DGRPool

GWAS results were precomputed for all phenotypes using PLINK2 [v2.00a3LM (1 Jul 2021)] and corrected for the 6 main covariates defined in Huang et al., 2014. These covariates are the same than the ones used in the DGRP2 website.

GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=3.591e^-26)
Null Hypothesis is rejected (p<=0.05).
Interpretation: NOT NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test
No significant result.

Kruskal-Wallis test

Covariate	χ²	p-value
wolba	8.9655	0.0028
In_2L_t	165	1.4815e-36
In_2R_NS	12.3893	0.002

PNG PDF

QQplot

PNG PDF

Inversion_2L_t phenotype

Phenotype distribution and association to known covariates

QQplot

Manhattan plot

GWAS results

By genomic position
Variant impact
Gene name

Involved in binding site
Binding site