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MosaicDiff phenotype

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Description

Difference between the observed embryo mosaicism rate and the rate expected from the full embryo resistance rate (second-order polynomial fitted by the authors over the DGRP lines, Figure S2), one value per vial. It isolates the duration of Cas9 activity from the embryo resistance rate itself and was one of the two traits used for the authors' GWAS. Can be negative. Copied from Data S2. Measured on the F1 drive/wild-type heterozygous daughters of virgin DGRP females crossed to males carrying the drive (nanos-Cas9, 3xP3-dsRed, w1118 background), by scoring the progeny of those F1 flies; the value is assigned to the DGRP line. [No unit]

Defined in study
Champer et al., 2019
CRISPR Gene Drive Efficiency and Resistance Rate Is Highly Heritable with No Common Genetic Loci of Large Effect
[10.1534/genetics.119.302037][FBrf0242214]
Values
Number of mean values for undefined sex: 138
Number of mean unique values for undefined sex: 138
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