Toxicity studies

These studies are designed to detect how the genetics profile can modulate the physiological and pathological effects of a toxin, including lethality. Usually, these studies perform acute single-dose toxicity testing or dose range protocols, that include dose escalation and maximum tolerated dose studies.

7 studies contained in the category :

Reference Status Publication date Submitted by
Najarro et al., 2017
Loci Contributing to Boric Acid Toxicity in Two Reference Populations of Drosophila melanogaster
[10.1534/g3.117.041418][FBrf0235744]
Curated
 2017-05-31 Roel Bevers
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Morozova et al., 2015
Polymorphisms in early neurodevelopmental genes affect natural variation in alcohol sensitivity in adult drosophila
[10.1186/s12864-015-2064-5][FBrf0229987]
Curated
 2015-11-30 Roel Bevers
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Battlay et al., 2016
Genomic and Transcriptomic Associations Identify a New Insecticide Resistance Phenotype for the Selective Sweep at the Cyp6g1 Locus of Drosophila melanogaster
[10.1534/g3.116.031054][FBrf0233124]
Curated
 2016-07-31 Roel Bevers
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Zhou et al., 2016
The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster
[10.1289/ehp.1510513][FBrf0233045]
Curated
 2016-06-30 Roel Bevers
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Mitchell et al., 2017
α-amanitin resistance in Drosophila melanogaster: A genome-wide association approach
[10.1371/journal.pone.0173162][FBrf0234898]
Curated
 2017-02-26 Roel Bevers
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Montgomery et al., 2014
Genome-Wide Association Analysis of Tolerance to Methylmercury Toxicity in Drosophila Implicates Myogenic and Neuromuscular Developmental Pathways
[10.1371/journal.pone.0110375][FBrf0226648]
Curated
 2014-10-30 Roel Bevers
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Najarro et al., 2015
Identifying Loci Contributing to Natural Variation in Xenobiotic Resistance in Drosophila
[10.1371/journal.pgen.1005663][FBrf0230275]
Curated
 2015-11-29 Roel Bevers
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