Comments from curator
No phenotype data are available for this study.The authors measured six organismal traits on 40 wild-derived inbred lines from Raleigh, NC, which later became part of the DGRP:
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Starvation stress resistance: survival of 10 same-sex 2-day-old flies per vial on 1.5% agar, scored every 8 hours (5 vials per sex and line).
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Chill coma recovery time: time for each 3-7-day-old fly to right itself after 3 hours on ice (20 flies per sex and line).
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Life span: 5 same-sex virgin flies per vial, survival scored every 2 days (5 vials per sex and line).
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Locomotor reactivity: total activity of single 3-7-day-old flies in the 45 s following a mechanical disturbance (2 replicates of 20 flies per sex and line).
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Copulation latency: minutes until a pair of 3-7-day-old virgin flies started copulating, observed for at most 120 min (24 pairs per line, sexes not separated).
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Competitive fitness: competitive index against a compound-autosome tester stock, i.e. the proportion of wild-type progeny emerging by day 17 (20 vials per line, sexes not separated).
Per-line values are only shown as bar plots of the line means in Figure 4 of the
paper (
PMC version). The
supplementary information only gives variance components, heritabilities and genetic correlations for these traits (
Supplementary Table 4) and the associations of single feature polymorphisms and transcripts with them (
Supplementary Tables 5, 6 and 8).
Supplementary Table 7 is about P-element mutants, not DGRP lines. No repository is cited for the phenotype data, so per-line values could not be retrieved.
The whole-body gene expression data (Affymetrix Drosophila 2.0 arrays, 3-5-day-old males and females, 2 replicate pools of 25 flies per sex and line) are available on ArrayExpress (
E-MEXP-1594). As genome-wide expression data, they are only linked here and not integrated in DGRPool.
Of note, starvation stress resistance, chill coma recovery and startle response were measured again on the whole DGRP in
Mackay et al., 2012. These are separate measurements, not the data of this study.
