DGRPool

GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=1.090e^-1)
Null hypothesis is not rejected (p>0.05).
Interpretation: NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test
No significant result.

Kruskal-Wallis test
No significant result.

PNG PDF

QQplot

PNG PDF

Manhattan plot

GWAS results

2768 significant hits at p-value < 0.001. The 1000 top results are displayed in the table below.

We performed a gene enrichment calculation (Fisher's exact test) of all GWAS-associated genes at p < 0.001. Genesets were taken from two database: the Gene Ontology (GO) and the FlyBase phenotypes. GO enrichment FlyBase phenotype enrichment

Variant impact HIGH MODERATE LOW MODIFIER

Show entries

Search:

Chromosome	Position	ID	Reference	Variant	p-value	FDR_BH	Transcript annotation	Binding site annotation
3L	23765906	3L_23765906_SNP [dm3] 3L_23772806_SNP [dm6]	C	A	3.039e^-8	0.057	INTERGENIC
2R	10628938	2R_10628938_SNP [dm3] 2R_14741433_SNP [dm6]	C	A	1.063e^-7	0.091	INTRON CG12858	TF binding site mE1_TFBS_cad
3L	9132740	3L_9132740_SNP [dm3] 3L_9139640_SNP [dm6]	G	A	1.467e^-7	0.091	INTRON nwk
3L	23438518	3L_23438518_SNP [dm3] 3L_23445418_SNP [dm6]	A	C	2.593e^-7	0.091	INTERGENIC
3L	23446863	3L_23446863_SNP [dm3] 3L_23453763_SNP [dm6]	G	C	2.944e^-7	0.091	INTERGENIC	transposable element FlyBase
3L	23689575	3L_23689575_SNP [dm3] 3L_23696475_SNP [dm6]	G	A	4.116e^-7	0.091	INTERGENIC	transposable element FlyBase
3L	23315613	3L_23315613_SNP [dm3] 3L_23322513_SNP [dm6]	G	A	4.145e^-7	0.091	INTRON alpha-Cat	transposable element FlyBase
3L	23689730	3L_23689730_SNP [dm3] 3L_23696630_SNP [dm6]	C	A	4.386e^-7	0.091	INTERGENIC	transposable element FlyBase
3L	23323540	3L_23323540_SNP [dm3] 3L_23330440_SNP [dm6]	G	C	4.387e^-7	0.091	INTRON alpha-Cat
3L	23395554	3L_23395554_DEL [dm3] 3L_23402454_DEL [dm6]	TGGCGAGCAGCAT...	T	5.300e^-7	0.099	INTERGENIC
3L	23455475	3L_23455475_DEL [dm3] 3L_23462375_DEL [dm6]	TT	T	6.937e^-7	0.107	INTERGENIC	transposable element FlyBase
3L	23322902	3L_23322902_SNP [dm3] 3L_23329802_SNP [dm6]	T	A	7.356e^-7	0.107	UTR_3_PRIME alpha-Cat INTRON alpha-Cat	transposable element FlyBase
3L	14327309	3L_14327309_SNP [dm3] 3L_14334209_SNP [dm6]	G	A	7.442e^-7	0.107	INTRON fz	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_cad
3L	23326140	3L_23326140_DEL [dm3] 3L_23333040_DEL [dm6]	GAGTATGG	G	8.472e^-7	0.114	INTRON alpha-Cat	transposable element FlyBase
3L	23583808	3L_23583808_SNP [dm3] 3L_23590708_SNP [dm6]	C	T	9.361e^-7	0.117	INTRON AGO3
3L	23561494	3L_23561494_SNP [dm3] 3L_23568394_SNP [dm6]	G	A	1.321e^-6	0.127	INTRON AGO3	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
3L	23335266	3L_23335266_SNP [dm3] 3L_23342166_SNP [dm6]	C	A	1.346e^-6	0.127	DOWNSTREAM CG32230 INTRON CG32230
3L	23476346	3L_23476346_SNP [dm3] 3L_23483246_SNP [dm6]	T	A	1.408e^-6	0.127	INTERGENIC	transposable element FlyBase
3L	23780916	3L_23780916_SNP [dm3] 3L_23787816_SNP [dm6]	A	G	1.453e^-6	0.127	DOWNSTREAM CG43968 INTERGENIC	transposable element FlyBase
3L	23272530	3L_23272530_SNP [dm3] 3L_23279430_SNP [dm6]	T	G	1.468e^-6	0.127	INTRON nAChRalpha4	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_prd transposable element FlyBase
3L	23390194	3L_23390194_SNP [dm3] 3L_23397094_SNP [dm6]	A	G	1.487e^-6	0.127	INTERGENIC	transposable element FlyBase
3L	23388036	3L_23388036_SNP [dm3] 3L_23394936_SNP [dm6]	A	T	1.537e^-6	0.127	INTERGENIC
3L	23497091	3L_23497091_SNP [dm3] 3L_23503991_SNP [dm6]	T	G	1.559e^-6	0.127	INTERGENIC
3L	23583809	3L_23583809_SNP [dm3] 3L_23590709_SNP [dm6]	C	A	1.880e^-6	0.132	INTRON AGO3
3L	23447453	3L_23447453_SNP [dm3] 3L_23454353_SNP [dm6]	C	G	1.881e^-6	0.132	INTERGENIC
3L	23329671	3L_23329671_SNP [dm3] 3L_23336571_SNP [dm6]	G	A	1.887e^-6	0.132	INTRON alpha-Cat	transposable element FlyBase
3L	23507917	3L_23507917_SNP [dm3] 3L_23514817_SNP [dm6]	T	G	1.900e^-6	0.132	INTERGENIC	transposable element FlyBase
3L	23323732	3L_23323732_SNP [dm3] 3L_23330632_SNP [dm6]	C	A	2.041e^-6	0.137	INTRON alpha-Cat
3L	23420943	3L_23420943_SNP [dm3] 3L_23427843_SNP [dm6]	A	C	2.171e^-6	0.14	INTERGENIC
3L	23762071	3L_23762071_SNP [dm3] 3L_23768971_SNP [dm6]	T	C	2.299e^-6	0.14	INTERGENIC	TF binding site mE1_TFBS_inv
3L	23603692	3L_23603692_DEL [dm3] 3L_23610592_DEL [dm6]	TA	G	2.310e^-6	0.14	INTRON AGO3	transposable element FlyBase
3L	15391687	3L_15391687_SNP [dm3] 3L_15398587_SNP [dm6]	A	T	2.584e^-6	0.141	INTERGENIC
3L	23449858	3L_23449858_SNP [dm3] 3L_23456758_SNP [dm6]	C	A	2.630e^-6	0.141	INTERGENIC
3L	23574910	3L_23574910_SNP [dm3] 3L_23581810_SNP [dm6]	C	A	2.647e^-6	0.141	INTRON AGO3	transposable element FlyBase
3L	23761760	3L_23761760_DEL [dm3] 3L_23768660_DEL [dm6]	TT	T	2.756e^-6	0.141	INTERGENIC	TF binding site mE1_TFBS_HSA mE1_TFBS_inv
3L	9132739	3L_9132739_SNP [dm3] 3L_9139639_SNP [dm6]	T	C	2.765e^-6	0.141	INTRON nwk
3L	23387786	3L_23387786_SNP [dm3] 3L_23394686_SNP [dm6]	A	T	2.816e^-6	0.141	INTERGENIC
3L	9132751	3L_9132751_INS [dm3] 3L_9139651_INS [dm6]	A	ACTGTCCAGTTTTA...	2.898e^-6	0.141	INTRON nwk
3L	23306706	3L_23306706_SNP [dm3] 3L_23313606_SNP [dm6]	C	A	2.941e^-6	0.141	INTERGENIC	transposable element FlyBase
3L	23584397	3L_23584397_SNP [dm3] 3L_23591297_SNP [dm6]	C	T	3.184e^-6	0.148	INTRON AGO3
3L	9132734	3L_9132734_DEL [dm3] 3L_9139634_DEL [dm6]	GG	G	3.230e^-6	0.148	INTRON nwk
2R	14821695	2R_14821695_SNP [dm3] 2R_18934190_SNP [dm6]	T	A	3.463e^-6	0.152	INTRON sano
3L	23643378	3L_23643378_SNP [dm3] 3L_23650278_SNP [dm6]	G	A	3.475e^-6	0.152	DOWNSTREAM AGO3 INTRON AGO3
2L	9850005	2L_9850005_DEL [dm3] 2L_9850005_DEL [dm6]	GAGTACGTGTGCA...	T	3.877e^-6	0.165	INTRON nAChRalpha6
2R	16307786	2R_16307786_SNP [dm3] 2R_20420281_SNP [dm6]	C	T	4.344e^-6	0.173	INTERGENIC
3R	9840450	3R_9840450_SNP [dm3] 3R_14014728_SNP [dm6]	A	C	4.369e^-6	0.173	INTRON rdx	TF binding site BDTNP1_TFBS_dl
3L	23326727	3L_23326727_SNP [dm3] 3L_23333627_SNP [dm6]	C	G	4.405e^-6	0.173	INTRON alpha-Cat	transposable element FlyBase
3L	23394468	3L_23394468_SNP [dm3] 3L_23401368_SNP [dm6]	C	T	4.428e^-6	0.173	INTERGENIC
3R	5224594	3R_5224594_SNP [dm3] 3R_9398872_SNP [dm6]	C	A	4.550e^-6	0.174	NON_SYNONYMOUS_CODING Or85f DOWNSTREAM CG34117	TF binding site BDTNP1_TFBS_bcd BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_gt BDTNP1_TFBS_Med BDTNP1_TFBS_sna BDTNP1_TFBS_tll BDTNP1_TFBS_twi mE1_TFBS_sens
3L	23627874	3L_23627874_SNP [dm3] 3L_23634774_SNP [dm6]	G	C	5.331e^-6	0.2	INTRON AGO3
3L	9132732	3L_9132732_SNP [dm3] 3L_9139632_SNP [dm6]	A	T	5.534e^-6	0.202	INTRON nwk
2R	17614527	2R_17614527_SNP [dm3] 2R_21727022_SNP [dm6]	C	T	5.596e^-6	0.202	DOWNSTREAM CR44750 INTERGENIC	transposable element FlyBase
3L	23438911	3L_23438911_SNP [dm3] 3L_23445811_SNP [dm6]	A	T	5.982e^-6	0.21	INTERGENIC
3L	16754647	3L_16754647_SNP [dm3] 3L_16761547_SNP [dm6]	T	A	6.057e^-6	0.21	INTERGENIC	TF binding site mE1_TFBS_cnc mE1_TFBS_HSA
3L	23682327	3L_23682327_SNP [dm3] 3L_23689227_SNP [dm6]	C	T	7.087e^-6	0.242	INTRON AGO3	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA transposable element FlyBase
3R	22614850	3R_22614850_SNP [dm3] 3R_26789128_SNP [dm6]	T	C	8.124e^-6	0.27	INTERGENIC
3L	12379676	3L_12379676_SNP [dm3] 3L_12386576_SNP [dm6]	G	T	8.199e^-6	0.27	INTRON Ncc69	TF binding site mE1_TFBS_cnc
3R	8384777	3R_8384777_SNP [dm3] 3R_12559055_SNP [dm6]	G	A	8.630e^-6	0.279	INTRON Octbeta2R
3L	23315019	3L_23315019_SNP [dm3] 3L_23321919_SNP [dm6]	A	T	9.012e^-6	0.284	INTRON alpha-Cat	transposable element FlyBase
3L	16273221	3L_16273221_DEL [dm3] 3L_16280121_DEL [dm6]	ACAAAAGCAACCAACCAACC...	A	9.134e^-6	0.284	UPSTREAM CG13050 & 1 other DOWNSTREAM CG13049 INTERGENIC
3L	23506892	3L_23506892_SNP [dm3] 3L_23513792_SNP [dm6]	T	G	9.323e^-6	0.284	INTERGENIC	transposable element FlyBase
3L	8009720	3L_8009720_SNP [dm3] 3L_8016620_SNP [dm6]	T	C	9.500e^-6	0.284	INTRON nmo
X	8744941	X_8744941_INS [dm3] X_8850908_INS [dm6]	G	GCTG	9.671e^-6	0.284	INTRON CG12075
2R	18947334	2R_18947334_SNP [dm3] 2R_23059811_SNP [dm6]	G	A	9.674e^-6	0.284	SYNONYMOUS_CODING CG44252	TF binding site mE1_TFBS_chinmo mE1_TFBS_HSA
2L	16433604	2L_16433604_SNP [dm3] 2L_16433604_SNP [dm6]	T	C	9.868e^-6	0.285	INTRON CG5888
3R	25543006	3R_25543006_SNP [dm3] 3R_29717284_SNP [dm6]	A	G	1.011e^-5	0.287	UPSTREAM Obp99b INTERGENIC	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_dl mE1_TFBS_disco mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
3L	11776362	3L_11776362_SNP [dm3] 3L_11783262_SNP [dm6]	G	A	1.047e^-5	0.289	SYNONYMOUS_CODING Pi3K68D	TF binding site mE1_TFBS_cad mE1_TFBS_sens
3L	7930430	3L_7930430_SNP [dm3] 3L_7937330_SNP [dm6]	T	C	1.048e^-5	0.289	DOWNSTREAM Srp9 INTERGENIC	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad
3R	11556293	3R_11556293_SNP [dm3] 3R_15730571_SNP [dm6]	T	C	1.073e^-5	0.292	INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
2R	10628914	2R_10628914_SNP [dm3] 2R_14741409_SNP [dm6]	C	A	1.095e^-5	0.293	INTRON CG12858	TF binding site mE1_TFBS_cad
3R	25542987	3R_25542987_SNP [dm3] 3R_29717265_SNP [dm6]	G	T	1.199e^-5	0.31	UPSTREAM Obp99b INTERGENIC	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_dl mE1_TFBS_disco mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
3L	10846523	3L_10846523_SNP [dm3] 3L_10853423_SNP [dm6]	T	G	1.218e^-5	0.31	INTERGENIC	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad mE1_TFBS_HSA
3R	13091040	3R_13091040_SNP [dm3] 3R_17265318_SNP [dm6]	A	C	1.221e^-5	0.31	UTR_5_PRIME CG44257 UPSTREAM beat-IIb
3R	1903057	3R_1903057_SNP [dm3] 3R_6077335_SNP [dm6]	G	A	1.231e^-5	0.31	INTRON Or83c
3L	8717237	3L_8717237_SNP [dm3] 3L_8724137_SNP [dm6]	C	A	1.238e^-5	0.31	SPLICE_SITE_REGION CG6511 INTRON CG6511
3L	23395672	3L_23395672_SNP [dm3] 3L_23402572_SNP [dm6]	G	T	1.276e^-5	0.313	INTERGENIC
2R	9412047	2R_9412047_SNP [dm3] 2R_13524542_SNP [dm6]	A	G	1.286e^-5	0.313	UPSTREAM CG13332 INTRON Vmat
3L	9497778	3L_9497778_SNP [dm3] 3L_9504678_SNP [dm6]	C	A	1.320e^-5	0.314	INTRON path	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_Trl
3R	24915856	3R_24915856_SNP [dm3] 3R_29090134_SNP [dm6]	T	A	1.366e^-5	0.314	INTRON CG11873	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl mE1_TFBS_HSA mE1_TFBS_sens
3L	12337546	3L_12337546_SNP [dm3] 3L_12344446_SNP [dm6]	G	A	1.375e^-5	0.314	INTRON CrzR
3L	23447367	3L_23447367_SNP [dm3] 3L_23454267_SNP [dm6]	G	A	1.389e^-5	0.314	INTERGENIC
3R	16619663	3R_16619663_SNP [dm3] 3R_20793941_SNP [dm6]	T	C	1.391e^-5	0.314	INTRON Syp
3R	11293036	3R_11293036_SNP [dm3] 3R_15467314_SNP [dm6]	C	T	1.398e^-5	0.314	INTRON AdamTS-A
X	13271134	X_13271134_INS [dm3] X_13377101_INS [dm6]	G	GG	1.420e^-5	0.314	INTRON CG1640
3L	23280494	3L_23280494_SNP [dm3] 3L_23287394_SNP [dm6]	A	T	1.452e^-5	0.314	UTR_3_PRIME nAChRalpha4
3L	11776718	3L_11776718_SNP [dm3] 3L_11783618_SNP [dm6]	T	C	1.479e^-5	0.314	SYNONYMOUS_CODING Pi3K68D	TF binding site mE1_TFBS_cad mE1_TFBS_sens
3L	23805246	3L_23805246_SNP [dm3] 3L_23812146_SNP [dm6]	A	T	1.485e^-5	0.314	INTERGENIC	transposable element FlyBase
3R	25542990	3R_25542990_SNP [dm3] 3R_29717268_SNP [dm6]	A	T	1.493e^-5	0.314	UPSTREAM Obp99b INTERGENIC	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_dl mE1_TFBS_disco mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
2L	16433603	2L_16433603_SNP [dm3] 2L_16433603_SNP [dm6]	C	T	1.511e^-5	0.314	INTRON CG5888
X	13271127	X_13271127_SNP [dm3] X_13377094_SNP [dm6]	C	G	1.513e^-5	0.314	INTRON CG1640
2R	18946854	2R_18946854_SNP [dm3] 2R_23059331_SNP [dm6]	T	C	1.524e^-5	0.314	DOWNSTREAM CG44253 INTRON CG44252
3R	25542992	3R_25542992_SNP [dm3] 3R_29717270_SNP [dm6]	C	T	1.545e^-5	0.314	UPSTREAM Obp99b INTERGENIC	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_dl mE1_TFBS_disco mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
3R	25543060	3R_25543060_SNP [dm3] 3R_29717338_SNP [dm6]	C	A	1.558e^-5	0.314	UPSTREAM Obp99b INTERGENIC	regulatory region REDfly_CRMs TF binding site mE1_TFBS_disco mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
3L	23199167	3L_23199167_SNP [dm3] 3L_23206067_SNP [dm6]	T	C	1.632e^-5	0.326	UPSTREAM nAChRalpha4 INTERGENIC	transposable element FlyBase
2L	4928671	2L_4928671_SNP [dm3] 2L_4928671_SNP [dm6]	C	T	1.678e^-5	0.331	UPSTREAM hoe1 INTRON hoe1
3R	25313918	3R_25313918_SNP [dm3] 3R_29488196_SNP [dm6]	T	A	1.711e^-5	0.333	SYNONYMOUS_CODING CG2321	TF binding site mE1_TFBS_chinmo mE1_TFBS_HSA mE1_TFBS_sens
3L	23865459	3L_23865459_SNP [dm3] 3L_23872359_SNP [dm6]	G	C	1.723e^-5	0.333	INTRON CG40470
3L	23657333	3L_23657333_DEL [dm3] 3L_23664233_DEL [dm6]	TGGGCTTT	T	1.773e^-5	0.336	INTRON AGO3	transposable element FlyBase
3L	22044615	3L_22044615_SNP [dm3] 3L_22051515_SNP [dm6]	C	T	1.774e^-5	0.336	INTRON Oct-TyrR
3L	20955927	3L_20955927_SNP [dm3] 3L_20962827_SNP [dm6]	G	C	1.847e^-5	0.346	UTR_3_PRIME CG12983 UPSTREAM CG10587	TF binding site BDTNP1_TFBS_prd mE1_TFBS_sens

Showing 1 to 100 of 1,000 entries

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GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=1.012e^-1)
Null hypothesis is not rejected (p>0.05).
Interpretation: NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test
No significant result.

Kruskal-Wallis test

Covariate	χ²	p-value	Significance
wolba	3.0201	0.0822

PNG PDF

QQplot

PNG PDF

Manhattan plot

GWAS results

2502 significant hits at p-value < 0.001. The 1000 top results are displayed in the table below.

Variant impact HIGH MODERATE LOW MODIFIER

Show entries

Search:

Chromosome	Position	ID	Reference	Variant	p-value	FDR_BH	Transcript annotation	Binding site annotation
3L	9132740	3L_9132740_SNP [dm3] 3L_9139640_SNP [dm6]	G	A	9.338e^-8	0.175	INTRON nwk
X	8744941	X_8744941_INS [dm3] X_8850908_INS [dm6]	G	GCTG	1.407e^-6	0.477	INTRON CG12075
3R	24254519	3R_24254519_INS [dm3] 3R_28428797_INS [dm6]	G	GGTATG	1.451e^-6	0.477	INTRON beat-VI
3L	11776362	3L_11776362_SNP [dm3] 3L_11783262_SNP [dm6]	G	A	1.559e^-6	0.477	SYNONYMOUS_CODING Pi3K68D	TF binding site mE1_TFBS_cad mE1_TFBS_sens
3L	9132751	3L_9132751_INS [dm3] 3L_9139651_INS [dm6]	A	ACTGTCCAGTTTTA...	1.672e^-6	0.477	INTRON nwk
2L	9850005	2L_9850005_DEL [dm3] 2L_9850005_DEL [dm6]	GAGTACGTGTGCA...	T	2.783e^-6	0.477	INTRON nAChRalpha6
3L	23765906	3L_23765906_SNP [dm3] 3L_23772806_SNP [dm6]	C	A	2.900e^-6	0.477	INTERGENIC
3L	23438518	3L_23438518_SNP [dm3] 3L_23445418_SNP [dm6]	A	C	2.901e^-6	0.477	INTERGENIC
2L	4928671	2L_4928671_SNP [dm3] 2L_4928671_SNP [dm6]	C	T	3.060e^-6	0.477	UPSTREAM hoe1 INTRON hoe1
2R	10628938	2R_10628938_SNP [dm3] 2R_14741433_SNP [dm6]	C	A	3.118e^-6	0.477	INTRON CG12858	TF binding site mE1_TFBS_cad
2L	16433604	2L_16433604_SNP [dm3] 2L_16433604_SNP [dm6]	T	C	3.348e^-6	0.477	INTRON CG5888
3L	16751207	3L_16751207_SNP [dm3] 3L_16758107_SNP [dm6]	T	A	3.402e^-6	0.477	INTERGENIC
3L	9132739	3L_9132739_SNP [dm3] 3L_9139639_SNP [dm6]	T	C	3.433e^-6	0.477	INTRON nwk
2L	16433603	2L_16433603_SNP [dm3] 2L_16433603_SNP [dm6]	C	T	3.561e^-6	0.477	INTRON CG5888
3L	23446863	3L_23446863_SNP [dm3] 3L_23453763_SNP [dm6]	G	C	4.063e^-6	0.508	INTERGENIC	transposable element FlyBase
3L	9132734	3L_9132734_DEL [dm3] 3L_9139634_DEL [dm6]	GG	G	4.609e^-6	0.529	INTRON nwk
3L	11776384	3L_11776384_SNP [dm3] 3L_11783284_SNP [dm6]	G	A	4.944e^-6	0.529	SYNONYMOUS_CODING Pi3K68D	TF binding site mE1_TFBS_cad mE1_TFBS_sens
3L	16273221	3L_16273221_DEL [dm3] 3L_16280121_DEL [dm6]	ACAAAAGCAACCAACCAACC...	A	5.243e^-6	0.529	UPSTREAM CG13050 & 1 other DOWNSTREAM CG13049 INTERGENIC
3R	8384777	3R_8384777_SNP [dm3] 3R_12559055_SNP [dm6]	G	A	5.944e^-6	0.529	INTRON Octbeta2R
3L	11776718	3L_11776718_SNP [dm3] 3L_11783618_SNP [dm6]	T	C	5.982e^-6	0.529	SYNONYMOUS_CODING Pi3K68D	TF binding site mE1_TFBS_cad mE1_TFBS_sens
3L	9132732	3L_9132732_SNP [dm3] 3L_9139632_SNP [dm6]	A	T	6.161e^-6	0.529	INTRON nwk
3R	25313918	3R_25313918_SNP [dm3] 3R_29488196_SNP [dm6]	T	A	6.207e^-6	0.529	SYNONYMOUS_CODING CG2321	TF binding site mE1_TFBS_chinmo mE1_TFBS_HSA mE1_TFBS_sens
3L	11776390	3L_11776390_SNP [dm3] 3L_11783290_SNP [dm6]	C	A	7.835e^-6	0.578	SYNONYMOUS_CODING Pi3K68D	TF binding site mE1_TFBS_cad mE1_TFBS_sens
3L	14327309	3L_14327309_SNP [dm3] 3L_14334209_SNP [dm6]	G	A	8.563e^-6	0.578	INTRON fz	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_cad
3L	7930430	3L_7930430_SNP [dm3] 3L_7937330_SNP [dm6]	T	C	8.780e^-6	0.578	DOWNSTREAM Srp9 INTERGENIC	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad
X	4125981	X_4125981_DEL [dm3] X_4231948_DEL [dm6]	TAAACTT	T	8.798e^-6	0.578	INTERGENIC
3R	25543006	3R_25543006_SNP [dm3] 3R_29717284_SNP [dm6]	A	G	9.242e^-6	0.578	UPSTREAM Obp99b INTERGENIC	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_dl mE1_TFBS_disco mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
3R	14826134	3R_14826134_SNP [dm3] 3R_19000412_SNP [dm6]	A	C	9.350e^-6	0.578	INTRON gukh	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_Med BDTNP1_TFBS_shn BDTNP1_TFBS_sna BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_sens
3R	25542987	3R_25542987_SNP [dm3] 3R_29717265_SNP [dm6]	G	T	9.671e^-6	0.578	UPSTREAM Obp99b INTERGENIC	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_dl mE1_TFBS_disco mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
3L	10846523	3L_10846523_SNP [dm3] 3L_10853423_SNP [dm6]	T	G	9.952e^-6	0.578	INTERGENIC	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad mE1_TFBS_HSA
3L	23561494	3L_23561494_SNP [dm3] 3L_23568394_SNP [dm6]	G	A	1.056e^-5	0.578	INTRON AGO3	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
X	11606224	X_11606224_SNP [dm3] X_11712191_SNP [dm6]	G	A	1.070e^-5	0.578	SYNONYMOUS_CODING Amun	TF binding site mE1_TFBS_sens
3L	16754647	3L_16754647_SNP [dm3] 3L_16761547_SNP [dm6]	T	A	1.105e^-5	0.578	INTERGENIC	TF binding site mE1_TFBS_cnc mE1_TFBS_HSA
3L	22047001	3L_22047001_SNP [dm3] 3L_22053901_SNP [dm6]	T	C	1.157e^-5	0.578	INTRON Oct-TyrR
3L	23326140	3L_23326140_DEL [dm3] 3L_23333040_DEL [dm6]	GAGTATGG	G	1.169e^-5	0.578	INTRON alpha-Cat	transposable element FlyBase
3L	13377222	3L_13377222_INS [dm3] 3L_13384122_INS [dm6]	A	AAT	1.172e^-5	0.578	UPSTREAM CG14110 DOWNSTREAM ImpL1 INTERGENIC
3L	8717237	3L_8717237_SNP [dm3] 3L_8724137_SNP [dm6]	C	A	1.172e^-5	0.578	SPLICE_SITE_REGION CG6511 INTRON CG6511
3L	9132767	3L_9132767_SNP [dm3] 3L_9139667_SNP [dm6]	T	C	1.195e^-5	0.578	INTRON nwk
X	17210042	X_17210042_SNP [dm3] X_17316009_SNP [dm6]	A	T	1.293e^-5	0.578	INTRON B-H2	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl mE1_TFBS_cad
2R	4544732	2R_4544732_SNP [dm3] 2R_8657227_SNP [dm6]	T	C	1.295e^-5	0.578	INTRON ptc	TF binding site BDTNP1_TFBS_bcd BDTNP1_TFBS_dl BDTNP1_TFBS_gt BDTNP1_TFBS_hb BDTNP1_TFBS_Med BDTNP1_TFBS_prd BDTNP1_TFBS_sna BDTNP1_TFBS_twi mE1_TFBS_cad
2R	18947334	2R_18947334_SNP [dm3] 2R_23059811_SNP [dm6]	G	A	1.306e^-5	0.578	SYNONYMOUS_CODING CG44252	TF binding site mE1_TFBS_chinmo mE1_TFBS_HSA
3L	7823465	3L_7823465_SNP [dm3] 3L_7830365_SNP [dm6]	T	C	1.327e^-5	0.578	INTRON Pdp1	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
3R	25542990	3R_25542990_SNP [dm3] 3R_29717268_SNP [dm6]	A	T	1.348e^-5	0.578	UPSTREAM Obp99b INTERGENIC	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_dl mE1_TFBS_disco mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
3L	3922024	3L_3922024_SNP [dm3] 3L_3922024_SNP [dm6]	A	T	1.357e^-5	0.578	INTRON Eip63F-1
2L	4928598	2L_4928598_SNP [dm3] 2L_4928598_SNP [dm6]	C	T	1.419e^-5	0.591	UPSTREAM hoe1 INTRON hoe1
3R	25542992	3R_25542992_SNP [dm3] 3R_29717270_SNP [dm6]	C	T	1.458e^-5	0.594	UPSTREAM Obp99b INTERGENIC	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_dl mE1_TFBS_disco mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
3L	10862696	3L_10862696_INS [dm3] 3L_10869596_INS [dm6]	C	CT	1.535e^-5	0.596	UPSTREAM tna INTRON tna
3R	20565182	3R_20565182_SNP [dm3] 3R_24739460_SNP [dm6]	T	G	1.572e^-5	0.596	INTRON tok
3L	10846657	3L_10846657_SNP [dm3] 3L_10853557_SNP [dm6]	G	A	1.590e^-5	0.596	INTERGENIC	TF binding site mE1_TFBS_cad
3R	25543060	3R_25543060_SNP [dm3] 3R_29717338_SNP [dm6]	C	A	1.617e^-5	0.596	UPSTREAM Obp99b INTERGENIC	regulatory region REDfly_CRMs TF binding site mE1_TFBS_disco mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
3L	8009720	3L_8009720_SNP [dm3] 3L_8016620_SNP [dm6]	T	C	1.621e^-5	0.596	INTRON nmo
2R	7574102	2R_7574102_SNP [dm3] 2R_11686597_SNP [dm6]	A	T	1.656e^-5	0.597	UPSTREAM CG13196 INTRON Buffy	regulatory region REDfly_CRMs TF binding site mE1_TFBS_cad
3L	23323540	3L_23323540_SNP [dm3] 3L_23330440_SNP [dm6]	G	C	1.698e^-5	0.597	INTRON alpha-Cat
3L	23395554	3L_23395554_DEL [dm3] 3L_23402454_DEL [dm6]	TGGCGAGCAGCAT...	T	1.730e^-5	0.597	INTERGENIC
3L	23689575	3L_23689575_SNP [dm3] 3L_23696475_SNP [dm6]	G	A	1.768e^-5	0.597	INTERGENIC	transposable element FlyBase
3R	13091040	3R_13091040_SNP [dm3] 3R_17265318_SNP [dm6]	A	C	1.841e^-5	0.597	UTR_5_PRIME CG44257 UPSTREAM beat-IIb
3L	23447453	3L_23447453_SNP [dm3] 3L_23454353_SNP [dm6]	C	G	1.893e^-5	0.597	INTERGENIC
3L	14497176	3L_14497176_SNP [dm3] 3L_14504076_SNP [dm6]	G	C	1.934e^-5	0.597	INTRON bbg
X	4292901	X_4292901_SNP [dm3] X_4398868_SNP [dm6]	A	T	1.980e^-5	0.597	INTRON CR32773
3L	13377103	3L_13377103_DEL [dm3] 3L_13384003_DEL [dm6]	AA	A	1.981e^-5	0.597	UPSTREAM CG14110 DOWNSTREAM ImpL1 INTERGENIC
3R	5224594	3R_5224594_SNP [dm3] 3R_9398872_SNP [dm6]	C	A	2.027e^-5	0.597	NON_SYNONYMOUS_CODING Or85f DOWNSTREAM CG34117	TF binding site BDTNP1_TFBS_bcd BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_gt BDTNP1_TFBS_Med BDTNP1_TFBS_sna BDTNP1_TFBS_tll BDTNP1_TFBS_twi mE1_TFBS_sens
3L	23315613	3L_23315613_SNP [dm3] 3L_23322513_SNP [dm6]	G	A	2.043e^-5	0.597	INTRON alpha-Cat	transposable element FlyBase
3L	9132763	3L_9132763_SNP [dm3] 3L_9139663_SNP [dm6]	G	C	2.111e^-5	0.597	INTRON nwk
X	17210040	X_17210040_SNP [dm3] X_17316007_SNP [dm6]	T	C	2.185e^-5	0.597	INTRON B-H2	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl mE1_TFBS_cad
2R	17130466	2R_17130466_SNP [dm3] 2R_21242961_SNP [dm6]	A	T	2.265e^-5	0.597	INTRON ASPP
2R	9849817	2R_9849817_SNP [dm3] 2R_13962312_SNP [dm6]	C	T	2.302e^-5	0.597	SYNONYMOUS_CODING Cp1	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
2L	15818178	2L_15818178_SNP [dm3] 2L_15818178_SNP [dm6]	T	G	2.379e^-5	0.597	INTERGENIC
3R	13124108	3R_13124108_SNP [dm3] 3R_17298386_SNP [dm6]	T	C	2.394e^-5	0.597	INTERGENIC
2R	17311370	2R_17311370_SNP [dm3] 2R_21423865_SNP [dm6]	C	T	2.402e^-5	0.597	INTRON Sdc
3L	23323732	3L_23323732_SNP [dm3] 3L_23330632_SNP [dm6]	C	A	2.405e^-5	0.597	INTRON alpha-Cat
3R	16611536	3R_16611536_SNP [dm3] 3R_20785814_SNP [dm6]	T	C	2.411e^-5	0.597	INTRON Syp
3L	3922016	3L_3922016_SNP [dm3] 3L_3922016_SNP [dm6]	C	T	2.420e^-5	0.597	INTRON Eip63F-1
2L	3276132	2L_3276132_SNP [dm3] 2L_3276132_SNP [dm6]	T	G	2.480e^-5	0.597	SYNONYMOUS_CODING CG3332	TF binding site mE1_TFBS_cad mE1_TFBS_chinmo
3L	23272530	3L_23272530_SNP [dm3] 3L_23279430_SNP [dm6]	T	G	2.501e^-5	0.597	INTRON nAChRalpha4	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_prd transposable element FlyBase
3L	10706868	3L_10706868_SNP [dm3] 3L_10713768_SNP [dm6]	A	T	2.549e^-5	0.597	INTERGENIC
2L	4928578	2L_4928578_SNP [dm3] 2L_4928578_SNP [dm6]	C	T	2.577e^-5	0.597	UPSTREAM hoe1 INTRON hoe1
3R	19999294	3R_19999294_SNP [dm3] 3R_24173572_SNP [dm6]	G	A	2.597e^-5	0.597	INTRON CG13606
2R	12328310	2R_12328310_DEL [dm3] 2R_16440805_DEL [dm6]	AG	A	2.647e^-5	0.597	INTERGENIC
2L	8187244	2L_8187244_SNP [dm3] 2L_8187244_SNP [dm6]	T	G	2.649e^-5	0.597	SYNONYMOUS_CODING Piezo
2L	12550731	2L_12550731_DEL [dm3] 2L_12550731_DEL [dm6]	AA	A	2.666e^-5	0.597	INTERGENIC
3R	4010876	3R_4010876_SNP [dm3] 3R_8185154_SNP [dm6]	C	G	2.687e^-5	0.597	INTERGENIC
2L	6238737	2L_6238737_SNP [dm3] 2L_6238737_SNP [dm6]	G	T	2.749e^-5	0.597	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_prd mE1_TFBS_HSA mE1_TFBS_sens
3R	1903057	3R_1903057_SNP [dm3] 3R_6077335_SNP [dm6]	G	A	2.768e^-5	0.597	INTRON Or83c
3L	9132742	3L_9132742_SNP [dm3] 3L_9139642_SNP [dm6]	T	C	2.853e^-5	0.597	INTRON nwk
2R	7565545	2R_7565545_SNP [dm3] 2R_11678040_SNP [dm6]	T	C	2.873e^-5	0.597	DOWNSTREAM Tret1-2 INTRON Roc2
3R	25543001	3R_25543001_SNP [dm3] 3R_29717279_SNP [dm6]	G	C	2.896e^-5	0.597	UPSTREAM Obp99b INTERGENIC	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_dl mE1_TFBS_disco mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
3L	3926680	3L_3926680_SNP [dm3] 3L_3926680_SNP [dm6]	C	T	2.919e^-5	0.597	INTRON Eip63F-1
X	8911823	X_8911823_SNP [dm3] X_9017790_SNP [dm6]	T	A	2.983e^-5	0.597	INTRON CR43836 & 1 other
3R	25979387	3R_25979387_SNP [dm3] 3R_30153665_SNP [dm6]	A	T	3.009e^-5	0.597	DOWNSTREAM CG15529 INTRON CG11498	TF binding site BDTNP1_TFBS_dl mE1_TFBS_bab1 mE1_TFBS_cad
3R	8129642	3R_8129642_SNP [dm3] 3R_12303920_SNP [dm6]	C	T	3.010e^-5	0.597	INTERGENIC	TF binding site BDTNP1_TFBS_twi
3L	12379676	3L_12379676_SNP [dm3] 3L_12386576_SNP [dm6]	G	T	3.087e^-5	0.597	INTRON Ncc69	TF binding site mE1_TFBS_cnc
3R	14909472	3R_14909472_SNP [dm3] 3R_19083750_SNP [dm6]	G	A	3.089e^-5	0.597	INTRON cdi	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_chinmo mE1_TFBS_HSA
3L	13377087	3L_13377087_INS [dm3] 3L_13383987_INS [dm6]	T	TATATT	3.100e^-5	0.597	UTR_3_PRIME ImpL1 UPSTREAM CG14110	TF binding site mE1_TFBS_cad
3L	23322902	3L_23322902_SNP [dm3] 3L_23329802_SNP [dm6]	T	A	3.126e^-5	0.597	UTR_3_PRIME alpha-Cat INTRON alpha-Cat	transposable element FlyBase
2L	10639556	2L_10639556_DEL [dm3] 2L_10639556_DEL [dm6]	AA	A	3.133e^-5	0.597	UPSTREAM CG31872 EXON CR45351
3R	6369628	3R_6369628_SNP [dm3] 3R_10543906_SNP [dm6]	G	A	3.142e^-5	0.597	INTRON hth
X	17230634	X_17230634_SNP [dm3] X_17336601_SNP [dm6]	C	T	3.184e^-5	0.597	INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_HSA
X	16436632	X_16436632_SNP [dm3] X_16542599_SNP [dm6]	C	A	3.242e^-5	0.597	UTR_3_PRIME CG9902 DOWNSTREAM CG9902
2R	7574083	2R_7574083_SNP [dm3] 2R_11686578_SNP [dm6]	A	T	3.347e^-5	0.597	UPSTREAM CG13196 INTRON Buffy	regulatory region REDfly_CRMs TF binding site mE1_TFBS_cad
3L	23583808	3L_23583808_SNP [dm3] 3L_23590708_SNP [dm6]	C	T	3.398e^-5	0.597	INTRON AGO3

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StartleRes phenotype

Phenotype distribution and association to known covariates

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Phenotype distribution and association to known covariates

QQplot

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GWAS results