DGRPool

GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=9.145e^-1)
Null hypothesis is not rejected (p>0.05).
Interpretation: NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test

Covariate	p-value	Significance
In_3R_K	0.04709
In_3R_Mo	0.04223

Kruskal-Wallis test

Covariate	χ²	p-value	Significance
In_3R_K	5.5418	0.0626
In_3R_Mo	5.8002	0.055

PNG PDF

QQplot

PNG PDF

Manhattan plot

GWAS results

2443 significant hits at p-value < 0.001. The 1000 top results are displayed in the table below.

We performed a gene enrichment calculation (Fisher's exact test) of all GWAS-associated genes at p < 0.001. Genesets were taken from two database: the Gene Ontology (GO) and the FlyBase phenotypes. GO enrichment FlyBase phenotype enrichment

Variant impact HIGH MODERATE LOW MODIFIER

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Chromosome	Position	ID	Reference	Variant	p-value	FDR_BH	Transcript annotation	Binding site annotation
3R	20790627	3R_20790627_SNP [dm3] 3R_24964905_SNP [dm6]	G	A	5.394e^-7	0.326	INTERGENIC	TF binding site mE1_TFBS_inv
3R	15644548	3R_15644548_SNP [dm3] 3R_19818826_SNP [dm6]	G	A	5.664e^-7	0.326	INTRON bnl	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_prd BDTNP1_TFBS_twi mE1_TFBS_HSA
2R	6334946	2R_6334946_SNP [dm3] 2R_10447441_SNP [dm6]	G	A	6.905e^-7	0.326	INTRON Galphao
3R	15644534	3R_15644534_SNP [dm3] 3R_19818812_SNP [dm6]	G	A	7.992e^-7	0.326	INTRON bnl	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_prd BDTNP1_TFBS_twi mE1_TFBS_HSA
3L	12316489	3L_12316489_SNP [dm3] 3L_12323389_SNP [dm6]	T	A	8.691e^-7	0.326	INTERGENIC
3R	26373792	3R_26373792_SNP [dm3] 3R_30548070_SNP [dm6]	C	T	1.198e^-6	0.347	INTRON tmod
3L	12324441	3L_12324441_SNP [dm3] 3L_12331341_SNP [dm6]	T	A	1.438e^-6	0.347	INTRON CG32105	TF binding site mE1_TFBS_cad mE1_TFBS_HSA
3L	12316555	3L_12316555_DEL [dm3] 3L_12323455_DEL [dm6]	AGTGTATTATAA...	A	1.612e^-6	0.347	INTERGENIC
3L	16388169	3L_16388169_SNP [dm3] 3L_16395069_SNP [dm6]	T	C	1.665e^-6	0.347	SYNONYMOUS_CODING Grp INTRON CG44836	TF binding site mE1_TFBS_HSA
3L	10331313	3L_10331313_SNP [dm3] 3L_10338213_SNP [dm6]	T	C	1.859e^-6	0.349	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_Med BDTNP1_TFBS_sna BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_inv
3R	25839303	3R_25839303_SNP [dm3] 3R_30013581_SNP [dm6]	T	G	2.731e^-6	0.466	INTRON CG7920
3L	1741283	3L_1741283_SNP [dm3] 3L_1741283_SNP [dm6]	G	A	3.175e^-6	0.496	UPSTREAM Gk INTRON Gk
3R	18081003	3R_18081003_SNP [dm3] 3R_22255281_SNP [dm6]	C	G	3.703e^-6	0.534	INTRON SKIP
3R	25219905	3R_25219905_SNP [dm3] 3R_29394183_SNP [dm6]	T	G	4.184e^-6	0.561	INTRON Ptp99A
2L	4658980	2L_4658980_SNP [dm3] 2L_4658980_SNP [dm6]	T	A	5.050e^-6	0.599	INTERGENIC
2R	18974866	2R_18974866_SNP [dm3] 2R_23087343_SNP [dm6]	C	T	5.106e^-6	0.599	SYNONYMOUS_CODING CG13538
3R	16937461	3R_16937461_SNP [dm3] 3R_21111739_SNP [dm6]	C	T	5.809e^-6	0.607	UTR_5_PRIME Rab11 DOWNSTREAM rtet	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_cad mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_jumu mE1_TFBS_run mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_Ubx
3L	12852720	3L_12852720_SNP [dm3] 3L_12859620_SNP [dm6]	C	G	6.194e^-6	0.607	NON_SYNONYMOUS_CODING CG32107
X	12220236	X_12220236_SNP [dm3] X_12326203_SNP [dm6]	C	T	6.380e^-6	0.607	INTRON Ten-a
2R	15783263	2R_15783263_SNP [dm3] 2R_19895758_SNP [dm6]	C	T	6.471e^-6	0.607	INTERGENIC	TF binding site mE1_TFBS_HSA
3L	10267180	3L_10267180_SNP [dm3] 3L_10274080_SNP [dm6]	G	T	7.305e^-6	0.652	NON_SYNONYMOUS_CODING Or67d
2L	15641230	2L_15641230_SNP [dm3] 2L_15641230_SNP [dm6]	A	T	8.525e^-6	0.658	INTERGENIC
2R	7366501	2R_7366501_SNP [dm3] 2R_11478996_SNP [dm6]	G	A	8.849e^-6	0.658	INTRON inv	TF binding site BDTNP1_TFBS_dl
3L	10267179	3L_10267179_SNP [dm3] 3L_10274079_SNP [dm6]	G	T	9.200e^-6	0.658	NON_SYNONYMOUS_CODING Or67d
3R	21085305	3R_21085305_SNP [dm3] 3R_25259583_SNP [dm6]	C	T	9.202e^-6	0.658	SYNONYMOUS_CODING CG11857 DOWNSTREAM Nup358	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_sens
3L	5437901	3L_5437901_SNP [dm3] 3L_5444801_SNP [dm6]	G	A	9.320e^-6	0.658	INTERGENIC
3R	25221542	3R_25221542_SNP [dm3] 3R_29395820_SNP [dm6]	G	A	9.466e^-6	0.658	INTRON Ptp99A
3R	14342975	3R_14342975_SNP [dm3] 3R_18517253_SNP [dm6]	G	A	9.932e^-6	0.665	INTRON fru
3R	12798863	3R_12798863_SNP [dm3] 3R_16973141_SNP [dm6]	A	G	1.080e^-5	0.698	UPSTREAM Abd-B INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_prd
3R	23911489	3R_23911489_SNP [dm3] 3R_28085767_SNP [dm6]	A	C	1.181e^-5	0.728	UTR_3_PRIME CG34362 DOWNSTREAM CG34362 INTRON CG34362	TF binding site BDTNP1_TFBS_twi
X	15579895	X_15579895_SNP [dm3] X_15685862_SNP [dm6]	A	T	1.222e^-5	0.728	NON_SYNONYMOUS_CODING CG15599	TF binding site BDTNP1_TFBS_prd mE1_TFBS_sens
3R	23567387	3R_23567387_SNP [dm3] 3R_27741665_SNP [dm6]	A	G	1.287e^-5	0.728	INTRON Ets98B
3R	12397827	3R_12397827_SNP [dm3] 3R_16572105_SNP [dm6]	C	T	1.300e^-5	0.728	NON_SYNONYMOUS_CODING CG14891 DOWNSTREAM CG42342	TF binding site mE1_TFBS_sens
3R	7059551	3R_7059551_DEL [dm3] 3R_11233829_DEL [dm6]	ACACACA	A	1.320e^-5	0.728	INTRON Arfip	TF binding site mE1_TFBS_cad
2L	3004539	2L_3004539_SNP [dm3] 2L_3004539_SNP [dm6]	C	G	1.429e^-5	0.735	INTRON CG17265	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_prd mE1_TFBS_cad
3L	18296807	3L_18296807_SNP [dm3] 3L_18303707_SNP [dm6]	A	G	1.576e^-5	0.735	SYNONYMOUS_CODING grim	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi
3R	18687667	3R_18687667_SNP [dm3] 3R_22861945_SNP [dm6]	A	G	1.595e^-5	0.735	INTERGENIC
3R	12798325	3R_12798325_SNP [dm3] 3R_16972603_SNP [dm6]	C	T	1.607e^-5	0.735	UPSTREAM Abd-B INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_prd mE1_TFBS_HSA
2L	4659205	2L_4659205_SNP [dm3] 2L_4659205_SNP [dm6]	T	G	1.655e^-5	0.735	INTERGENIC
3R	12800179	3R_12800179_SNP [dm3] 3R_16974457_SNP [dm6]	G	A	1.696e^-5	0.735	UPSTREAM VhaM9.7-d INTERGENIC	TF binding site BDTNP1_TFBS_slp1 mE1_TFBS_HSA
3R	25641019	3R_25641019_SNP [dm3] 3R_29815297_SNP [dm6]	A	G	1.707e^-5	0.735	SYNONYMOUS_CODING Vps16B DOWNSTREAM ca	TF binding site BDTNP1_TFBS_sna mE1_TFBS_cad mE1_TFBS_chinmo mE1_TFBS_HSA
2L	4683959	2L_4683959_SNP [dm3] 2L_4683959_SNP [dm6]	G	A	1.710e^-5	0.735	SYNONYMOUS_CODING Bsg25A INTRON CG11929	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_hb BDTNP1_TFBS_sna BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_sens
2L	8639953	2L_8639953_SNP [dm3] 2L_8639953_SNP [dm6]	A	G	1.724e^-5	0.735	INTRON Sema-1a	TF binding site mE1_TFBS_eve mE1_TFBS_HSA
3L	11345085	3L_11345085_SNP [dm3] 3L_11351985_SNP [dm6]	G	C	1.725e^-5	0.735	INTERGENIC
3R	14054537	3R_14054537_SNP [dm3] 3R_18228815_SNP [dm6]	T	C	1.853e^-5	0.735	DOWNSTREAM Mdh2 INTERGENIC
3R	12827097	3R_12827097_SNP [dm3] 3R_17001375_SNP [dm6]	A	G	1.884e^-5	0.735	SYNONYMOUS_CODING CG16941	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
2R	7039065	2R_7039065_SNP [dm3] 2R_11151560_SNP [dm6]	C	T	1.994e^-5	0.735	INTRON CG13229
3R	22084571	3R_22084571_SNP [dm3] 3R_26258849_SNP [dm6]	G	A	2.002e^-5	0.735	UPSTREAM Ald INTRON Ald	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_inv mE1_TFBS_Trl
3L	16436009	3L_16436009_SNP [dm3] 3L_16442909_SNP [dm6]	C	T	2.111e^-5	0.735	INTRON CG33158 & 1 other
2R	1092947	2R_1092947_SNP [dm3] 2R_5205442_SNP [dm6]	A	G	2.189e^-5	0.735	INTRON Nipped-A
2L	17467937	2L_17467937_SNP [dm3] 2L_17467937_SNP [dm6]	A	C	2.190e^-5	0.735	INTRON BicD	TF binding site mE1_TFBS_inv
3R	19691870	3R_19691870_SNP [dm3] 3R_23866148_SNP [dm6]	A	G	2.228e^-5	0.735	INTRON Pli	TF binding site BDTNP1_TFBS_dl
X	14523392	X_14523392_SNP [dm3] X_14629359_SNP [dm6]	A	T	2.249e^-5	0.735	INTRON NetA	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_Med BDTNP1_TFBS_prd BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
2R	4623998	2R_4623998_DEL [dm3] 2R_8736493_DEL [dm6]	AA	G	2.253e^-5	0.735	UPSTREAM CG42615 INTRON CG8740
3R	27316346	3R_27316346_SNP [dm3] 3R_31490624_SNP [dm6]	C	T	2.262e^-5	0.735	UPSTREAM CR45572 INTERGENIC
2L	2994455	2L_2994455_SNP [dm3] 2L_2994455_SNP [dm6]	G	T	2.272e^-5	0.735	INTRON CG3558	TF binding site BDTNP1_TFBS_sna
3L	9816076	3L_9816076_SNP [dm3] 3L_9822976_SNP [dm6]	C	T	2.275e^-5	0.735	DOWNSTREAM Ilp5 INTRON CG43897
2R	15145286	2R_15145286_SNP [dm3] 2R_19257781_SNP [dm6]	T	G	2.338e^-5	0.735	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_Med BDTNP1_TFBS_sna BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_D mE1_TFBS_HSA mE1_TFBS_sens
3L	14666187	3L_14666187_SNP [dm3] 3L_14673087_SNP [dm6]	G	A	2.421e^-5	0.735	UTR_5_PRIME ome UPSTREAM CG43121 DOWNSTREAM tRNA:M3:70Fa	TF binding site mE1_TFBS_HSA mE1_TFBS_Trl
3L	14859736	3L_14859736_SNP [dm3] 3L_14866636_SNP [dm6]	T	C	2.465e^-5	0.735	SYNONYMOUS_CODING CG17839
2L	7070955	2L_7070955_SNP [dm3] 2L_7070955_SNP [dm6]	G	T	2.534e^-5	0.735	INTRON Pvf2	TF binding site mE1_TFBS_cad
3R	19147068	3R_19147068_SNP [dm3] 3R_23321346_SNP [dm6]	G	T	2.542e^-5	0.735	INTRON pnt	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
3L	11637298	3L_11637298_SNP [dm3] 3L_11644198_SNP [dm6]	T	C	2.575e^-5	0.735	NON_SYNONYMOUS_CODING CG6071
X	12220171	X_12220171_SNP [dm3] X_12326138_SNP [dm6]	A	C	2.668e^-5	0.735	INTRON Ten-a
3R	14959732	3R_14959732_SNP [dm3] 3R_19134010_SNP [dm6]	T	G	2.733e^-5	0.735	SYNONYMOUS_CODING Cyp12a5
X	10066928	X_10066928_SNP [dm3] X_10172895_SNP [dm6]	G	A	2.774e^-5	0.735	INTRON CG43902 & 1 other
3R	13937834	3R_13937834_SNP [dm3] 3R_18112112_SNP [dm6]	C	T	2.790e^-5	0.735	INTRON sr	TF binding site mE1_TFBS_HSA
3R	21533153	3R_21533153_SNP [dm3] 3R_25707431_SNP [dm6]	T	A	2.872e^-5	0.735	SYNONYMOUS_CODING LpR2 INTRON LpR2	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
2R	19620722	2R_19620722_SNP [dm3] 2R_23733199_SNP [dm6]	T	C	2.875e^-5	0.735	UTR_3_PRIME Sesn DOWNSTREAM mir-4979 & 1 other	TF binding site mE1_TFBS_HSA mE1_TFBS_zfh1
3L	14926445	3L_14926445_SNP [dm3] 3L_14933345_SNP [dm6]	G	A	2.889e^-5	0.735	INTRON DCX-EMAP
3R	18882288	3R_18882288_SNP [dm3] 3R_23056566_SNP [dm6]	G	A	2.961e^-5	0.735	INTRON CG17119	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_sna BDTNP1_TFBS_twi mE1_TFBS_HSA
3R	14364898	3R_14364898_INS [dm3] 3R_18539176_INS [dm6]	A	ACCTTTCAT	2.968e^-5	0.735	INTRON fru
2R	15999431	2R_15999431_SNP [dm3] 2R_20111926_SNP [dm6]	T	C	2.983e^-5	0.735	SYNONYMOUS_CODING 18w	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Mad BDTNP1_TFBS_Med BDTNP1_TFBS_sna mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl
3R	15644856	3R_15644856_SNP [dm3] 3R_19819134_SNP [dm6]	A	T	3.079e^-5	0.735	INTRON bnl	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_prd BDTNP1_TFBS_twi mE1_TFBS_HSA
3R	9722580	3R_9722580_SNP [dm3] 3R_13896858_SNP [dm6]	G	T	3.104e^-5	0.735	INTERGENIC	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
3R	15644186	3R_15644186_SNP [dm3] 3R_19818464_SNP [dm6]	T	C	3.107e^-5	0.735	INTRON bnl	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_prd BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_inv mE1_TFBS_sens
3L	5388040	3L_5388040_INS [dm3] 3L_5394940_INS [dm6]	T	TAAT	3.115e^-5	0.735	INTERGENIC
3R	18779740	3R_18779740_SNP [dm3] 3R_22954018_SNP [dm6]	T	A	3.187e^-5	0.735	INTRON klg
3R	26038796	3R_26038796_SNP [dm3] 3R_30213074_SNP [dm6]	T	C	3.256e^-5	0.735	DOWNSTREAM CecB & 1 other EXON Cec2
2R	2852111	2R_2852111_SNP [dm3] 2R_6964606_SNP [dm6]	G	A	3.259e^-5	0.735	INTRON mim & 1 other	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA mE1_TFBS_sens
3R	12370358	3R_12370358_SNP [dm3] 3R_16544636_SNP [dm6]	T	A	3.289e^-5	0.735	INTRON CG42342	TF binding site BDTNP1_TFBS_da
X	5538276	X_5538276_SNP [dm3] X_5644243_SNP [dm6]	G	A	3.360e^-5	0.735	INTRON CG42492
3R	12360144	3R_12360144_SNP [dm3] 3R_16534422_SNP [dm6]	T	C	3.413e^-5	0.735	INTRON CG42342	TF binding site BDTNP1_TFBS_da mE1_TFBS_HSA
3R	26980216	3R_26980216_SNP [dm3] 3R_31154494_SNP [dm6]	C	A	3.472e^-5	0.735	INTRON Gycbeta100B
3L	12411573	3L_12411573_SNP [dm3] 3L_12418473_SNP [dm6]	A	G	3.532e^-5	0.735	UPSTREAM ArfGAP1 INTERGENIC	TF binding site mE1_TFBS_cnc
3R	19018025	3R_19018025_SNP [dm3] 3R_23192303_SNP [dm6]	G	T	3.745e^-5	0.735	INTRON cnc	TF binding site BDTNP1_TFBS_dl mE1_TFBS_sens
X	12220280	X_12220280_SNP [dm3] X_12326247_SNP [dm6]	T	A	3.824e^-5	0.735	INTRON Ten-a
2R	2851580	2R_2851580_SNP [dm3] 2R_6964075_SNP [dm6]	G	A	3.914e^-5	0.735	INTRON mim & 1 other	TF binding site mE1_TFBS_HSA mE1_TFBS_sbb
2L	4659204	2L_4659204_SNP [dm3] 2L_4659204_SNP [dm6]	T	A	3.930e^-5	0.735	INTERGENIC
3R	14432061	3R_14432061_SNP [dm3] 3R_18606339_SNP [dm6]	C	A	3.983e^-5	0.735	INTRON qin & 1 other
2R	1111096	2R_1111096_SNP [dm3] 2R_5223591_SNP [dm6]	A	T	4.066e^-5	0.735	INTRON Nipped-A	TF binding site BDTNP1_TFBS_dl
3R	5965794	3R_5965794_SNP [dm3] 3R_10140072_SNP [dm6]	T	C	4.078e^-5	0.735	UPSTREAM tws DOWNSTREAM TAF1B INTERGENIC	TF binding site mE1_TFBS_Trl
3R	26746465	3R_26746465_SNP [dm3] 3R_30920743_SNP [dm6]	A	G	4.095e^-5	0.735	UPSTREAM CR44041 INTRON Ptx1	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_slp1 BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_Kr mE1_TFBS_sens
3R	21401205	3R_21401205_SNP [dm3] 3R_25575483_SNP [dm6]	G	A	4.121e^-5	0.735	UPSTREAM msi INTRON msi
2L	1735417	2L_1735417_SNP [dm3] 2L_1735417_SNP [dm6]	G	A	4.137e^-5	0.735	INTRON CG17646
2R	2850872	2R_2850872_SNP [dm3] 2R_6963367_SNP [dm6]	C	T	4.169e^-5	0.735	INTRON mim & 1 other
3R	12832233	3R_12832233_SNP [dm3] 3R_17006511_SNP [dm6]	T	C	4.169e^-5	0.735	INTRON Irc
2R	9462616	2R_9462616_SNP [dm3] 2R_13575111_SNP [dm6]	T	A	4.173e^-5	0.735	UPSTREAM CG42808 EXON CR44365	TF binding site BDTNP1_TFBS_dl
3R	7059546	3R_7059546_DEL [dm3] 3R_11233824_DEL [dm6]	AA	A	4.181e^-5	0.735	INTRON Arfip	TF binding site mE1_TFBS_cad
3L	19304631	3L_19304631_SNP [dm3] 3L_19311531_SNP [dm6]	C	A	4.206e^-5	0.735	INTRON pip

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GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=1.328e^-1)
Null hypothesis is not rejected (p>0.05).
Interpretation: NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test

Covariate	p-value	Significance
wolba	0.03456
In_3R_Mo	0.08396

Kruskal-Wallis test

Covariate	χ²	p-value	Significance
wolba	5.2404	0.0221
In_3R_Mo	4.7443	0.0933

PNG PDF

QQplot

PNG PDF

Manhattan plot

GWAS results

2313 significant hits at p-value < 0.001. The 1000 top results are displayed in the table below.

Variant impact HIGH MODERATE LOW MODIFIER

Show entries

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Chromosome	Position	ID	Reference	Variant	p-value	FDR_BH	Transcript annotation	Binding site annotation
3R	22084571	3R_22084571_SNP [dm3] 3R_26258849_SNP [dm6]	G	A	8.381e^-7	0.735	UPSTREAM Ald INTRON Ald	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_inv mE1_TFBS_Trl
3L	7501906	3L_7501906_SNP [dm3] 3L_7508806_SNP [dm6]	T	C	1.754e^-6	0.735	INTERGENIC
3R	20790627	3R_20790627_SNP [dm3] 3R_24964905_SNP [dm6]	G	A	2.299e^-6	0.735	INTERGENIC	TF binding site mE1_TFBS_inv
3R	11096154	3R_11096154_SNP [dm3] 3R_15270432_SNP [dm6]	A	C	2.933e^-6	0.735	UTR_3_PRIME Zip88E & 1 other
3R	21533153	3R_21533153_SNP [dm3] 3R_25707431_SNP [dm6]	T	A	3.061e^-6	0.735	SYNONYMOUS_CODING LpR2 INTRON LpR2	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
2R	4623998	2R_4623998_DEL [dm3] 2R_8736493_DEL [dm6]	AA	G	5.190e^-6	0.735	UPSTREAM CG42615 INTRON CG8740
3R	22067209	3R_22067209_SNP [dm3] 3R_26241487_SNP [dm6]	G	A	5.427e^-6	0.735	INTRON CR42745
2L	2944268	2L_2944268_SNP [dm3] 2L_2944268_SNP [dm6]	G	T	5.559e^-6	0.735	INTRON lilli	TF binding site mE1_TFBS_cad
2L	6352459	2L_6352459_SNP [dm3] 2L_6352459_SNP [dm6]	A	G	5.670e^-6	0.735	SYNONYMOUS_CODING ppk7
3L	15007559	3L_15007559_SNP [dm3] 3L_15014459_SNP [dm6]	T	G	6.354e^-6	0.735	UPSTREAM Reck DOWNSTREAM Sytbeta INTERGENIC	TF binding site BDTNP1_TFBS_dl mE1_TFBS_bab1 mE1_TFBS_HSA
3L	5781185	3L_5781185_SNP [dm3] 3L_5788085_SNP [dm6]	T	A	6.893e^-6	0.735	INTERGENIC
3R	17996679	3R_17996679_SNP [dm3] 3R_22170957_SNP [dm6]	T	C	7.303e^-6	0.735	INTRON SKIP	TF binding site BDTNP1_TFBS_twi mE1_TFBS_cad
3R	21498972	3R_21498972_SNP [dm3] 3R_25673250_SNP [dm6]	C	G	7.851e^-6	0.735	INTRON Lgr3
2R	9638992	2R_9638992_SNP [dm3] 2R_13751487_SNP [dm6]	C	T	8.359e^-6	0.735	INTERGENIC	transposable element FlyBase
3R	22086327	3R_22086327_SNP [dm3] 3R_26260605_SNP [dm6]	C	G	8.449e^-6	0.735	UPSTREAM Ald & 1 other INTRON Ald	TF binding site mE1_TFBS_Trl
3R	23884924	3R_23884924_INS [dm3] 3R_28059202_INS [dm6]	A	AAT	8.710e^-6	0.735	INTRON CG34362
2L	6352468	2L_6352468_SNP [dm3] 2L_6352468_SNP [dm6]	A	C	8.929e^-6	0.735	SYNONYMOUS_CODING ppk7
3R	22088829	3R_22088829_DEL [dm3] 3R_26263107_DEL [dm6]	CCT	C	9.192e^-6	0.735	INTRON CG6154
3R	13637036	3R_13637036_SNP [dm3] 3R_17811314_SNP [dm6]	G	A	9.528e^-6	0.735	UPSTREAM tinc & 1 other INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_inv
3R	22081511	3R_22081511_SNP [dm3] 3R_26255789_SNP [dm6]	A	G	9.593e^-6	0.735	DOWNSTREAM Ald INTRON Ald	TF binding site BDTNP1_TFBS_bcd
3R	26380195	3R_26380195_SNP [dm3] 3R_30554473_SNP [dm6]	G	T	1.038e^-5	0.735	DOWNSTREAM CG34155 INTRON tmod
3R	22092990	3R_22092990_SNP [dm3] 3R_26267268_SNP [dm6]	G	A	1.189e^-5	0.735	INTRON CG6154
3R	21490152	3R_21490152_SNP [dm3] 3R_25664430_SNP [dm6]	C	G	1.210e^-5	0.735	SYNONYMOUS_CODING RASSF8
3R	22079945	3R_22079945_SNP [dm3] 3R_26254223_SNP [dm6]	A	G	1.239e^-5	0.735	UTR_3_PRIME Ald DOWNSTREAM Ald	TF binding site mE1_TFBS_bab1 mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_ttk mE1_TFBS_zfh1
3R	13637022	3R_13637022_SNP [dm3] 3R_17811300_SNP [dm6]	A	C	1.246e^-5	0.735	UPSTREAM tinc & 1 other INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_h mE1_TFBS_HSA mE1_TFBS_inv
3R	17761542	3R_17761542_SNP [dm3] 3R_21935820_SNP [dm6]	T	A	1.280e^-5	0.735	INTERGENIC	TF binding site mE1_TFBS_chinmo mE1_TFBS_HSA
3R	22081344	3R_22081344_SNP [dm3] 3R_26255622_SNP [dm6]	T	C	1.306e^-5	0.735	DOWNSTREAM Ald INTRON Ald	TF binding site BDTNP1_TFBS_bcd
2R	16948672	2R_16948672_SNP [dm3] 2R_21061167_SNP [dm6]	G	A	1.337e^-5	0.735	SYNONYMOUS_CODING mRpL54 UPSTREAM CG15653 & 1 other	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_Ubx
3L	14548724	3L_14548724_SNP [dm3] 3L_14555624_SNP [dm6]	A	T	1.396e^-5	0.735	INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_zfh1
3L	14548733	3L_14548733_SNP [dm3] 3L_14555633_SNP [dm6]	C	T	1.396e^-5	0.735	INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_zfh1
2R	14748910	2R_14748910_SNP [dm3] 2R_18861405_SNP [dm6]	T	C	1.443e^-5	0.735	SYNONYMOUS_CODING Jheh3
2R	13414378	2R_13414378_SNP [dm3] 2R_17526873_SNP [dm6]	T	C	1.469e^-5	0.735	SYNONYMOUS_CODING Patronin INTRON Patronin
3R	26280146	3R_26280146_SNP [dm3] 3R_30454424_SNP [dm6]	C	T	1.580e^-5	0.735	UPSTREAM aralar1 INTRON aralar1
3R	22077642	3R_22077642_SNP [dm3] 3R_26251920_SNP [dm6]	G	A	1.612e^-5	0.735	EXON CR42745
3R	26373792	3R_26373792_SNP [dm3] 3R_30548070_SNP [dm6]	C	T	1.628e^-5	0.735	INTRON tmod
2L	10562564	2L_10562564_SNP [dm3] 2L_10562564_SNP [dm6]	G	T	1.646e^-5	0.735	INTRON Trim9
2R	10575017	2R_10575017_SNP [dm3] 2R_14687512_SNP [dm6]	G	A	1.655e^-5	0.735	INTRON mspo
2L	5742791	2L_5742791_SNP [dm3] 2L_5742791_SNP [dm6]	A	G	1.660e^-5	0.735	INTRON CG11030
3R	5757593	3R_5757593_SNP [dm3] 3R_9931871_SNP [dm6]	A	G	1.693e^-5	0.735	INTRON Glut4EF
3L	15007502	3L_15007502_SNP [dm3] 3L_15014402_SNP [dm6]	G	A	1.700e^-5	0.735	UPSTREAM Reck DOWNSTREAM Sytbeta INTERGENIC	TF binding site mE1_TFBS_bab1 mE1_TFBS_HSA
3R	22079550	3R_22079550_SNP [dm3] 3R_26253828_SNP [dm6]	G	A	1.738e^-5	0.735	DOWNSTREAM CR42745 & 1 other INTERGENIC	TF binding site mE1_TFBS_bab1 mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_ttk mE1_TFBS_zfh1
3L	21397373	3L_21397373_SNP [dm3] 3L_21404273_SNP [dm6]	A	C	1.753e^-5	0.735	INTRON rgn
2L	7177948	2L_7177948_SNP [dm3] 2L_7177948_SNP [dm6]	G	A	1.769e^-5	0.735	EXON CR44613
3R	22090334	3R_22090334_SNP [dm3] 3R_26264612_SNP [dm6]	G	A	1.827e^-5	0.735	INTRON CG6154
3R	22091916	3R_22091916_SNP [dm3] 3R_26266194_SNP [dm6]	T	C	1.830e^-5	0.735	INTRON CG6154
X	3716688	X_3716688_SNP [dm3] X_3822655_SNP [dm6]	T	C	1.886e^-5	0.735	INTRON ec
3L	15007465	3L_15007465_SNP [dm3] 3L_15014365_SNP [dm6]	G	A	1.897e^-5	0.735	UPSTREAM Reck DOWNSTREAM Sytbeta INTERGENIC	TF binding site mE1_TFBS_bab1 mE1_TFBS_HSA
X	2147705	X_2147705_SNP [dm3] X_2253672_SNP [dm6]	C	T	1.920e^-5	0.735	DOWNSTREAM CG3078 INTRON CG3091	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
2L	2944558	2L_2944558_SNP [dm3] 2L_2944558_SNP [dm6]	A	T	2.032e^-5	0.735	INTRON lilli	TF binding site mE1_TFBS_bab1 mE1_TFBS_cad
3R	22089582	3R_22089582_SNP [dm3] 3R_26263860_SNP [dm6]	G	T	2.063e^-5	0.735	INTRON CG6154
3R	13636917	3R_13636917_SNP [dm3] 3R_17811195_SNP [dm6]	A	T	2.095e^-5	0.735	UPSTREAM tinc & 1 other INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA mE1_TFBS_inv
3R	22760097	3R_22760097_SNP [dm3] 3R_26934375_SNP [dm6]	T	A	2.099e^-5	0.735	INTRON sda
2R	6269905	2R_6269905_SNP [dm3] 2R_10382400_SNP [dm6]	C	A	2.202e^-5	0.735	INTRON CG42732	TF binding site mE1_TFBS_sbb
2R	6274744	2R_6274744_SNP [dm3] 2R_10387239_SNP [dm6]	A	G	2.228e^-5	0.735	INTRON CG42732
3R	22140378	3R_22140378_SNP [dm3] 3R_26314656_SNP [dm6]	A	T	2.409e^-5	0.735	INTERGENIC	TF binding site mE1_TFBS_inv
X	3716517	X_3716517_SNP [dm3] X_3822484_SNP [dm6]	T	G	2.452e^-5	0.735	INTRON ec	TF binding site mE1_TFBS_HSA
3R	14975334	3R_14975334_SNP [dm3] 3R_19149612_SNP [dm6]	G	A	2.520e^-5	0.735	SYNONYMOUS_CODING CG5835 DOWNSTREAM CR44107
3R	22092944	3R_22092944_SNP [dm3] 3R_26267222_SNP [dm6]	A	G	2.758e^-5	0.735	INTRON CG6154
2L	2944201	2L_2944201_SNP [dm3] 2L_2944201_SNP [dm6]	T	C	2.766e^-5	0.735	INTRON lilli	TF binding site mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_sbb
3L	6501555	3L_6501555_SNP [dm3] 3L_6508455_SNP [dm6]	G	C	2.779e^-5	0.735	INTRON sfl
3L	4055842	3L_4055842_SNP [dm3] 3L_4055842_SNP [dm6]	T	C	2.805e^-5	0.735	INTRON CG1136
3L	15007580	3L_15007580_SNP [dm3] 3L_15014480_SNP [dm6]	G	A	2.943e^-5	0.735	UPSTREAM Reck DOWNSTREAM Sytbeta INTERGENIC	TF binding site BDTNP1_TFBS_dl mE1_TFBS_bab1 mE1_TFBS_HSA
2R	12879250	2R_12879250_SNP [dm3] 2R_16991745_SNP [dm6]	G	T	2.993e^-5	0.735	INTRON Cbp53E
2L	2513835	2L_2513835_SNP [dm3] 2L_2513835_SNP [dm6]	A	T	3.034e^-5	0.735	INTERGENIC
3R	25497523	3R_25497523_SNP [dm3] 3R_29671801_SNP [dm6]	A	G	3.049e^-5	0.735	UPSTREAM ppk19 DOWNSTREAM ppk30 INTRON Obp99a	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA mE1_TFBS_sens
3L	6233615	3L_6233615_DEL [dm3] 3L_6240515_DEL [dm6]	GA	G	3.103e^-5	0.735	UTR_3_PRIME Mdr65 UPSTREAM CG10226
2R	14496905	2R_14496905_SNP [dm3] 2R_18609400_SNP [dm6]	T	A	3.127e^-5	0.735	INTRON GEFmeso	TF binding site BDTNP1_TFBS_twi mE1_TFBS_HSA
3R	14054537	3R_14054537_SNP [dm3] 3R_18228815_SNP [dm6]	T	C	3.129e^-5	0.735	DOWNSTREAM Mdh2 INTERGENIC
2R	4108546	2R_4108546_SNP [dm3] 2R_8221041_SNP [dm6]	G	A	3.141e^-5	0.735	SYNONYMOUS_CODING LRP1	TF binding site mE1_TFBS_chinmo mE1_TFBS_HSA mE1_TFBS_inv
3R	22089635	3R_22089635_SNP [dm3] 3R_26263913_SNP [dm6]	A	T	3.294e^-5	0.735	INTRON CG6154
2L	8695949	2L_8695949_SNP [dm3] 2L_8695949_SNP [dm6]	G	C	3.324e^-5	0.735	INTRON Hnf4
3R	22088527	3R_22088527_SNP [dm3] 3R_26262805_SNP [dm6]	T	C	3.345e^-5	0.735	UTR_5_PRIME CG6154
2L	10913121	2L_10913121_SNP [dm3] 2L_10913121_SNP [dm6]	T	A	3.368e^-5	0.735	INTERGENIC
2L	13924797	2L_13924797_DEL [dm3] 2L_13924797_DEL [dm6]	ACCTGTG	A	3.407e^-5	0.735	INTRON Ance-3
3R	10109274	3R_10109274_SNP [dm3] 3R_14283552_SNP [dm6]	C	T	3.473e^-5	0.735	INTRON trx	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_Trl
2R	19530539	2R_19530539_SNP [dm3] 2R_23643016_SNP [dm6]	T	C	3.478e^-5	0.735	SYNONYMOUS_CODING retn INTRON retn	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_chinmo
X	1763430	X_1763430_SNP [dm3] X_1869397_SNP [dm6]	G	A	3.528e^-5	0.735	SYNONYMOUS_CODING CG14803 UPSTREAM Pex5	TF binding site mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_ttk mE1_TFBS_Ubx
2R	17809949	2R_17809949_SNP [dm3] 2R_21922444_SNP [dm6]	T	C	3.536e^-5	0.735	INTRON Fili
3R	22140023	3R_22140023_SNP [dm3] 3R_26314301_SNP [dm6]	G	T	3.577e^-5	0.735	INTERGENIC	TF binding site mE1_TFBS_inv
3L	16388169	3L_16388169_SNP [dm3] 3L_16395069_SNP [dm6]	T	C	3.604e^-5	0.735	SYNONYMOUS_CODING Grp INTRON CG44836	TF binding site mE1_TFBS_HSA
3L	11357310	3L_11357310_SNP [dm3] 3L_11364210_SNP [dm6]	G	A	3.625e^-5	0.735	UPSTREAM CR45036 INTRON CG6163
2L	8695951	2L_8695951_SNP [dm3] 2L_8695951_SNP [dm6]	A	C	3.658e^-5	0.735	INTRON Hnf4
3L	12324441	3L_12324441_SNP [dm3] 3L_12331341_SNP [dm6]	T	A	3.688e^-5	0.735	INTRON CG32105	TF binding site mE1_TFBS_cad mE1_TFBS_HSA
3R	21900281	3R_21900281_DEL [dm3] 3R_26074559_DEL [dm6]	AA	A	3.732e^-5	0.735	INTERGENIC
3R	22088880	3R_22088880_SNP [dm3] 3R_26263158_SNP [dm6]	G	A	3.766e^-5	0.735	INTRON CG6154
3R	25742689	3R_25742689_SNP [dm3] 3R_29916967_SNP [dm6]	G	A	3.790e^-5	0.735	SYNONYMOUS_CODING trp UTR_3_PRIME trp
3R	6396389	3R_6396389_SNP [dm3] 3R_10570667_SNP [dm6]	T	C	3.811e^-5	0.735	INTRON hth	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_prd
3L	12852036	3L_12852036_SNP [dm3] 3L_12858936_SNP [dm6]	C	A	3.837e^-5	0.735	NON_SYNONYMOUS_CODING CG32107
2R	7167706	2R_7167706_SNP [dm3] 2R_11280201_SNP [dm6]	C	T	3.875e^-5	0.735	SYNONYMOUS_CODING Vhl UPSTREAM CG9067 DOWNSTREAM CG9062	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_slp1 BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_sens
2L	10513960	2L_10513960_SNP [dm3] 2L_10513960_SNP [dm6]	T	C	3.881e^-5	0.735	INTRON Fatp & 1 other
2R	15009183	2R_15009183_SNP [dm3] 2R_19121678_SNP [dm6]	G	C	3.891e^-5	0.735	UTR_3_PRIME 5-HT1A DOWNSTREAM CG15117	TF binding site mE1_TFBS_kn
3L	6367567	3L_6367567_SNP [dm3] 3L_6374467_SNP [dm6]	T	C	3.897e^-5	0.735	INTERGENIC	TF binding site mE1_TFBS_chinmo mE1_TFBS_HSA mE1_TFBS_sens
3R	20502162	3R_20502162_SNP [dm3] 3R_24676440_SNP [dm6]	A	T	3.956e^-5	0.735	INTRON slo
3R	22082496	3R_22082496_SNP [dm3] 3R_26256774_SNP [dm6]	C	A	4.001e^-5	0.735	INTRON Ald	regulatory region REDfly_CRMs TF binding site BDTNP1_TFBS_bcd BDTNP1_TFBS_hb BDTNP1_TFBS_twi mE1_TFBS_HSA
3R	25742654	3R_25742654_SNP [dm3] 3R_29916932_SNP [dm6]	G	C	4.010e^-5	0.735	INTRON trp
2L	5965552	2L_5965552_SNP [dm3] 2L_5965552_SNP [dm6]	A	G	4.024e^-5	0.735	SYNONYMOUS_CODING CG13992 UPSTREAM psd
2R	6274738	2R_6274738_SNP [dm3] 2R_10387233_SNP [dm6]	A	G	4.083e^-5	0.735	INTRON CG42732
2R	4631880	2R_4631880_SNP [dm3] 2R_8744375_SNP [dm6]	C	T	4.088e^-5	0.735	INTRON CG8740 EXON CR44277
3L	5277835	3L_5277835_INS [dm3] 3L_5284735_INS [dm6]	G	GGCATGGCAAAG...	4.109e^-5	0.735	INTERGENIC
3R	8184983	3R_8184983_SNP [dm3] 3R_12359261_SNP [dm6]	A	T	4.203e^-5	0.735	UPSTREAM CG4115 INTERGENIC

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Food_Intake phenotype

Phenotype distribution and association to known covariates

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Phenotype distribution and association to known covariates

QQplot

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GWAS results