DGRPool

GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=6.408e^-1)
Null hypothesis is not rejected (p>0.05).
Interpretation: NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test
No significant result.

Kruskal-Wallis test
No significant result.

PNG PDF

QQplot

PNG PDF

Manhattan plot

GWAS results

2134 significant hits at p-value < 0.001. The 1000 top results are displayed in the table below.

We performed a gene enrichment calculation (Fisher's exact test) of all GWAS-associated genes at p < 0.001. Genesets were taken from two database: the Gene Ontology (GO) and the FlyBase phenotypes. GO enrichment FlyBase phenotype enrichment

Variant impact HIGH MODERATE LOW MODIFIER

Show entries

Search:

Chromosome	Position	ID	Reference	Variant	p-value	FDR_BH	Transcript annotation	Binding site annotation
2R	20216108	2R_20216108_SNP [dm3] 2R_24328585_SNP [dm6]	G	T	1.311e^-7	0.246	UPSTREAM CR44810 INTRON CR44810
2R	20215213	2R_20215213_SNP [dm3] 2R_24327690_SNP [dm6]	A	G	3.459e^-7	0.324	INTRON CR44810
2L	13930052	2L_13930052_SNP [dm3] 2L_13930052_SNP [dm6]	T	C	9.226e^-7	0.577	DOWNSTREAM CG42711 INTRON Ance-3
X	3430515	X_3430515_SNP [dm3] X_3536482_SNP [dm6]	C	A	2.006e^-6	0.647	INTRON CG32791
3L	2488424	3L_2488424_SNP [dm3] 3L_2488424_SNP [dm6]	A	T	2.896e^-6	0.647	UPSTREAM CG1146 INTRON CG45186	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
3L	2488440	3L_2488440_SNP [dm3] 3L_2488440_SNP [dm6]	G	T	2.916e^-6	0.647	UPSTREAM CG1146 INTRON CG45186	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
3R	7871189	3R_7871189_SNP [dm3] 3R_12045467_SNP [dm6]	G	A	2.942e^-6	0.647	INTERGENIC
2R	20215851	2R_20215851_SNP [dm3] 2R_24328328_SNP [dm6]	G	T	3.407e^-6	0.647	UPSTREAM CR44810 INTRON CR44810
2R	20217082	2R_20217082_SNP [dm3] 2R_24329559_SNP [dm6]	T	A	3.927e^-6	0.647	UPSTREAM CR44810 INTRON CR44810 EXON CR44810	TF binding site mE1_TFBS_Trl
3L	2488423	3L_2488423_SNP [dm3] 3L_2488423_SNP [dm6]	A	C	3.983e^-6	0.647	UPSTREAM CG1146 INTRON CG45186	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
2L	13427920	2L_13427920_SNP [dm3] 2L_13427920_SNP [dm6]	A	G	4.695e^-6	0.647	INTRON CG42784
2R	20217991	2R_20217991_SNP [dm3] 2R_24330468_SNP [dm6]	C	T	5.865e^-6	0.647	DOWNSTREAM CR44810 INTERGENIC	TF binding site mE1_TFBS_cad mE1_TFBS_Trl
X	3156785	X_3156785_SNP [dm3] X_3262752_SNP [dm6]	G	T	5.928e^-6	0.647	INTRON dnc
X	3430518	X_3430518_SNP [dm3] X_3536485_SNP [dm6]	G	C	6.994e^-6	0.647	INTRON CG32791
3L	14181404	3L_14181404_SNP [dm3] 3L_14188304_SNP [dm6]	G	C	7.181e^-6	0.647	INTRON nan
2L	11644034	2L_11644034_SNP [dm3] 2L_11644034_SNP [dm6]	T	A	7.905e^-6	0.647	DOWNSTREAM CG6614 INTERGENIC
2R	20216744	2R_20216744_SNP [dm3] 2R_24329221_SNP [dm6]	C	T	8.617e^-6	0.647	UPSTREAM CR44810 INTRON CR44810 EXON CR44810	TF binding site mE1_TFBS_Trl
3R	7879020	3R_7879020_SNP [dm3] 3R_12053298_SNP [dm6]	G	T	9.077e^-6	0.647	INTERGENIC
X	3430506	X_3430506_SNP [dm3] X_3536473_SNP [dm6]	C	T	9.355e^-6	0.647	INTRON CG32791
2R	11585565	2R_11585565_SNP [dm3] 2R_15698060_SNP [dm6]	A	T	9.438e^-6	0.647	DOWNSTREAM CG30080 & 2 others INTERGENIC	TF binding site mE1_TFBS_bab1
2L	4389085	2L_4389085_SNP [dm3] 2L_4389085_SNP [dm6]	G	A	1.022e^-5	0.647	INTRON Tps1
3L	6560042	3L_6560042_SNP [dm3] 3L_6566942_SNP [dm6]	G	A	1.043e^-5	0.647	SYNONYMOUS_CODING jv INTRON CG18769
3L	18006448	3L_18006448_SNP [dm3] 3L_18013348_SNP [dm6]	A	T	1.044e^-5	0.647	INTRON Eip75B	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
3L	2488448	3L_2488448_SNP [dm3] 3L_2488448_SNP [dm6]	G	A	1.079e^-5	0.647	UPSTREAM CG1146 INTRON CG45186	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
2R	11585720	2R_11585720_SNP [dm3] 2R_15698215_SNP [dm6]	T	G	1.134e^-5	0.647	DOWNSTREAM CG30080 & 2 others INTERGENIC	TF binding site mE1_TFBS_bab1 mE1_TFBS_HSA
2R	9737845	2R_9737845_SNP [dm3] 2R_13850340_SNP [dm6]	C	T	1.135e^-5	0.647	SYNONYMOUS_CODING CG30485 DOWNSTREAM CG30484
2R	11585560	2R_11585560_SNP [dm3] 2R_15698055_SNP [dm6]	C	G	1.157e^-5	0.647	DOWNSTREAM CG30080 & 2 others INTERGENIC	TF binding site mE1_TFBS_bab1
2L	10313303	2L_10313303_SNP [dm3] 2L_10313303_SNP [dm6]	T	C	1.160e^-5	0.647	SPLICE_SITE_REGION CG5384 INTRON CG5384	TF binding site BDTNP1_TFBS_dl
2R	18381794	2R_18381794_SNP [dm3] 2R_22494289_SNP [dm6]	G	T	1.185e^-5	0.647	UTR_3_PRIME CG4610 DOWNSTREAM px
2R	20214627	2R_20214627_SNP [dm3] 2R_24327104_SNP [dm6]	G	A	1.186e^-5	0.647	INTRON CR44810
3R	4371893	3R_4371893_SNP [dm3] 3R_8546171_SNP [dm6]	T	C	1.216e^-5	0.647	UPSTREAM CR45574 DOWNSTREAM CR45575 INTERGENIC
X	20401923	X_20401923_SNP [dm3] X_20530896_SNP [dm6]	C	A	1.265e^-5	0.647	INTERGENIC
2R	20213504	2R_20213504_SNP [dm3] 2R_24325981_SNP [dm6]	T	C	1.267e^-5	0.647	INTRON CR44810
X	16290951	X_16290951_SNP [dm3] X_16396918_SNP [dm6]	T	C	1.306e^-5	0.647	SYNONYMOUS_CODING mei-41	TF binding site mE1_TFBS_chinmo
X	13411607	X_13411607_SNP [dm3] X_13517574_SNP [dm6]	T	C	1.321e^-5	0.647	INTRON Neto	TF binding site BDTNP1_TFBS_dl
2L	3880016	2L_3880016_SNP [dm3] 2L_3880016_SNP [dm6]	T	C	1.343e^-5	0.647	UTR_5_PRIME capu INTRON capu
2L	2633977	2L_2633977_DEL [dm3] 2L_2633977_DEL [dm6]	TG	T	1.362e^-5	0.647	INTERGENIC	TF binding site mE1_TFBS_HSA mE1_TFBS_sbb
X	13411608	X_13411608_SNP [dm3] X_13517575_SNP [dm6]	T	A	1.401e^-5	0.647	INTRON Neto	TF binding site BDTNP1_TFBS_dl
2R	20207935	2R_20207935_SNP [dm3] 2R_24320412_SNP [dm6]	C	T	1.420e^-5	0.647	INTERGENIC
3L	22556737	3L_22556737_DEL [dm3] 3L_22563637_DEL [dm6]	CG	C	1.431e^-5	0.647	INTERGENIC	TF binding site BDTNP1_TFBS_twi mE1_TFBS_HSA
X	8177550	X_8177550_SNP [dm3] X_8283517_SNP [dm6]	T	C	1.431e^-5	0.647	INTRON nAChRalpha3
2L	11640516	2L_11640516_SNP [dm3] 2L_11640516_SNP [dm6]	A	G	1.450e^-5	0.647	INTERGENIC
2L	3376806	2L_3376806_SNP [dm3] 2L_3376806_SNP [dm6]	T	G	1.483e^-5	0.647	UPSTREAM Ptpa & 1 other INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA mE1_TFBS_Ubx
2R	20239564	2R_20239564_SNP [dm3] 2R_24352041_SNP [dm6]	G	A	1.630e^-5	0.669	UPSTREAM CG44812 INTRON bs EXON CR44811	TF binding site mE1_TFBS_chinmo
2L	2633914	2L_2633914_SNP [dm3] 2L_2633914_SNP [dm6]	G	C	1.636e^-5	0.669	INTERGENIC	TF binding site mE1_TFBS_HSA mE1_TFBS_sbb
2R	19917242	2R_19917242_SNP [dm3] 2R_24029719_SNP [dm6]	G	A	1.642e^-5	0.669	SYNONYMOUS_CODING CG3163 UPSTREAM HSPC300 DOWNSTREAM CG30172	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_sens
2R	20217670	2R_20217670_DEL [dm3] 2R_24330147_DEL [dm6]	GCTGAAG	G	1.761e^-5	0.703	EXON CR44810	TF binding site mE1_TFBS_Trl
2L	12444730	2L_12444730_SNP [dm3] 2L_12444730_SNP [dm6]	T	A	1.877e^-5	0.713	INTRON Oatp33Ea	TF binding site BDTNP1_TFBS_da
3L	9654121	3L_9654121_SNP [dm3] 3L_9661021_SNP [dm6]	A	T	1.900e^-5	0.713	INTRON fry	TF binding site BDTNP1_TFBS_twi
2R	12858868	2R_12858868_SNP [dm3] 2R_16971363_SNP [dm6]	T	C	1.901e^-5	0.713	EXON CR44377
2L	2633969	2L_2633969_SNP [dm3] 2L_2633969_SNP [dm6]	T	G	1.991e^-5	0.724	INTERGENIC	TF binding site mE1_TFBS_HSA mE1_TFBS_sbb
3R	18119410	3R_18119410_SNP [dm3] 3R_22293688_SNP [dm6]	T	A	2.036e^-5	0.724	SYNONYMOUS_CODING SKIP DOWNSTREAM mir-1010	TF binding site mE1_TFBS_cad mE1_TFBS_chinmo mE1_TFBS_HSA
2R	8428066	2R_8428066_SNP [dm3] 2R_12540561_SNP [dm6]	G	A	2.080e^-5	0.724	INTRON fra	TF binding site mE1_TFBS_cad mE1_TFBS_HSA
3R	19573626	3R_19573626_SNP [dm3] 3R_23747904_SNP [dm6]	C	A	2.136e^-5	0.724	SYNONYMOUS_CODING Hmgcr	TF binding site mE1_TFBS_cad
2L	10314163	2L_10314163_SNP [dm3] 2L_10314163_SNP [dm6]	A	G	2.137e^-5	0.724	SYNONYMOUS_CODING CG5384 UPSTREAM CG4972	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_cad mE1_TFBS_cnc mE1_TFBS_HSA mE1_TFBS_Ubx
3L	15305510	3L_15305510_DEL [dm3] 3L_15312410_DEL [dm6]	TTT	AG	2.207e^-5	0.724	INTERGENIC	TF binding site mE1_TFBS_sens
3L	17756004	3L_17756004_SNP [dm3] 3L_17762904_SNP [dm6]	T	A	2.238e^-5	0.724	UTR_3_PRIME CG32181 INTRON Adgf-A & 1 other
3R	18476473	3R_18476473_SNP [dm3] 3R_22650751_SNP [dm6]	T	A	2.255e^-5	0.724	INTRON CG45058
X	8177250	X_8177250_SNP [dm3] X_8283217_SNP [dm6]	A	C	2.331e^-5	0.724	INTRON nAChRalpha3
2L	3319742	2L_3319742_SNP [dm3] 2L_3319742_SNP [dm6]	T	A	2.342e^-5	0.724	UPSTREAM CG8837 INTRON CG3326	TF binding site BDTNP1_TFBS_dl mE1_TFBS_h mE1_TFBS_HSA
2R	18489624	2R_18489624_SNP [dm3] 2R_22602119_SNP [dm6]	T	G	2.355e^-5	0.724	NON_SYNONYMOUS_CODING CG4294
3L	14580641	3L_14580641_SNP [dm3] 3L_14587541_SNP [dm6]	C	G	2.465e^-5	0.732	INTRON HGTX
X	21089702	X_21089702_SNP [dm3] X_21218675_SNP [dm6]	T	C	2.475e^-5	0.732	SYNONYMOUS_CODING CG32523 INTRON CG32521	TF binding site mE1_TFBS_chinmo mE1_TFBS_HSA
X	20401936	X_20401936_SNP [dm3] X_20530909_SNP [dm6]	C	A	2.498e^-5	0.732	INTERGENIC
X	16403494	X_16403494_SNP [dm3] X_16509461_SNP [dm6]	C	T	2.586e^-5	0.733	INTRON para
2R	11080045	2R_11080045_SNP [dm3] 2R_15192540_SNP [dm6]	A	C	2.593e^-5	0.733	DOWNSTREAM Sfp51E INTERGENIC
3R	18118744	3R_18118744_SNP [dm3] 3R_22293022_SNP [dm6]	A	G	2.618e^-5	0.733	SYNONYMOUS_CODING SKIP DOWNSTREAM mir-1010
3L	6378337	3L_6378337_SNP [dm3] 3L_6385237_SNP [dm6]	G	A	2.749e^-5	0.757	INTERGENIC
3R	18119419	3R_18119419_SNP [dm3] 3R_22293697_SNP [dm6]	C	A	2.807e^-5	0.757	SYNONYMOUS_CODING SKIP DOWNSTREAM mir-1010	TF binding site mE1_TFBS_cad mE1_TFBS_chinmo mE1_TFBS_HSA
2L	3376818	2L_3376818_SNP [dm3] 2L_3376818_SNP [dm6]	C	T	2.826e^-5	0.757	UPSTREAM Ptpa & 1 other INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA mE1_TFBS_Ubx
X	13411553	X_13411553_SNP [dm3] X_13517520_SNP [dm6]	G	T	2.894e^-5	0.763	INTRON Neto	TF binding site BDTNP1_TFBS_dl
X	3522579	X_3522579_DEL [dm3] X_3628546_DEL [dm6]	TT	T	3.017e^-5	0.763	INTRON AstA-R1
2L	13427908	2L_13427908_SNP [dm3] 2L_13427908_SNP [dm6]	A	G	3.029e^-5	0.763	INTRON CG42784
2R	13504293	2R_13504293_SNP [dm3] 2R_17616788_SNP [dm6]	G	A	3.158e^-5	0.763	UTR_3_PRIME CG44403 INTRON CG10936 EXON snoRNA:Or-aca4	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
3L	22540278	3L_22540278_SNP [dm3] 3L_22547178_SNP [dm6]	C	T	3.203e^-5	0.763	INTERGENIC
X	8177327	X_8177327_SNP [dm3] X_8283294_SNP [dm6]	G	T	3.207e^-5	0.763	INTRON nAChRalpha3
3R	5020544	3R_5020544_SNP [dm3] 3R_9194822_SNP [dm6]	C	A	3.297e^-5	0.763	INTRON pum
2R	13504286	2R_13504286_SNP [dm3] 2R_17616781_SNP [dm6]	A	G	3.374e^-5	0.763	UTR_3_PRIME CG44403 INTRON CG10936 EXON snoRNA:Or-aca4	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
2L	11031615	2L_11031615_SNP [dm3] 2L_11031615_SNP [dm6]	C	G	3.390e^-5	0.763	INTRON Samuel
3R	8488105	3R_8488105_SNP [dm3] 3R_12662383_SNP [dm6]	T	A	3.432e^-5	0.763	UPSTREAM CG14395 & 1 other INTERGENIC	TF binding site mE1_TFBS_chinmo
2L	11640890	2L_11640890_SNP [dm3] 2L_11640890_SNP [dm6]	C	T	3.461e^-5	0.763	INTERGENIC
2L	2633931	2L_2633931_SNP [dm3] 2L_2633931_SNP [dm6]	T	G	3.585e^-5	0.763	INTERGENIC	TF binding site mE1_TFBS_HSA mE1_TFBS_sbb
2L	12629801	2L_12629801_SNP [dm3] 2L_12629801_SNP [dm6]	A	C	3.598e^-5	0.763	INTRON Ref2
3L	1682162	3L_1682162_SNP [dm3] 3L_1682162_SNP [dm6]	T	A	3.626e^-5	0.763	INTRON CG7991
2L	20004908	2L_20004908_SNP [dm3] 2L_20004908_SNP [dm6]	G	A	3.642e^-5	0.763	INTRON CG43861
2L	16131898	2L_16131898_SNP [dm3] 2L_16131898_SNP [dm6]	A	G	3.659e^-5	0.763	INTERGENIC
2L	20029874	2L_20029874_SNP [dm3] 2L_20029874_SNP [dm6]	C	A	3.674e^-5	0.763	INTRON sNPF
3L	2254163	3L_2254163_SNP [dm3] 3L_2254163_SNP [dm6]	G	A	3.794e^-5	0.763	INTRON CG1275	TF binding site mE1_TFBS_cad
2R	13504252	2R_13504252_INS [dm3] 2R_17616747_INS [dm6]	T	TGAAATAATAT...	3.817e^-5	0.763	UTR_3_PRIME CG44403 UPSTREAM snoRNA:Or-aca4 INTRON CG10936	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
3L	21252333	3L_21252333_SNP [dm3] 3L_21259233_SNP [dm6]	A	G	3.837e^-5	0.763	DOWNSTREAM CG43218 INTRON Eip78C
X	20641415	X_20641415_SNP [dm3] X_20770388_SNP [dm6]	T	A	3.843e^-5	0.763	UTR_3_PRIME shakB DOWNSTREAM shakB
2L	583288	2L_583288_SNP [dm3] 2L_583288_SNP [dm6]	C	A	3.894e^-5	0.763	DOWNSTREAM Gsc INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_sens
3L	2759020	3L_2759020_SNP [dm3] 3L_2759020_SNP [dm6]	G	T	3.910e^-5	0.763	INTRON Mrtf	TF binding site mE1_TFBS_HSA
X	4487249	X_4487249_SNP [dm3] X_4593216_SNP [dm6]	T	A	3.925e^-5	0.763	INTRON CR32773	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl
3L	12853593	3L_12853593_SNP [dm3] 3L_12860493_SNP [dm6]	C	T	3.939e^-5	0.763	NON_SYNONYMOUS_CODING CG32107	TF binding site mE1_TFBS_sens
3R	18118802	3R_18118802_SNP [dm3] 3R_22293080_SNP [dm6]	A	T	4.005e^-5	0.763	DOWNSTREAM mir-1010 INTRON SKIP
2L	7753667	2L_7753667_SNP [dm3] 2L_7753667_SNP [dm6]	G	A	4.068e^-5	0.763	UPSTREAM CG7203 & 1 other DOWNSTREAM CR45718 INTERGENIC
3L	5206682	3L_5206682_SNP [dm3] 3L_5213582_SNP [dm6]	A	T	4.084e^-5	0.763	INTRON shep
3R	6267480	3R_6267480_SNP [dm3] 3R_10441758_SNP [dm6]	C	T	4.124e^-5	0.763	INTERGENIC
2R	20211274	2R_20211274_SNP [dm3] 2R_24323751_SNP [dm6]	T	A	4.171e^-5	0.763	INTERGENIC

Showing 1 to 100 of 1,000 entries

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GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=3.069e^-1)
Null hypothesis is not rejected (p>0.05).
Interpretation: NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test

Covariate	p-value	Significance
In_3R_K	0.007322
In_3R_Mo	0.070502

Kruskal-Wallis test

Covariate	χ²	p-value	Significance
In_3R_K	8.4901	0.0143
In_3R_Mo	4.8898	0.0867

PNG PDF

QQplot

PNG PDF

Manhattan plot

GWAS results

1905 significant hits at p-value < 0.001. The 1000 top results are displayed in the table below.

Variant impact HIGH MODERATE LOW MODIFIER

Show entries

Search:

Chromosome	Position	ID	Reference	Variant	p-value	FDR_BH	Transcript annotation	Binding site annotation
3R	8488105	3R_8488105_SNP [dm3] 3R_12662383_SNP [dm6]	T	A	7.174e^-7	0.879	UPSTREAM CG14395 & 1 other INTERGENIC	TF binding site mE1_TFBS_chinmo
3R	8527008	3R_8527008_SNP [dm3] 3R_12701286_SNP [dm6]	G	A	2.652e^-6	0.879	INTRON Past1
X	17256743	X_17256743_SNP [dm3] X_17362710_SNP [dm6]	G	A	3.176e^-6	0.879	INTERGENIC
X	7433303	X_7433303_SNP [dm3] X_7539270_SNP [dm6]	T	A	3.556e^-6	0.879	INTRON CG32719
2L	3376806	2L_3376806_SNP [dm3] 2L_3376806_SNP [dm6]	T	G	3.777e^-6	0.879	UPSTREAM Ptpa & 1 other INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA mE1_TFBS_Ubx
3R	20304772	3R_20304772_SNP [dm3] 3R_24479050_SNP [dm6]	C	A	4.181e^-6	0.879	INTERGENIC
2R	17864733	2R_17864733_SNP [dm3] 2R_21977228_SNP [dm6]	A	G	4.609e^-6	0.879	SYNONYMOUS_CODING Gr58c DOWNSTREAM CG9304 & 1 other	TF binding site mE1_TFBS_sens
X	5330003	X_5330003_SNP [dm3] X_5435970_SNP [dm6]	C	A	4.624e^-6	0.879	DOWNSTREAM CR44471 INTERGENIC	TF binding site mE1_TFBS_HSA mE1_TFBS_sbb
2L	3376818	2L_3376818_SNP [dm3] 2L_3376818_SNP [dm6]	C	T	4.734e^-6	0.879	UPSTREAM Ptpa & 1 other INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA mE1_TFBS_Ubx
X	7433384	X_7433384_SNP [dm3] X_7539351_SNP [dm6]	G	A	5.470e^-6	0.879	INTRON CG32719
X	7433376	X_7433376_INS [dm3] X_7539343_INS [dm6]	G	GG	5.550e^-6	0.879	INTRON CG32719
X	7433393	X_7433393_SNP [dm3] X_7539360_SNP [dm6]	C	A	6.653e^-6	0.879	INTRON CG32719
X	18418964	X_18418964_SNP [dm3] X_18524931_SNP [dm6]	T	G	6.989e^-6	0.879	INTRON Bx
3R	10511898	3R_10511898_SNP [dm3] 3R_14686176_SNP [dm6]	T	C	7.335e^-6	0.879	INTRON Meltrin	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
3R	20304801	3R_20304801_DEL [dm3] 3R_24479079_DEL [dm6]	AA	A	8.042e^-6	0.879	INTERGENIC
2L	1176081	2L_1176081_SNP [dm3] 2L_1176081_SNP [dm6]	T	G	8.285e^-6	0.879	INTRON CG4887	TF binding site BDTNP1_TFBS_sna
2L	15186791	2L_15186791_SNP [dm3] 2L_15186791_SNP [dm6]	G	A	9.084e^-6	0.879	INTRON CG4168
2R	14780012	2R_14780012_SNP [dm3] 2R_18892507_SNP [dm6]	A	G	1.341e^-5	0.879	INTRON sano
2L	9608922	2L_9608922_SNP [dm3] 2L_9608922_SNP [dm6]	A	T	1.398e^-5	0.879	INTRON gcm2	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_Trl
X	7433354	X_7433354_SNP [dm3] X_7539321_SNP [dm6]	T	A	1.428e^-5	0.879	INTRON CG32719
3R	8544945	3R_8544945_SNP [dm3] 3R_12719223_SNP [dm6]	C	A	1.439e^-5	0.879	INTRON Men	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA mE1_TFBS_Trl
2L	4300936	2L_4300936_SNP [dm3] 2L_4300936_SNP [dm6]	T	G	1.476e^-5	0.879	INTRON tutl
3L	8093515	3L_8093515_SNP [dm3] 3L_8100415_SNP [dm6]	G	C	1.518e^-5	0.879	UPSTREAM Ect4 INTRON Ect4
X	19342124	X_19342124_SNP [dm3] X_19448091_SNP [dm6]	G	A	1.582e^-5	0.879	INTRON kek5
2L	14616790	2L_14616790_SNP [dm3] 2L_14616790_SNP [dm6]	C	T	1.584e^-5	0.879	SYNONYMOUS_CODING Adh UTR_5_PRIME Adhr UPSTREAM Adhr INTRON osp	TF binding site mE1_TFBS_cad
X	14493018	X_14493018_SNP [dm3] X_14598985_SNP [dm6]	A	T	1.588e^-5	0.879	INTRON CG9413
2L	9614121	2L_9614121_SNP [dm3] 2L_9614121_SNP [dm6]	A	T	1.668e^-5	0.879	INTRON Trx-2	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_prd BDTNP1_TFBS_twi mE1_TFBS_cnc mE1_TFBS_Trl
2L	9608604	2L_9608604_SNP [dm3] 2L_9608604_SNP [dm6]	T	A	1.682e^-5	0.879	UTR_5_PRIME gcm2	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl
3R	22619080	3R_22619080_SNP [dm3] 3R_26793358_SNP [dm6]	G	A	1.692e^-5	0.879	INTERGENIC	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
3R	8476376	3R_8476376_SNP [dm3] 3R_12650654_SNP [dm6]	T	A	1.792e^-5	0.879	INTRON Dtg	TF binding site BDTNP1_TFBS_da mE1_TFBS_bab1
3L	665734	3L_665734_SNP [dm3] 3L_665734_SNP [dm6]	C	T	1.823e^-5	0.879	INTERGENIC
2R	19373269	2R_19373269_SNP [dm3] 2R_23485746_SNP [dm6]	T	C	1.965e^-5	0.879	INTRON CG43795
2R	14779850	2R_14779850_SNP [dm3] 2R_18892345_SNP [dm6]	A	C	2.019e^-5	0.879	INTRON sano
3L	2047432	3L_2047432_SNP [dm3] 3L_2047432_SNP [dm6]	C	T	2.026e^-5	0.879	SYNONYMOUS_CODING sls	TF binding site mE1_TFBS_sens
X	3430506	X_3430506_SNP [dm3] X_3536473_SNP [dm6]	C	T	2.035e^-5	0.879	INTRON CG32791
X	8160396	X_8160396_SNP [dm3] X_8266363_SNP [dm6]	C	T	2.076e^-5	0.879	SYNONYMOUS_CODING CG1632	TF binding site BDTNP1_TFBS_dl mE1_TFBS_chinmo mE1_TFBS_HSA
X	16935406	X_16935406_SNP [dm3] X_17041373_SNP [dm6]	A	G	2.144e^-5	0.879	INTRON CG45002
3R	10966322	3R_10966322_SNP [dm3] 3R_15140600_SNP [dm6]	G	A	2.216e^-5	0.879	SYNONYMOUS_CODING CG3987 UPSTREAM CR45600
3R	8398746	3R_8398746_INS [dm3] 3R_12573024_INS [dm6]	A	ATTGAG	2.270e^-5	0.879	INTRON Octbeta2R
3R	26026664	3R_26026664_SNP [dm3] 3R_30200942_SNP [dm6]	C	A	2.361e^-5	0.879	INTRON CG9743	TF binding site mE1_TFBS_chinmo mE1_TFBS_HSA
2L	3378359	2L_3378359_SNP [dm3] 2L_3378359_SNP [dm6]	T	C	2.365e^-5	0.879	SYNONYMOUS_CODING Ptpa
3L	6439795	3L_6439795_SNP [dm3] 3L_6446695_SNP [dm6]	A	G	2.399e^-5	0.879	INTRON CG42747
X	3430515	X_3430515_SNP [dm3] X_3536482_SNP [dm6]	C	A	2.413e^-5	0.879	INTRON CG32791
3L	9654121	3L_9654121_SNP [dm3] 3L_9661021_SNP [dm6]	A	T	2.564e^-5	0.879	INTRON fry	TF binding site BDTNP1_TFBS_twi
3R	3438089	3R_3438089_SNP [dm3] 3R_7612367_SNP [dm6]	T	C	2.585e^-5	0.879	INTRON CG34127
X	15422282	X_15422282_SNP [dm3] X_15528249_SNP [dm6]	T	C	2.672e^-5	0.879	INTRON Ac13E
2L	3376830	2L_3376830_SNP [dm3] 2L_3376830_SNP [dm6]	C	T	2.709e^-5	0.879	UPSTREAM Ptpa & 1 other INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA mE1_TFBS_Ubx
X	10482099	X_10482099_SNP [dm3] X_10588066_SNP [dm6]	C	G	2.908e^-5	0.879	INTERGENIC
X	3430518	X_3430518_SNP [dm3] X_3536485_SNP [dm6]	G	C	2.936e^-5	0.879	INTRON CG32791
3R	11211074	3R_11211074_SNP [dm3] 3R_15385352_SNP [dm6]	G	T	2.947e^-5	0.879	NON_SYNONYMOUS_CODING Rbp	TF binding site mE1_TFBS_chinmo mE1_TFBS_HSA
X	8160393	X_8160393_SNP [dm3] X_8266360_SNP [dm6]	T	C	2.947e^-5	0.879	SYNONYMOUS_CODING CG1632	TF binding site BDTNP1_TFBS_dl mE1_TFBS_chinmo mE1_TFBS_HSA
X	1838379	X_1838379_SNP [dm3] X_1944346_SNP [dm6]	A	C	2.964e^-5	0.879	INTRON Hr4	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl
X	1832293	X_1832293_SNP [dm3] X_1938260_SNP [dm6]	T	C	2.977e^-5	0.879	UTR_3_PRIME CG3857	TF binding site BDTNP1_TFBS_twi mE1_TFBS_cad
2L	15367244	2L_15367244_SNP [dm3] 2L_15367244_SNP [dm6]	T	C	2.990e^-5	0.879	INTERGENIC
X	7433355	X_7433355_SNP [dm3] X_7539322_SNP [dm6]	G	A	3.009e^-5	0.879	INTRON CG32719
3L	20537695	3L_20537695_SNP [dm3] 3L_20544595_SNP [dm6]	G	C	3.043e^-5	0.879	INTERGENIC
2R	19373277	2R_19373277_SNP [dm3] 2R_23485754_SNP [dm6]	A	C	3.107e^-5	0.879	INTRON CG43795
3R	22543937	3R_22543937_SNP [dm3] 3R_26718215_SNP [dm6]	G	C	3.172e^-5	0.879	UPSTREAM CG6425 INTRON CG5484	TF binding site mE1_TFBS_cad mE1_TFBS_chinmo
2R	12547479	2R_12547479_SNP [dm3] 2R_16659974_SNP [dm6]	T	G	3.284e^-5	0.879	UPSTREAM Picot INTRON Picot
2L	18039871	2L_18039871_SNP [dm3] 2L_18039871_SNP [dm6]	T	A	3.284e^-5	0.879	INTRON rdo
X	1822604	X_1822604_SNP [dm3] X_1928571_SNP [dm6]	C	T	3.290e^-5	0.879	SYNONYMOUS_CODING CG11596	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_HSA
2L	583001	2L_583001_SNP [dm3] 2L_583001_SNP [dm6]	A	T	3.322e^-5	0.879	DOWNSTREAM Gsc INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_twi mE1_TFBS_HSA
3L	11037690	3L_11037690_SNP [dm3] 3L_11044590_SNP [dm6]	C	T	3.349e^-5	0.879	INTRON CG43693	TF binding site BDTNP1_TFBS_dl
2L	14109327	2L_14109327_SNP [dm3] 2L_14109327_SNP [dm6]	C	G	3.483e^-5	0.879	UTR_5_PRIME CG15293 UPSTREAM CG15293 DOWNSTREAM CG31769
3R	8527107	3R_8527107_SNP [dm3] 3R_12701385_SNP [dm6]	T	C	3.496e^-5	0.879	INTRON Past1
X	18967493	X_18967493_SNP [dm3] X_19073460_SNP [dm6]	G	T	3.544e^-5	0.879	INTERGENIC
3R	8380171	3R_8380171_SNP [dm3] 3R_12554449_SNP [dm6]	G	A	3.554e^-5	0.879	SYNONYMOUS_CODING Octbeta2R
2L	3378521	2L_3378521_SNP [dm3] 2L_3378521_SNP [dm6]	G	A	3.575e^-5	0.879	UTR_3_PRIME Ptpa
3R	20304791	3R_20304791_SNP [dm3] 3R_24479069_SNP [dm6]	A	T	3.583e^-5	0.879	INTERGENIC
X	21090146	X_21090146_SNP [dm3] X_21219119_SNP [dm6]	T	C	3.730e^-5	0.879	DOWNSTREAM CG32523 INTRON CG32521
2L	3698288	2L_3698288_SNP [dm3] 2L_3698288_SNP [dm6]	G	A	3.744e^-5	0.879	UPSTREAM CG3604 DOWNSTREAM CG10031 INTERGENIC
2L	12943651	2L_12943651_SNP [dm3] 2L_12943651_SNP [dm6]	C	A	3.768e^-5	0.879	INTERGENIC
2L	9611301	2L_9611301_SNP [dm3] 2L_9611301_SNP [dm6]	A	G	3.785e^-5	0.879	SYNONYMOUS_CODING gcm2	TF binding site mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_inv mE1_TFBS_sens
2L	9611386	2L_9611386_SNP [dm3] 2L_9611386_SNP [dm6]	T	C	3.785e^-5	0.879	INTRON gcm2	TF binding site mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_inv mE1_TFBS_sens
3R	6867831	3R_6867831_SNP [dm3] 3R_11042109_SNP [dm6]	G	A	3.922e^-5	0.879	INTRON CG34114
3L	1682162	3L_1682162_SNP [dm3] 3L_1682162_SNP [dm6]	T	A	4.069e^-5	0.879	INTRON CG7991
2L	9612385	2L_9612385_SNP [dm3] 2L_9612385_SNP [dm6]	C	T	4.089e^-5	0.879	SYNONYMOUS_CODING gcm2 UPSTREAM Trx-2	TF binding site BDTNP1_TFBS_dl mE1_TFBS_bab1 mE1_TFBS_cad mE1_TFBS_chinmo mE1_TFBS_HSA mE1_TFBS_zfh1
2L	3494106	2L_3494106_SNP [dm3] 2L_3494106_SNP [dm6]	G	C	4.120e^-5	0.879	UTR_3_PRIME tim
2L	9078590	2L_9078590_SNP [dm3] 2L_9078590_SNP [dm6]	A	T	4.152e^-5	0.879	DOWNSTREAM CG12439 INTERGENIC
2L	11640890	2L_11640890_SNP [dm3] 2L_11640890_SNP [dm6]	C	T	4.169e^-5	0.879	INTERGENIC
2R	18381794	2R_18381794_SNP [dm3] 2R_22494289_SNP [dm6]	G	T	4.178e^-5	0.879	UTR_3_PRIME CG4610 DOWNSTREAM px
2R	9667913	2R_9667913_SNP [dm3] 2R_13780408_SNP [dm6]	T	C	4.207e^-5	0.879	UPSTREAM S-Lap7 INTRON Cpr50Ca
3L	12437125	3L_12437125_SNP [dm3] 3L_12444025_SNP [dm6]	G	A	4.218e^-5	0.879	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_eve mE1_TFBS_HSA
X	1824354	X_1824354_SNP [dm3] X_1930321_SNP [dm6]	C	A	4.253e^-5	0.879	UTR_3_PRIME CG11596
3R	22543916	3R_22543916_SNP [dm3] 3R_26718194_SNP [dm6]	T	C	4.326e^-5	0.879	UPSTREAM CG6425 INTRON CG5484	TF binding site mE1_TFBS_cad mE1_TFBS_chinmo
3R	20304785	3R_20304785_SNP [dm3] 3R_24479063_SNP [dm6]	A	T	4.328e^-5	0.879	INTERGENIC
2L	9614289	2L_9614289_SNP [dm3] 2L_9614289_SNP [dm6]	C	A	4.341e^-5	0.879	INTRON Trx-2	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_prd BDTNP1_TFBS_twi mE1_TFBS_Trl
X	5329994	X_5329994_SNP [dm3] X_5435961_SNP [dm6]	A	C	4.416e^-5	0.879	DOWNSTREAM CR44471 INTERGENIC	TF binding site mE1_TFBS_HSA mE1_TFBS_sbb
3R	23451155	3R_23451155_SNP [dm3] 3R_27625433_SNP [dm6]	C	T	4.501e^-5	0.879	INTRON Tusp & 1 other
2L	14108972	2L_14108972_SNP [dm3] 2L_14108972_SNP [dm6]	A	G	4.510e^-5	0.879	SYNONYMOUS_CODING CG15293 DOWNSTREAM CG31769
2L	9078595	2L_9078595_SNP [dm3] 2L_9078595_SNP [dm6]	A	C	4.522e^-5	0.879	DOWNSTREAM CG12439 INTERGENIC
X	14493016	X_14493016_SNP [dm3] X_14598983_SNP [dm6]	A	G	4.543e^-5	0.879	INTRON CG9413
2L	17943201	2L_17943201_SNP [dm3] 2L_17943201_SNP [dm6]	G	T	4.548e^-5	0.879	INTERGENIC
2R	10089121	2R_10089121_SNP [dm3] 2R_14201616_SNP [dm6]	A	G	4.585e^-5	0.879	SYNONYMOUS_CODING Sox15 UPSTREAM VGAT	TF binding site mE1_TFBS_cad mE1_TFBS_chinmo
X	17220143	X_17220143_SNP [dm3] X_17326110_SNP [dm6]	C	T	4.656e^-5	0.879	INTERGENIC
3R	19889837	3R_19889837_SNP [dm3] 3R_24064115_SNP [dm6]	C	A	4.668e^-5	0.879	DOWNSTREAM 4EHP INTRON 4EHP
X	16607976	X_16607976_SNP [dm3] X_16713943_SNP [dm6]	G	A	4.700e^-5	0.879	SYNONYMOUS_CODING CG13008 DOWNSTREAM CG34325	TF binding site mE1_TFBS_cad
X	14469863	X_14469863_SNP [dm3] X_14575830_SNP [dm6]	A	T	4.727e^-5	0.879	INTERGENIC	TF binding site BDTNP1_TFBS_dl
3R	7115019	3R_7115019_SNP [dm3] 3R_11289297_SNP [dm6]	T	C	4.741e^-5	0.879	INTRON CR31386
2L	9608815	2L_9608815_SNP [dm3] 2L_9608815_SNP [dm6]	A	C	4.759e^-5	0.879	UTR_5_PRIME gcm2	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_Trl

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By genomic position
Variant impact
Gene name

Lifespan_28C phenotype

Phenotype distribution and association to known covariates

QQplot

Manhattan plot

GWAS results

Phenotype distribution and association to known covariates

QQplot

Manhattan plot

GWAS results