DGRPool

GWAS results were precomputed for all phenotypes using PLINK2 [v2.00a3LM (1 Jul 2021)] and corrected for the 6 main covariates defined in Huang et al., 2014. These covariates are the same than the ones used in the DGRP2 website.

GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=4.365e^-25)
Null Hypothesis is rejected (p<=0.05).
Interpretation: NOT NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test

Covariate	p-value	Significance
In_3R_K	0.00323

Kruskal-Wallis test

Covariate	χ²	p-value	Significance
wolba	151.2404	9.2866e-35
In_2L_t	10.7955	0.0045

PNG PDF

QQplot

PNG PDF

WolbachiaStatus_PCR phenotype

Phenotype distribution and association to known covariates

QQplot

Manhattan plot

GWAS results

By genomic position
Variant impact
Gene name

Involved in binding site
Binding site