejected |
2020-04-30 | romain.rochepeau | |
| Schiffman et al., 2020 Ageing and genetic background influence anaesthetic effects in a D. melanogaster model of blunt trauma with brain injury [10.1016/j.bja.2020.03.029][FBrf0245944] |
Under curation |
2020-06-30 | romain.rochepeau | |
| Carbone et al., 2016 Genetic architecture of natural variation in visual senescence in Drosophila [10.1073/pnas.1613833113][FBrf0233864] |
Curated |
2016-10-24 | Roel Bevers | |
| Hoffman et al., 2021 Sex, mating and repeatability of Drosophila melanogaster longevity [10.1098/rsos.210273][FBrf0250359] |
Curated |
2021-07-31 | romain.rochepeau | |
| Katzenberger et al., 2015 Death following traumatic brain injury in Drosophila is associated with intestinal barrier dysfunction [10.7554/eLife.04790][FBrf0227948] |
Curated |
2015-03-04 | Roel Bevers | |
| Huang et al., 2012 Epistasis dominates the genetic architecture of Drosophila quantitative traits [10.1073/pnas.1213423109][FBrf0219551] |
Rejected |
2012-09-24 | romain.rochepeau | |
| Jin et al., 2020 Genetic and metabolomic architecture of variation in diet restriction-mediated lifespan extension in Drosophila [10.1371/journal.pgen.1008835][FBrf0246151] |
Curated |
2020-07-08 | romain.rochepeau | |
| Arya et al., 2010 Natural Variation, Functional Pleiotropy and Transcriptional Contexts of Odorant Binding Protein Genes in Drosophila melanogaster [10.1534/genetics.110.123166][FBrf0212597] |
Curated |
2010-11-30 | Roel Bevers | |
| Chow et al., 2013 Large Neurological Component to Genetic Differences Underlying Biased Sperm Use in Drosophila [10.1534/genetics.112.146357][FBrf0220325] |
Curated |
2012-12-31 | Roel Bevers | |
| Dean et al., 2018 Masculinization of gene expression is associated with male quality in Drosophila melanogaster [10.1111/evo.13618][FBrf0240924] |
Curated |
2018-11-30 | romain.rochepeau | |
| Gabrawy et al., 2019 Lisinopril Preserves Physical Resilience and Extends Life Span in a Genotype-Specific Manner in Drosophila melanogaster [10.1093/gerona/glz152][FBrf0244035] |
Curated |
2019-11-12 | romain.rochepeau | |
| Zhao et al., 2022 The metabolome as a biomarker of aging in Drosophila melanogaster [10.1111/acel.13548][FBrf0252669] |
Curated |
2022-01-31 | romain.rochepeau | |
| Patel et al., 2021 Identification of genetic modifiers of lifespan on a high sugar diet in the Drosophila Genetic Reference Panel [10.1016/j.heliyon.2021.e07153][FBrf0249297] |
Curated |
2021-05-31 | romain.rochepeau | |
| Chow et al., 2013 Using natural variation in Drosophila to discover previously unknown endoplasmic reticulum stress genes [10.1073/pnas.1307125110][FBrf0221713] |
Curated |
2013-05-27 | Roel Bevers | |
| Rohde et al., 2021 Genotype and Trait Specific Responses to Rapamycin Intake in Drosophila melanogaster [10.3390/insects12050474][FBrf0249203] |
Curated |
2021-05-19 | romain.rochepeau | |
| Evangelou et al., 2019 Unpredictable Effects of the Genetic Background of Transgenic Lines in Physiological Quantitative Traits [10.1534/g3.119.400715] |
Curated |
2019-11-01 | romain.rochepeau | |
| Watanabe et al., 2021 Exercise-induced changes in climbing performance [10.1098/rsos.211275][FBrf0251956] |
Curated |
2021-10-31 | romain.rochepeau | |
| Havula et al., 2022 Genetic variation of macronutrient tolerance in Drosophila melanogaster [10.1038/s41467-022-29183-x] |
Curated |
2022-03-28 | tahlia.fulton | |
| Bak et al., 2025 The role of genetic variation in shaping phenotypic responses to diet in aging Drosophila melanogaster [10.1038/s41437-025-00797-3] |
Curated |
2025-11-01 | tahlia.fulton | |
| Morozova et al., 2018 A Cyclin E Centered Genetic Network Contributes to Alcohol-Induced Variation in Drosophila Development [10.1534/g3.118.200260][FBrf0239702] |
Curated |
2018-07-31 | romain.rochepeau | |
| Ayroles et al., 2009 Systems genetics of complex traits in Drosophila melanogaster [10.1038/ng.332] |
Under curation |
2009-02-28 | romain.rochepeau | |
| Horváth et al., 2016 A novel method for quantifying the rate of embryogenesis uncovers considerable genetic variation for the duration of embryonic development in Drosophila melanogaster [10.1186/s12862-016-0776-z][FBrf0233634] |
Curated |
2016-11-30 | romain.rochepeau | |
| Patlar et al., 2023 A predominant role of genotypic variation in both expression of sperm competition genes and paternity success in Drosophila melanogaster [10.1098/rspb.2023.1715] |
Curated |
2023-09-26 | Anonymous | |
| Wong et al., 2023 Pleiotropic fitness effects across sexes and ages in the Drosophila genome and transcriptome [10.1093/evolut/qpad163] |
Curated |
2023-09-19 | Anonymous | |
| Cannavò et al., 2016 Genetic variants regulating expression levels and isoform diversity during embryogenesis [10.1038/nature20802] |
Curated |
2016-12-31 | Anonymous | |
| Brown et al., 2020 Behavioral and Transcriptional Response to Selection for Olfactory Behavior in Drosophila [10.1534/g3.120.401117][FBrf0245363] |
Rejected |
2020-03-31 | romain.rochepeau | |
| Dick et al., 2011 Genetic variation of dietary restriction and the effects of nutrient-free water and amino acid supplements on lifespan and fecundity of Drosophila [10.1017/S001667231100019X] |
Under curation |
2011-08-01 | Vincent Gardeux | |
| Duun Rohde et al., 2016 A Quantitative Genomic Approach for Analysis of Fitness and Stress Related Traits in a Drosophila melanogaster Model Population [10.1155/2016/2157494] |
Under curation |
2016-01-01 | Vincent Gardeux | |
| Horváth et al., 2016 Effects of larval crowding on quantitative variation for development time and viability in Drosophila melanogaster [10.1002/ece3.2552] |
Under curation |
2016-12-01 | Vincent Gardeux |