DGRPool

GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=8.771e^-1)
Null hypothesis is not rejected (p>0.05).
Interpretation: NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test

Covariate	p-value	Significance
In_3R_K	0.02011

Kruskal-Wallis test

Covariate	χ²	p-value	Significance
In_3R_K	4.1938	0.0406

PNG PDF

QQplot

PNG PDF

Manhattan plot

GWAS results

1372 significant hits at p-value < 0.001. The 1000 top results are displayed in the table below.

We performed a gene enrichment calculation (Fisher's exact test) of all GWAS-associated genes at p < 0.001. Genesets were taken from two database: the Gene Ontology (GO) and the FlyBase phenotypes. GO enrichment FlyBase phenotype enrichment

Variant impact HIGH MODERATE LOW MODIFIER

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Chromosome	Position	ID	Reference	Variant	p-value	FDR_BH	Transcript annotation	Binding site annotation
2R	1756321	2R_1756321_DEL [dm3] 2R_5868816_DEL [dm6]	TAGAATATTTATTCTTGATC...	T	7.178e^-7	0.467	INTERGENIC
2L	11486035	2L_11486035_SNP [dm3] 2L_11486035_SNP [dm6]	G	C	8.191e^-7	0.467	UPSTREAM sala DOWNSTREAM CG43355 INTRON CG43355 & 1 other	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
2L	11485934	2L_11485934_SNP [dm3] 2L_11485934_SNP [dm6]	C	T	1.057e^-6	0.467	UPSTREAM sala DOWNSTREAM CG43355 INTRON CG43355 & 1 other	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
2L	11485937	2L_11485937_SNP [dm3] 2L_11485937_SNP [dm6]	T	C	1.057e^-6	0.467	UPSTREAM sala DOWNSTREAM CG43355 INTRON CG43355 & 1 other	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
2R	4727026	2R_4727026_SNP [dm3] 2R_8839521_SNP [dm6]	A	G	1.485e^-6	0.525	INTRON sns
2R	13045522	2R_13045522_SNP [dm3] 2R_17158017_SNP [dm6]	A	G	3.675e^-6	0.809	SYNONYMOUS_CODING CG17287 DOWNSTREAM CG17290 & 1 other
2L	15248135	2L_15248135_SNP [dm3] 2L_15248135_SNP [dm6]	A	T	5.441e^-6	0.809	UPSTREAM ZnT35C & 1 other INTERGENIC
2R	13044615	2R_13044615_SNP [dm3] 2R_17157110_SNP [dm6]	C	T	5.960e^-6	0.809	UTR_3_PRIME CG17290 & 1 other
2L	15248273	2L_15248273_DEL [dm3] 2L_15248273_DEL [dm6]	GCAG	G	6.134e^-6	0.809	UPSTREAM ZnT35C & 1 other INTERGENIC
2R	13002550	2R_13002550_SNP [dm3] 2R_17115045_SNP [dm6]	A	G	6.242e^-6	0.809	DOWNSTREAM CG15611 INTERGENIC
2L	15248188	2L_15248188_SNP [dm3] 2L_15248188_SNP [dm6]	A	T	6.273e^-6	0.809	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	15248211	2L_15248211_SNP [dm3] 2L_15248211_SNP [dm6]	C	T	6.550e^-6	0.809	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	15248233	2L_15248233_SNP [dm3] 2L_15248233_SNP [dm6]	G	C	6.550e^-6	0.809	UPSTREAM ZnT35C & 1 other INTERGENIC
3R	2434700	3R_2434700_SNP [dm3] 3R_6608978_SNP [dm6]	G	A	7.364e^-6	0.809	UPSTREAM glob2 INTERGENIC
2R	13044434	2R_13044434_SNP [dm3] 2R_17156929_SNP [dm6]	A	T	8.217e^-6	0.809	UTR_3_PRIME CG17290 & 1 other
3L	8413602	3L_8413602_DEL [dm3] 3L_8420502_DEL [dm6]	ATGT	A	8.309e^-6	0.809	INTRON CG32354
2L	15248161	2L_15248161_SNP [dm3] 2L_15248161_SNP [dm6]	T	A	9.160e^-6	0.809	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	15248164	2L_15248164_SNP [dm3] 2L_15248164_SNP [dm6]	G	C	9.160e^-6	0.809	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	15248172	2L_15248172_SNP [dm3] 2L_15248172_SNP [dm6]	T	A	9.160e^-6	0.809	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	15248180	2L_15248180_INS [dm3] 2L_15248180_INS [dm6]	G	GT	9.160e^-6	0.809	UPSTREAM ZnT35C & 1 other INTERGENIC
3L	10674618	3L_10674618_SNP [dm3] 3L_10681518_SNP [dm6]	T	C	1.314e^-5	0.975	INTRON simj	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_GATAe mE1_TFBS_HSA mE1_TFBS_Trl
2R	13002549	2R_13002549_SNP [dm3] 2R_17115044_SNP [dm6]	T	G	1.436e^-5	0.975	DOWNSTREAM CG15611 INTERGENIC
2R	13002552	2R_13002552_SNP [dm3] 2R_17115047_SNP [dm6]	G	A	1.436e^-5	0.975	DOWNSTREAM CG15611 INTERGENIC
2R	6739540	2R_6739540_SNP [dm3] 2R_10852035_SNP [dm6]	T	C	1.466e^-5	0.975	INTRON CG30015
3L	4970262	3L_4970262_SNP [dm3] 3L_4970262_SNP [dm6]	T	C	1.576e^-5	0.975	INTRON Con	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
2L	11486093	2L_11486093_SNP [dm3] 2L_11486093_SNP [dm6]	A	C	1.948e^-5	0.975	UTR_5_PRIME sala UTR_3_PRIME CG43355 UPSTREAM sala DOWNSTREAM CG43355	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
2R	13044562	2R_13044562_SNP [dm3] 2R_17157057_SNP [dm6]	T	G	2.006e^-5	0.975	UTR_3_PRIME CG17290 & 1 other
2R	13797553	2R_13797553_SNP [dm3] 2R_17910048_SNP [dm6]	G	A	2.191e^-5	0.975	INTRON Elk
2L	15248234	2L_15248234_SNP [dm3] 2L_15248234_SNP [dm6]	T	C	2.220e^-5	0.975	UPSTREAM ZnT35C & 1 other INTERGENIC
3L	5304768	3L_5304768_SNP [dm3] 3L_5311668_SNP [dm6]	C	T	2.234e^-5	0.975	INTERGENIC
2L	3102052	2L_3102052_SNP [dm3] 2L_3102052_SNP [dm6]	T	C	2.474e^-5	0.975	INTRON toc
2L	11485417	2L_11485417_SNP [dm3] 2L_11485417_SNP [dm6]	C	T	2.476e^-5	0.975	NON_SYNONYMOUS_CODING CG43355 UTR_5_PRIME sala UPSTREAM sala	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad
3R	11587364	3R_11587364_SNP [dm3] 3R_15761642_SNP [dm6]	G	A	2.491e^-5	0.975	INTERGENIC
2R	10774709	2R_10774709_DEL [dm3] 2R_14887204_DEL [dm6]	TCTACCCT	T	2.596e^-5	0.975	UTR_3_PRIME Cyp6a8 UPSTREAM Cyp6a21
2L	15248202	2L_15248202_SNP [dm3] 2L_15248202_SNP [dm6]	A	T	2.711e^-5	0.975	UPSTREAM ZnT35C & 1 other INTERGENIC
2R	13797555	2R_13797555_SNP [dm3] 2R_17910050_SNP [dm6]	A	G	2.820e^-5	0.975	INTRON Elk
3L	10676402	3L_10676402_SNP [dm3] 3L_10683302_SNP [dm6]	G	A	2.975e^-5	0.975	INTRON simj	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad mE1_TFBS_HSA
3L	15635536	3L_15635536_SNP [dm3] 3L_15642436_SNP [dm6]	T	A	2.991e^-5	0.975	INTRON comm3
2R	13002520	2R_13002520_SNP [dm3] 2R_17115015_SNP [dm6]	A	G	3.043e^-5	0.975	DOWNSTREAM CG15611 INTERGENIC
X	16425477	X_16425477_SNP [dm3] X_16531444_SNP [dm6]	G	A	3.047e^-5	0.975	INTRON para	TF binding site BDTNP1_TFBS_dl
2R	6740549	2R_6740549_SNP [dm3] 2R_10853044_SNP [dm6]	A	G	3.181e^-5	0.975	UPSTREAM CR45136 INTRON CG30015	TF binding site BDTNP1_TFBS_twi
3L	11187892	3L_11187892_SNP [dm3] 3L_11194792_SNP [dm6]	T	C	3.232e^-5	0.975	INTRON GlcAT-P	TF binding site BDTNP1_TFBS_twi
3L	11188004	3L_11188004_SNP [dm3] 3L_11194904_SNP [dm6]	T	C	3.232e^-5	0.975	INTRON GlcAT-P	TF binding site BDTNP1_TFBS_twi
2R	1747397	2R_1747397_SNP [dm3] 2R_5859892_SNP [dm6]	G	A	3.379e^-5	0.975	UTR_3_PRIME dpr12
2R	12852342	2R_12852342_SNP [dm3] 2R_16964837_SNP [dm6]	A	G	3.391e^-5	0.975	EXON CR44376
3L	18142950	3L_18142950_SNP [dm3] 3L_18149850_SNP [dm6]	T	C	3.532e^-5	0.975	INTRON CG7330
2L	5743381	2L_5743381_SNP [dm3] 2L_5743381_SNP [dm6]	A	G	3.560e^-5	0.975	INTRON CG11030
2L	5743383	2L_5743383_SNP [dm3] 2L_5743383_SNP [dm6]	T	G	3.560e^-5	0.975	INTRON CG11030
2L	5743385	2L_5743385_INS [dm3] 2L_5743385_INS [dm6]	T	TTATTCCC	3.560e^-5	0.975	INTRON CG11030
X	19044435	X_19044435_DEL [dm3] X_19150402_DEL [dm6]	AA	A	3.585e^-5	0.975	INTRON RhoGAP18B
2L	11486010	2L_11486010_SNP [dm3] 2L_11486010_SNP [dm6]	A	G	3.609e^-5	0.975	UPSTREAM sala DOWNSTREAM CG43355 INTRON CG43355 & 1 other	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
3L	10676607	3L_10676607_SNP [dm3] 3L_10683507_SNP [dm6]	T	C	3.669e^-5	0.975	INTRON simj	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_sens
2L	15248160	2L_15248160_SNP [dm3] 2L_15248160_SNP [dm6]	T	C	3.684e^-5	0.975	UPSTREAM ZnT35C & 1 other INTERGENIC
X	2475865	X_2475865_SNP [dm3] X_2581832_SNP [dm6]	T	C	3.778e^-5	0.975	UPSTREAM CG13759 INTRON CG13759
2R	13044470	2R_13044470_SNP [dm3] 2R_17156965_SNP [dm6]	A	C	3.820e^-5	0.975	UTR_3_PRIME CG17290 & 1 other
2L	5732839	2L_5732839_SNP [dm3] 2L_5732839_SNP [dm6]	T	C	4.090e^-5	0.975	DOWNSTREAM CG11147 INTRON CG11030
2R	1756555	2R_1756555_SNP [dm3] 2R_5869050_SNP [dm6]	A	T	4.172e^-5	0.975	INTERGENIC
2L	5743071	2L_5743071_SNP [dm3] 2L_5743071_SNP [dm6]	A	C	4.354e^-5	0.975	INTRON CG11030
2L	5743559	2L_5743559_SNP [dm3] 2L_5743559_SNP [dm6]	G	A	4.354e^-5	0.975	INTRON CG11030
3R	3996798	3R_3996798_SNP [dm3] 3R_8171076_SNP [dm6]	G	A	4.531e^-5	0.975	INTRON grn	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl mE1_TFBS_HSA mE1_TFBS_sens
2R	6435275	2R_6435275_SNP [dm3] 2R_10547770_SNP [dm6]	A	T	4.539e^-5	0.975	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi
3R	11207328	3R_11207328_SNP [dm3] 3R_15381606_SNP [dm6]	C	T	4.576e^-5	0.975	UTR_3_PRIME h-cup INTRON Rbp
2L	5265427	2L_5265427_SNP [dm3] 2L_5265427_SNP [dm6]	C	A	4.614e^-5	0.975	SYNONYMOUS_CODING Cyp4ac1 UPSTREAM Cyp4ac2 INTRON tkv	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
2R	6737616	2R_6737616_SNP [dm3] 2R_10850111_SNP [dm6]	T	C	4.708e^-5	0.975	INTRON CG30015	TF binding site BDTNP1_TFBS_dl
2R	17685916	2R_17685916_SNP [dm3] 2R_21798411_SNP [dm6]	G	A	4.752e^-5	0.975	SYNONYMOUS_CODING CG18735 DOWNSTREAM CG4386	TF binding site mE1_TFBS_chinmo mE1_TFBS_HSA
2L	973537	2L_973537_SNP [dm3] 2L_973537_SNP [dm6]	C	T	4.917e^-5	0.975	INTERGENIC
3L	11582093	3L_11582093_SNP [dm3] 3L_11588993_SNP [dm6]	T	G	5.075e^-5	0.975	UPSTREAM CG7377 INTERGENIC
3L	11187715	3L_11187715_SNP [dm3] 3L_11194615_SNP [dm6]	G	A	5.118e^-5	0.975	INTRON GlcAT-P
3R	2435982	3R_2435982_SNP [dm3] 3R_6610260_SNP [dm6]	T	C	5.188e^-5	0.975	INTERGENIC
2L	3083505	2L_3083505_INS [dm3] 2L_3083505_INS [dm6]	C	CGACATCC	5.237e^-5	0.975	INTRON toc	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_ftz BDTNP1_TFBS_Med BDTNP1_TFBS_prd BDTNP1_TFBS_sna BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_eve mE1_TFBS_HSA
3L	11189451	3L_11189451_SNP [dm3] 3L_11196351_SNP [dm6]	G	A	5.495e^-5	0.975	INTRON GlcAT-P	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi
2L	7844229	2L_7844229_SNP [dm3] 2L_7844229_SNP [dm6]	G	A	5.553e^-5	0.975	DOWNSTREAM CG14535 INTERGENIC
2L	7844242	2L_7844242_SNP [dm3] 2L_7844242_SNP [dm6]	A	C	5.553e^-5	0.975	DOWNSTREAM CG14535 INTERGENIC
3L	12406416	3L_12406416_SNP [dm3] 3L_12413316_SNP [dm6]	T	G	5.674e^-5	0.975	INTRON CG32103
2R	6784933	2R_6784933_INS [dm3] 2R_10897428_INS [dm6]	T	TT	5.722e^-5	0.975	DOWNSTREAM Rpb5 & 1 other INTRON CG7712	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad mE1_TFBS_sens mE1_TFBS_ttk
2L	11578470	2L_11578470_SNP [dm3] 2L_11578470_SNP [dm6]	A	G	5.732e^-5	0.975	INTERGENIC
2R	13040486	2R_13040486_SNP [dm3] 2R_17152981_SNP [dm6]	A	C	5.824e^-5	0.975	INTERGENIC
X	14787705	X_14787705_SNP [dm3] X_14893672_SNP [dm6]	A	C	5.890e^-5	0.975	INTRON Flo2 & 1 other
X	11315438	X_11315438_SNP [dm3] X_11421405_SNP [dm6]	G	T	6.088e^-5	0.975	INTERGENIC
X	11315455	X_11315455_SNP [dm3] X_11421422_SNP [dm6]	C	G	6.088e^-5	0.975	INTERGENIC
3L	4759671	3L_4759671_SNP [dm3] 3L_4759671_SNP [dm6]	C	A	6.175e^-5	0.975	DOWNSTREAM CG13711 INTRON RhoGEF64C	TF binding site BDTNP1_TFBS_twi mE1_TFBS_HSA
3L	4759708	3L_4759708_SNP [dm3] 3L_4759708_SNP [dm6]	G	A	6.175e^-5	0.975	DOWNSTREAM CG13711 INTRON RhoGEF64C	TF binding site BDTNP1_TFBS_twi mE1_TFBS_HSA
3L	4759743	3L_4759743_SNP [dm3] 3L_4759743_SNP [dm6]	C	T	6.175e^-5	0.975	INTRON RhoGEF64C	TF binding site BDTNP1_TFBS_twi mE1_TFBS_HSA
2L	5743055	2L_5743055_SNP [dm3] 2L_5743055_SNP [dm6]	T	C	6.325e^-5	0.975	INTRON CG11030
2L	5743070	2L_5743070_SNP [dm3] 2L_5743070_SNP [dm6]	T	A	6.325e^-5	0.975	INTRON CG11030
2L	5743076	2L_5743076_SNP [dm3] 2L_5743076_SNP [dm6]	A	C	6.325e^-5	0.975	INTRON CG11030
2L	5743099	2L_5743099_INS [dm3] 2L_5743099_INS [dm6]	A	ATCACTTGCAAGAAAGA...	6.325e^-5	0.975	INTRON CG11030
2L	5743107	2L_5743107_SNP [dm3] 2L_5743107_SNP [dm6]	T	A	6.325e^-5	0.975	INTRON CG11030
2L	5743139	2L_5743139_SNP [dm3] 2L_5743139_SNP [dm6]	A	T	6.325e^-5	0.975	INTRON CG11030
2L	5743142	2L_5743142_SNP [dm3] 2L_5743142_SNP [dm6]	T	A	6.325e^-5	0.975	INTRON CG11030
2L	5743146	2L_5743146_INS [dm3] 2L_5743146_INS [dm6]	T	TATGTATA	6.325e^-5	0.975	INTRON CG11030
2L	5743172	2L_5743172_SNP [dm3] 2L_5743172_SNP [dm6]	T	C	6.325e^-5	0.975	INTRON CG11030
2L	5743175	2L_5743175_SNP [dm3] 2L_5743175_SNP [dm6]	A	C	6.325e^-5	0.975	INTRON CG11030
2L	5743200	2L_5743200_SNP [dm3] 2L_5743200_SNP [dm6]	G	A	6.325e^-5	0.975	INTRON CG11030
2L	5743204	2L_5743204_MNP [dm3] 2L_5743204_MNP [dm6]	CAGTT	TGAAA	6.325e^-5	0.975	INTRON CG11030
2L	5743213	2L_5743213_DEL [dm3] 2L_5743213_DEL [dm6]	TCT	AA	6.325e^-5	0.975	INTRON CG11030
2L	5743284	2L_5743284_SNP [dm3] 2L_5743284_SNP [dm6]	A	G	6.325e^-5	0.975	INTRON CG11030
2L	5743286	2L_5743286_SNP [dm3] 2L_5743286_SNP [dm6]	T	G	6.325e^-5	0.975	INTRON CG11030
2L	5743532	2L_5743532_DEL [dm3] 2L_5743532_DEL [dm6]	TGAGTTTTAGAGCA...	T	6.325e^-5	0.975	INTRON CG11030
3L	11192362	3L_11192362_SNP [dm3] 3L_11199262_SNP [dm6]	T	C	6.372e^-5	0.975	SPLICE_SITE_REGION Plod UPSTREAM CG7607 INTRON Plod	TF binding site mE1_TFBS_sens

Showing 1 to 100 of 1,000 entries

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GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=5.472e^-1)
Null hypothesis is not rejected (p>0.05).
Interpretation: NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test

Covariate	p-value	Significance
In_3R_K	0.01289

Kruskal-Wallis test

Covariate	χ²	p-value	Significance
In_3R_K	4.1938	0.0406

PNG PDF

QQplot

PNG PDF

Manhattan plot

GWAS results

1357 significant hits at p-value < 0.001. The 1000 top results are displayed in the table below.

Variant impact HIGH MODERATE LOW MODIFIER

Show entries

Search:

Chromosome	Position	ID	Reference	Variant	p-value	FDR_BH	Transcript annotation	Binding site annotation
2L	11485934	2L_11485934_SNP [dm3] 2L_11485934_SNP [dm6]	C	T	1.262e^-7	0.111	UPSTREAM sala DOWNSTREAM CG43355 INTRON CG43355 & 1 other	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
2L	11485937	2L_11485937_SNP [dm3] 2L_11485937_SNP [dm6]	T	C	1.262e^-7	0.111	UPSTREAM sala DOWNSTREAM CG43355 INTRON CG43355 & 1 other	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
2L	11486035	2L_11486035_SNP [dm3] 2L_11486035_SNP [dm6]	G	C	3.853e^-7	0.227	UPSTREAM sala DOWNSTREAM CG43355 INTRON CG43355 & 1 other	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
2R	4727026	2R_4727026_SNP [dm3] 2R_8839521_SNP [dm6]	A	G	2.204e^-6	0.726	INTRON sns
2L	11486010	2L_11486010_SNP [dm3] 2L_11486010_SNP [dm6]	A	G	2.942e^-6	0.726	UPSTREAM sala DOWNSTREAM CG43355 INTRON CG43355 & 1 other	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
2L	11486093	2L_11486093_SNP [dm3] 2L_11486093_SNP [dm6]	A	C	3.916e^-6	0.726	UTR_5_PRIME sala UTR_3_PRIME CG43355 UPSTREAM sala DOWNSTREAM CG43355	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
3L	8413602	3L_8413602_DEL [dm3] 3L_8420502_DEL [dm6]	ATGT	A	3.940e^-6	0.726	INTRON CG32354
3L	13836110	3L_13836110_SNP [dm3] 3L_13843010_SNP [dm6]	G	T	4.461e^-6	0.726	UTR_5_PRIME CG8750 UPSTREAM CG8757 & 1 other
2L	15248135	2L_15248135_SNP [dm3] 2L_15248135_SNP [dm6]	A	T	5.517e^-6	0.726	UPSTREAM ZnT35C & 1 other INTERGENIC
2R	1756555	2R_1756555_SNP [dm3] 2R_5869050_SNP [dm6]	A	T	6.212e^-6	0.726	INTERGENIC
2L	15248161	2L_15248161_SNP [dm3] 2L_15248161_SNP [dm6]	T	A	6.741e^-6	0.726	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	15248164	2L_15248164_SNP [dm3] 2L_15248164_SNP [dm6]	G	C	6.741e^-6	0.726	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	15248172	2L_15248172_SNP [dm3] 2L_15248172_SNP [dm6]	T	A	6.741e^-6	0.726	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	15248180	2L_15248180_INS [dm3] 2L_15248180_INS [dm6]	G	GT	6.741e^-6	0.726	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	15248273	2L_15248273_DEL [dm3] 2L_15248273_DEL [dm6]	GCAG	G	6.992e^-6	0.726	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	15248188	2L_15248188_SNP [dm3] 2L_15248188_SNP [dm6]	A	T	7.007e^-6	0.726	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	11485417	2L_11485417_SNP [dm3] 2L_11485417_SNP [dm6]	C	T	7.442e^-6	0.726	NON_SYNONYMOUS_CODING CG43355 UTR_5_PRIME sala UPSTREAM sala	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad
2L	15248211	2L_15248211_SNP [dm3] 2L_15248211_SNP [dm6]	C	T	8.039e^-6	0.726	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	15248233	2L_15248233_SNP [dm3] 2L_15248233_SNP [dm6]	G	C	8.039e^-6	0.726	UPSTREAM ZnT35C & 1 other INTERGENIC
3R	2434700	3R_2434700_SNP [dm3] 3R_6608978_SNP [dm6]	G	A	8.220e^-6	0.726	UPSTREAM glob2 INTERGENIC
3L	13853242	3L_13853242_SNP [dm3] 3L_13860142_SNP [dm6]	A	C	1.031e^-5	0.867	UTR_3_PRIME CG8745 DOWNSTREAM Hml	TF binding site mE1_TFBS_bab1
2L	973537	2L_973537_SNP [dm3] 2L_973537_SNP [dm6]	C	T	1.204e^-5	0.946	INTERGENIC
3L	10674618	3L_10674618_SNP [dm3] 3L_10681518_SNP [dm6]	T	C	1.232e^-5	0.946	INTRON simj	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_GATAe mE1_TFBS_HSA mE1_TFBS_Trl
2R	1756660	2R_1756660_SNP [dm3] 2R_5869155_SNP [dm6]	C	T	1.614e^-5	0.979	INTERGENIC
3L	13853140	3L_13853140_SNP [dm3] 3L_13860040_SNP [dm6]	A	T	1.774e^-5	0.979	UTR_3_PRIME CG8745 DOWNSTREAM Hml	TF binding site mE1_TFBS_bab1 mE1_TFBS_cad
3L	13854094	3L_13854094_SNP [dm3] 3L_13860994_SNP [dm6]	G	A	1.774e^-5	0.979	SYNONYMOUS_CODING CG8745 DOWNSTREAM Hml	TF binding site mE1_TFBS_cad mE1_TFBS_chinmo mE1_TFBS_HSA mE1_TFBS_sens
2L	15248202	2L_15248202_SNP [dm3] 2L_15248202_SNP [dm6]	A	T	1.835e^-5	0.979	UPSTREAM ZnT35C & 1 other INTERGENIC
3L	11957569	3L_11957569_SNP [dm3] 3L_11964469_SNP [dm6]	A	T	2.039e^-5	0.979	SYNONYMOUS_CODING prc	TF binding site mE1_TFBS_chinmo
3L	13829341	3L_13829341_SNP [dm3] 3L_13836241_SNP [dm6]	T	G	2.089e^-5	0.979	INTERGENIC
2L	11578470	2L_11578470_SNP [dm3] 2L_11578470_SNP [dm6]	A	G	2.136e^-5	0.979	INTERGENIC
3L	11187892	3L_11187892_SNP [dm3] 3L_11194792_SNP [dm6]	T	C	2.165e^-5	0.979	INTRON GlcAT-P	TF binding site BDTNP1_TFBS_twi
3L	11188004	3L_11188004_SNP [dm3] 3L_11194904_SNP [dm6]	T	C	2.165e^-5	0.979	INTRON GlcAT-P	TF binding site BDTNP1_TFBS_twi
3L	12406416	3L_12406416_SNP [dm3] 3L_12413316_SNP [dm6]	T	G	2.181e^-5	0.979	INTRON CG32103
3L	13829293	3L_13829293_SNP [dm3] 3L_13836193_SNP [dm6]	G	A	2.329e^-5	0.979	INTERGENIC
3L	13836141	3L_13836141_SNP [dm3] 3L_13843041_SNP [dm6]	G	A	2.329e^-5	0.979	UPSTREAM CG8757 & 2 others INTERGENIC
2L	3102052	2L_3102052_SNP [dm3] 2L_3102052_SNP [dm6]	T	C	2.700e^-5	0.979	INTRON toc
2L	11485450	2L_11485450_SNP [dm3] 2L_11485450_SNP [dm6]	T	C	2.713e^-5	0.979	NON_SYNONYMOUS_CODING CG43355 UTR_5_PRIME sala UPSTREAM sala	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad
2R	1756321	2R_1756321_DEL [dm3] 2R_5868816_DEL [dm6]	TAGAATATTTATTCTTGATC...	T	2.830e^-5	0.979	INTERGENIC
2R	6740549	2R_6740549_SNP [dm3] 2R_10853044_SNP [dm6]	A	G	2.855e^-5	0.979	UPSTREAM CR45136 INTRON CG30015	TF binding site BDTNP1_TFBS_twi
2L	15248160	2L_15248160_SNP [dm3] 2L_15248160_SNP [dm6]	T	C	2.897e^-5	0.979	UPSTREAM ZnT35C & 1 other INTERGENIC
3R	4135967	3R_4135967_SNP [dm3] 3R_8310245_SNP [dm6]	A	T	2.972e^-5	0.979	UTR_5_PRIME CG11693 DOWNSTREAM CG11694 INTRON CG11693	TF binding site mE1_TFBS_chinmo mE1_TFBS_inv
2R	13045522	2R_13045522_SNP [dm3] 2R_17158017_SNP [dm6]	A	G	2.992e^-5	0.979	SYNONYMOUS_CODING CG17287 DOWNSTREAM CG17290 & 1 other
3L	11586119	3L_11586119_SNP [dm3] 3L_11593019_SNP [dm6]	A	G	3.011e^-5	0.979	UPSTREAM CR45442 & 1 other DOWNSTREAM CR45443 & 1 other INTERGENIC
2L	6752117	2L_6752117_SNP [dm3] 2L_6752117_SNP [dm6]	T	C	3.209e^-5	0.979	INTRON CG11221
2L	15248234	2L_15248234_SNP [dm3] 2L_15248234_SNP [dm6]	T	C	3.282e^-5	0.979	UPSTREAM ZnT35C & 1 other INTERGENIC
3L	12406434	3L_12406434_SNP [dm3] 3L_12413334_SNP [dm6]	T	C	3.510e^-5	0.979	INTRON CG32103
3L	11187715	3L_11187715_SNP [dm3] 3L_11194615_SNP [dm6]	G	A	3.524e^-5	0.979	INTRON GlcAT-P
2L	3083578	2L_3083578_SNP [dm3] 2L_3083578_SNP [dm6]	C	T	3.641e^-5	0.979	INTRON toc	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_prd BDTNP1_TFBS_sna BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_eve mE1_TFBS_HSA
3L	5985151	3L_5985151_SNP [dm3] 3L_5992051_SNP [dm6]	G	C	3.892e^-5	0.979	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi
X	4068127	X_4068127_SNP [dm3] X_4174094_SNP [dm6]	T	C	3.915e^-5	0.979	INTRON Fas2
X	4068131	X_4068131_SNP [dm3] X_4174098_SNP [dm6]	G	C	3.915e^-5	0.979	INTRON Fas2
2L	16043751	2L_16043751_SNP [dm3] 2L_16043751_SNP [dm6]	A	T	3.938e^-5	0.979	UPSTREAM BicC INTRON BicC & 1 other
3R	25999651	3R_25999651_SNP [dm3] 3R_30173929_SNP [dm6]	G	A	4.212e^-5	0.979	INTRON Mlc2
3L	12406414	3L_12406414_SNP [dm3] 3L_12413314_SNP [dm6]	G	T	4.275e^-5	0.979	INTRON CG32103
2R	19704491	2R_19704491_SNP [dm3] 2R_23816968_SNP [dm6]	C	T	4.316e^-5	0.979	INTRON CG4797
3R	2435982	3R_2435982_SNP [dm3] 3R_6610260_SNP [dm6]	T	C	4.482e^-5	0.979	INTERGENIC
2R	13044615	2R_13044615_SNP [dm3] 2R_17157110_SNP [dm6]	C	T	4.556e^-5	0.979	UTR_3_PRIME CG17290 & 1 other
2L	7844229	2L_7844229_SNP [dm3] 2L_7844229_SNP [dm6]	G	A	4.618e^-5	0.979	DOWNSTREAM CG14535 INTERGENIC
2L	7844242	2L_7844242_SNP [dm3] 2L_7844242_SNP [dm6]	A	C	4.618e^-5	0.979	DOWNSTREAM CG14535 INTERGENIC
3L	4099915	3L_4099915_SNP [dm3] 3L_4099915_SNP [dm6]	T	C	4.698e^-5	0.979	INTRON CG14995	TF binding site mE1_TFBS_inv
3L	2554573	3L_2554573_SNP [dm3] 3L_2554573_SNP [dm6]	A	T	4.995e^-5	0.979	UPSTREAM Spn DOWNSTREAM msn INTERGENIC	TF binding site BDTNP1_TFBS_dl mE1_TFBS_bab1 mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_kn mE1_TFBS_sbb mE1_TFBS_Ubx
3L	11189451	3L_11189451_SNP [dm3] 3L_11196351_SNP [dm6]	G	A	5.159e^-5	0.979	INTRON GlcAT-P	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi
2L	3083505	2L_3083505_INS [dm3] 2L_3083505_INS [dm6]	C	CGACATCC	5.295e^-5	0.979	INTRON toc	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_ftz BDTNP1_TFBS_Med BDTNP1_TFBS_prd BDTNP1_TFBS_sna BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_eve mE1_TFBS_HSA
2L	11486051	2L_11486051_SNP [dm3] 2L_11486051_SNP [dm6]	G	T	5.391e^-5	0.979	UPSTREAM sala DOWNSTREAM CG43355 INTRON CG43355 & 1 other	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
3L	14310944	3L_14310944_SNP [dm3] 3L_14317844_SNP [dm6]	T	A	5.421e^-5	0.979	INTRON fz
X	2475865	X_2475865_SNP [dm3] X_2581832_SNP [dm6]	T	C	5.486e^-5	0.979	UPSTREAM CG13759 INTRON CG13759
3L	13837633	3L_13837633_SNP [dm3] 3L_13844533_SNP [dm6]	T	G	5.524e^-5	0.979	SYNONYMOUS_CODING Tsp68C	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
3R	2434943	3R_2434943_SNP [dm3] 3R_6609221_SNP [dm6]	G	A	5.584e^-5	0.979	UPSTREAM glob2 INTERGENIC
2L	15248088	2L_15248088_SNP [dm3] 2L_15248088_SNP [dm6]	T	A	5.676e^-5	0.979	UPSTREAM ZnT35C & 1 other INTERGENIC
2L	13632552	2L_13632552_SNP [dm3] 2L_13632552_SNP [dm6]	C	A	5.769e^-5	0.979	DOWNSTREAM CR43410 INTRON kuz
2L	13632565	2L_13632565_SNP [dm3] 2L_13632565_SNP [dm6]	T	C	5.769e^-5	0.979	DOWNSTREAM CR43410 INTRON kuz
2L	13632570	2L_13632570_SNP [dm3] 2L_13632570_SNP [dm6]	C	G	5.769e^-5	0.979	DOWNSTREAM CR43410 INTRON kuz
2R	18755771	2R_18755771_SNP [dm3] 2R_22868248_SNP [dm6]	T	C	6.076e^-5	0.979	UTR_5_PRIME fd59A	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA mE1_TFBS_Trl
3R	22747303	3R_22747303_INS [dm3] 3R_26921581_INS [dm6]	A	AG	6.125e^-5	0.979	INTRON sda
3L	13853232	3L_13853232_SNP [dm3] 3L_13860132_SNP [dm6]	C	A	6.212e^-5	0.979	UTR_3_PRIME CG8745 DOWNSTREAM Hml	TF binding site mE1_TFBS_bab1
2L	7844231	2L_7844231_SNP [dm3] 2L_7844231_SNP [dm6]	T	A	6.238e^-5	0.979	DOWNSTREAM CG14535 INTERGENIC
3L	13856161	3L_13856161_SNP [dm3] 3L_13863061_SNP [dm6]	C	A	6.297e^-5	0.979	INTRON CG8745	enhancer mE1_CBP_Enhancers TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi BDTNP1_TFBS_z mE1_TFBS_HSA
3L	5985152	3L_5985152_SNP [dm3] 3L_5992052_SNP [dm6]	A	G	6.886e^-5	0.979	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi
2R	6784933	2R_6784933_INS [dm3] 2R_10897428_INS [dm6]	T	TT	7.184e^-5	0.979	DOWNSTREAM Rpb5 & 1 other INTRON CG7712	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad mE1_TFBS_sens mE1_TFBS_ttk
3L	22885109	3L_22885109_SNP [dm3] 3L_22892009_SNP [dm6]	A	G	7.252e^-5	0.979	NON_SYNONYMOUS_CODING slif	TF binding site mE1_TFBS_cad mE1_TFBS_chinmo
3L	13844706	3L_13844706_SNP [dm3] 3L_13851606_SNP [dm6]	A	G	7.346e^-5	0.979	SYNONYMOUS_CODING Hml	TF binding site mE1_TFBS_cad
3L	13844823	3L_13844823_SNP [dm3] 3L_13851723_SNP [dm6]	C	A	7.346e^-5	0.979	NON_SYNONYMOUS_CODING Hml	TF binding site mE1_TFBS_cad
X	8633311	X_8633311_SNP [dm3] X_8739278_SNP [dm6]	A	G	7.555e^-5	0.979	INTERGENIC
3L	9313008	3L_9313008_SNP [dm3] 3L_9319908_SNP [dm6]	G	A	7.666e^-5	0.979	INTERGENIC
3L	18142950	3L_18142950_SNP [dm3] 3L_18149850_SNP [dm6]	T	C	7.670e^-5	0.979	INTRON CG7330
X	4068190	X_4068190_SNP [dm3] X_4174157_SNP [dm6]	A	C	7.716e^-5	0.979	INTRON Fas2
3L	13835565	3L_13835565_SNP [dm3] 3L_13842465_SNP [dm6]	G	C	7.787e^-5	0.979	UTR_3_PRIME CG8750 UPSTREAM CG8757 DOWNSTREAM CG8750
3L	13853228	3L_13853228_SNP [dm3] 3L_13860128_SNP [dm6]	C	T	7.787e^-5	0.979	UTR_3_PRIME CG8745 DOWNSTREAM Hml	TF binding site mE1_TFBS_bab1
3L	11187945	3L_11187945_SNP [dm3] 3L_11194845_SNP [dm6]	C	A	8.100e^-5	0.979	INTRON GlcAT-P	TF binding site BDTNP1_TFBS_twi
2L	16043771	2L_16043771_SNP [dm3] 2L_16043771_SNP [dm6]	G	C	8.235e^-5	0.979	UPSTREAM BicC INTRON BicC & 1 other
3L	12591599	3L_12591599_SNP [dm3] 3L_12598499_SNP [dm6]	A	G	8.381e^-5	0.979	INTERGENIC
X	3765012	X_3765012_SNP [dm3] X_3870979_SNP [dm6]	T	G	8.615e^-5	0.979	INTRON yin & 1 other	TF binding site mE1_TFBS_inv
3L	10734120	3L_10734120_SNP [dm3] 3L_10741020_SNP [dm6]	T	A	8.652e^-5	0.979	INTERGENIC	TF binding site BDTNP1_TFBS_dl
3L	13829043	3L_13829043_SNP [dm3] 3L_13835943_SNP [dm6]	C	T	8.714e^-5	0.979	INTERGENIC
2L	12953184	2L_12953184_SNP [dm3] 2L_12953184_SNP [dm6]	T	C	9.056e^-5	0.979	INTERGENIC
2L	7844264	2L_7844264_SNP [dm3] 2L_7844264_SNP [dm6]	T	A	9.186e^-5	0.979	DOWNSTREAM CG14535 INTERGENIC
2L	7844269	2L_7844269_INS [dm3] 2L_7844269_INS [dm6]	T	TT	9.186e^-5	0.979	DOWNSTREAM CG14535 INTERGENIC
3L	4637228	3L_4637228_INS [dm3] 3L_4637228_INS [dm6]	C	CGC	9.298e^-5	0.979	UTR_3_PRIME axo INTRON axo
2R	4631641	2R_4631641_SNP [dm3] 2R_8744136_SNP [dm6]	C	T	9.430e^-5	0.979	INTRON CG8740 EXON CR44277
3L	2210668	3L_2210668_SNP [dm3] 3L_2210668_SNP [dm6]	G	A	9.471e^-5	0.979	DOWNSTREAM CG15878 INTERGENIC

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alive phenotype

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Phenotype distribution and association to known covariates

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GWAS results