DGRPool

GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=6.778e^-3)
Null Hypothesis is rejected (p<=0.05).
Interpretation: NOT NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test

Covariate	p-value	Significance
In_2L_t	1.169e-07
In_2R_NS	0.005484

Kruskal-Wallis test

Covariate	χ²	p-value	Significance
In_3R_Mo	5.1118	0.0776

PNG PDF

QQplot

PNG PDF

Manhattan plot

GWAS results

2287 significant hits at p-value < 0.001. The 1000 top results are displayed in the table below.

We performed a gene enrichment calculation (Fisher's exact test) of all GWAS-associated genes at p < 0.001. Genesets were taken from two database: the Gene Ontology (GO) and the FlyBase phenotypes. GO enrichment FlyBase phenotype enrichment

Variant impact HIGH MODERATE LOW MODIFIER

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Search:

Chromosome	Position	ID	Reference	Variant	p-value	FDR_BH	Transcript annotation	Binding site annotation
3L	13369826	3L_13369826_SNP [dm3] 3L_13376726_SNP [dm6]	T	G	1.788e^-7	0.2	INTERGENIC
3L	13369904	3L_13369904_SNP [dm3] 3L_13376804_SNP [dm6]	T	A	2.136e^-7	0.2	INTERGENIC
3R	13955423	3R_13955423_SNP [dm3] 3R_18129701_SNP [dm6]	C	T	4.656e^-7	0.265	INTRON sr	TF binding site mE1_TFBS_inv
3R	14873592	3R_14873592_SNP [dm3] 3R_19047870_SNP [dm6]	G	A	5.656e^-7	0.265	INTRON cdi
3L	2724250	3L_2724250_DEL [dm3] 3L_2724250_DEL [dm6]	CACGTCGATGA...	C	7.815e^-7	0.293	INTRON Mrtf
3R	20011585	3R_20011585_SNP [dm3] 3R_24185863_SNP [dm6]	T	A	1.414e^-6	0.415	UPSTREAM CHORD INTERGENIC	TF binding site BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_inv
3L	15990399	3L_15990399_SNP [dm3] 3L_15997299_SNP [dm6]	G	A	1.682e^-6	0.415	INTRON CG5830
3R	20011979	3R_20011979_SNP [dm3] 3R_24186257_SNP [dm6]	C	A	1.869e^-6	0.415	UPSTREAM CHORD INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
X	4422951	X_4422951_DEL [dm3] X_4528918_DEL [dm6]	TT	T	2.145e^-6	0.415	INTRON CR32773
3L	13077790	3L_13077790_SNP [dm3] 3L_13084690_SNP [dm6]	T	C	2.346e^-6	0.415	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_sna BDTNP1_TFBS_twi BDTNP1_TFBS_z mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl
2L	4340935	2L_4340935_SNP [dm3] 2L_4340935_SNP [dm6]	C	T	2.431e^-6	0.415	INTRON Atet
3R	20012063	3R_20012063_SNP [dm3] 3R_24186341_SNP [dm6]	G	T	3.084e^-6	0.482	UPSTREAM CHORD INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
3R	13763779	3R_13763779_SNP [dm3] 3R_17938057_SNP [dm6]	G	A	3.732e^-6	0.482	INTRON cpo
3R	6009157	3R_6009157_SNP [dm3] 3R_10183435_SNP [dm6]	T	C	4.211e^-6	0.482	INTRON CG12814
3L	6254404	3L_6254404_SNP [dm3] 3L_6261304_SNP [dm6]	T	A	4.664e^-6	0.482	UPSTREAM ImpL3 INTRON ImpL3
X	1160710	X_1160710_SNP [dm3] X_1266677_SNP [dm6]	T	G	4.913e^-6	0.482	INTRON Atf3
2L	7041758	2L_7041758_SNP [dm3] 2L_7041758_SNP [dm6]	A	C	5.089e^-6	0.482	UPSTREAM milt INTRON milt	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
2R	9544339	2R_9544339_SNP [dm3] 2R_13656834_SNP [dm6]	T	C	5.289e^-6	0.482	INTRON fas
3L	10896881	3L_10896881_SNP [dm3] 3L_10903781_SNP [dm6]	A	C	5.290e^-6	0.482	INTERGENIC
3R	13652542	3R_13652542_SNP [dm3] 3R_17826820_SNP [dm6]	T	G	5.487e^-6	0.482	INTRON tinc	TF binding site BDTNP1_TFBS_bcd BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_ftz BDTNP1_TFBS_gt BDTNP1_TFBS_hb BDTNP1_TFBS_Med BDTNP1_TFBS_prd BDTNP1_TFBS_sna BDTNP1_TFBS_tll BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
3L	7061557	3L_7061557_SNP [dm3] 3L_7068457_SNP [dm6]	C	T	5.607e^-6	0.482	DOWNSTREAM CG14823 INTRON CG8641 & 1 other
X	5701044	X_5701044_SNP [dm3] X_5807011_SNP [dm6]	C	A	5.810e^-6	0.482	INTERGENIC
X	5701047	X_5701047_MNP [dm3] X_5807014_MNP [dm6]	CATC	TGGA	6.117e^-6	0.482	INTERGENIC
3R	20011829	3R_20011829_SNP [dm3] 3R_24186107_SNP [dm6]	G	A	6.163e^-6	0.482	UPSTREAM CHORD INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_inv
3L	7061550	3L_7061550_SNP [dm3] 3L_7068450_SNP [dm6]	T	G	6.688e^-6	0.502	DOWNSTREAM CG14823 INTRON CG8641 & 1 other
3L	4397995	3L_4397995_SNP [dm3] 3L_4397995_SNP [dm6]	C	A	7.609e^-6	0.51	INTRON slow
3L	6254943	3L_6254943_SNP [dm3] 3L_6261843_SNP [dm6]	C	T	7.822e^-6	0.51	UPSTREAM ImpL3 INTRON ImpL3	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
2R	9544338	2R_9544338_SNP [dm3] 2R_13656833_SNP [dm6]	C	A	8.279e^-6	0.51	INTRON fas
3R	10816056	3R_10816056_SNP [dm3] 3R_14990334_SNP [dm6]	T	C	8.300e^-6	0.51	INTERGENIC
X	780023	X_780023_SNP [dm3] X_885990_SNP [dm6]	A	C	8.330e^-6	0.51	INTRON CG43867	TF binding site BDTNP1_TFBS_da mE1_TFBS_HSA
2L	4340377	2L_4340377_SNP [dm3] 2L_4340377_SNP [dm6]	G	A	8.430e^-6	0.51	INTRON Atet
2L	16011302	2L_16011302_SNP [dm3] 2L_16011302_SNP [dm6]	A	G	9.997e^-6	0.54	INTRON beat-Ic
X	19788153	X_19788153_SNP [dm3] X_19894120_SNP [dm6]	C	T	1.028e^-5	0.54	INTRON Hers	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl
X	4423303	X_4423303_SNP [dm3] X_4529270_SNP [dm6]	T	C	1.086e^-5	0.54	UPSTREAM CG3556 INTRON CR32773
3R	25596408	3R_25596408_SNP [dm3] 3R_29770686_SNP [dm6]	A	T	1.117e^-5	0.54	INTRON kay	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_prd BDTNP1_TFBS_twi BDTNP1_TFBS_z mE1_TFBS_cad mE1_TFBS_HSA
2L	16011399	2L_16011399_INS [dm3] 2L_16011399_INS [dm6]	A	AATCAA	1.122e^-5	0.54	INTRON beat-Ic
3R	20011918	3R_20011918_SNP [dm3] 3R_24186196_SNP [dm6]	C	T	1.126e^-5	0.54	UPSTREAM CHORD INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_inv
2L	17729580	2L_17729580_SNP [dm3] 2L_17729580_SNP [dm6]	T	C	1.131e^-5	0.54	INTRON CadN	TF binding site mE1_TFBS_HSA mE1_TFBS_Trl
2L	16011380	2L_16011380_DEL [dm3] 2L_16011380_DEL [dm6]	CC	C	1.229e^-5	0.54	INTRON beat-Ic
3R	20011887	3R_20011887_SNP [dm3] 3R_24186165_SNP [dm6]	C	T	1.233e^-5	0.54	UPSTREAM CHORD INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_inv
3R	15514382	3R_15514382_SNP [dm3] 3R_19688660_SNP [dm6]	T	G	1.256e^-5	0.54	INTRON Naam	TF binding site mE1_TFBS_HSA mE1_TFBS_inv
X	1616708	X_1616708_SNP [dm3] X_1722675_SNP [dm6]	G	T	1.269e^-5	0.54	INTERGENIC	TF binding site mE1_TFBS_chinmo
X	1160748	X_1160748_SNP [dm3] X_1266715_SNP [dm6]	A	G	1.271e^-5	0.54	INTRON Atf3
3R	3487812	3R_3487812_SNP [dm3] 3R_7662090_SNP [dm6]	G	A	1.280e^-5	0.54	INTRON Nlg1
3R	20011165	3R_20011165_SNP [dm3] 3R_24185443_SNP [dm6]	G	A	1.295e^-5	0.54	UPSTREAM CHORD INTERGENIC	TF binding site BDTNP1_TFBS_twi
3R	20012001	3R_20012001_SNP [dm3] 3R_24186279_SNP [dm6]	T	A	1.400e^-5	0.549	UPSTREAM CHORD INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
3L	13076823	3L_13076823_SNP [dm3] 3L_13083723_SNP [dm6]	A	C	1.401e^-5	0.549	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_Kr mE1_TFBS_sens
3L	13370166	3L_13370166_SNP [dm3] 3L_13377066_SNP [dm6]	T	C	1.404e^-5	0.549	UPSTREAM CG14111 INTERGENIC	TF binding site BDTNP1_TFBS_dl
2L	16011271	2L_16011271_INS [dm3] 2L_16011271_INS [dm6]	T	TATT	1.457e^-5	0.549	INTRON beat-Ic
X	1160711	X_1160711_SNP [dm3] X_1266678_SNP [dm6]	T	C	1.483e^-5	0.549	INTRON Atf3
3L	4397994	3L_4397994_SNP [dm3] 3L_4397994_SNP [dm6]	A	T	1.493e^-5	0.549	INTRON slow
2L	16340681	2L_16340681_SNP [dm3] 2L_16340681_SNP [dm6]	T	A	1.540e^-5	0.556	NON_SYNONYMOUS_CODING CG44405 UPSTREAM CG42266	TF binding site mE1_TFBS_sens
3R	9629265	3R_9629265_SNP [dm3] 3R_13803543_SNP [dm6]	G	A	1.613e^-5	0.567	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
2L	16011277	2L_16011277_SNP [dm3] 2L_16011277_SNP [dm6]	T	G	1.647e^-5	0.567	INTRON beat-Ic
3R	14536450	3R_14536450_SNP [dm3] 3R_18710728_SNP [dm6]	T	C	1.724e^-5	0.567	INTRON VAChT & 1 other
2L	7174366	2L_7174366_SNP [dm3] 2L_7174366_SNP [dm6]	G	T	1.801e^-5	0.567	DOWNSTREAM CR44610 INTERGENIC
2L	1484112	2L_1484112_SNP [dm3] 2L_1484112_SNP [dm6]	A	G	1.942e^-5	0.567	INTERGENIC
2L	10803287	2L_10803287_INS [dm3] 2L_10803287_INS [dm6]	G	GG	2.053e^-5	0.567	UPSTREAM CR44581 DOWNSTREAM Nos INTERGENIC	TF binding site mE1_TFBS_HSA mE1_TFBS_inv
2L	6107755	2L_6107755_SNP [dm3] 2L_6107755_SNP [dm6]	A	T	2.132e^-5	0.567	INTRON stai
3L	6239356	3L_6239356_SNP [dm3] 3L_6246256_SNP [dm6]	C	A	2.168e^-5	0.567	UTR_3_PRIME Best2 UPSTREAM Mdr65
2L	16011249	2L_16011249_SNP [dm3] 2L_16011249_SNP [dm6]	C	T	2.198e^-5	0.567	INTRON beat-Ic
3L	6243027	3L_6243027_SNP [dm3] 3L_6249927_SNP [dm6]	T	A	2.208e^-5	0.567	INTRON Best2
2R	2418422	2R_2418422_SNP [dm3] 2R_6530917_SNP [dm6]	A	G	2.220e^-5	0.567	INTRON jing	TF binding site mE1_TFBS_cad
3L	14512920	3L_14512920_SNP [dm3] 3L_14519820_SNP [dm6]	A	G	2.242e^-5	0.567	UTR_3_PRIME CG4613 INTRON bbg
3L	13083190	3L_13083190_SNP [dm3] 3L_13090090_SNP [dm6]	A	T	2.258e^-5	0.567	UPSTREAM CG11251 INTERGENIC	TF binding site mE1_TFBS_HSA
3L	13082500	3L_13082500_SNP [dm3] 3L_13089400_SNP [dm6]	A	G	2.292e^-5	0.567	SYNONYMOUS_CODING CG11251 DOWNSTREAM CR45749	TF binding site BDTNP1_TFBS_sna mE1_TFBS_cad mE1_TFBS_chinmo mE1_TFBS_HSA mE1_TFBS_sens
2L	5797545	2L_5797545_SNP [dm3] 2L_5797545_SNP [dm6]	T	G	2.364e^-5	0.567	INTRON CG9171
3R	20011166	3R_20011166_SNP [dm3] 3R_24185444_SNP [dm6]	A	G	2.379e^-5	0.567	UPSTREAM CHORD INTERGENIC	TF binding site BDTNP1_TFBS_twi
X	5010054	X_5010054_SNP [dm3] X_5116021_SNP [dm6]	T	A	2.394e^-5	0.567	INTRON rg & 1 other
3R	13767858	3R_13767858_SNP [dm3] 3R_17942136_SNP [dm6]	A	T	2.415e^-5	0.567	INTRON cpo	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
3R	14536372	3R_14536372_SNP [dm3] 3R_18710650_SNP [dm6]	A	G	2.483e^-5	0.567	INTRON VAChT & 1 other
3R	3486706	3R_3486706_SNP [dm3] 3R_7660984_SNP [dm6]	A	T	2.494e^-5	0.567	INTRON Nlg1
2R	9971618	2R_9971618_SNP [dm3] 2R_14084113_SNP [dm6]	G	C	2.503e^-5	0.567	INTRON Prosap
2R	9544345	2R_9544345_SNP [dm3] 2R_13656840_SNP [dm6]	C	G	2.517e^-5	0.567	INTRON fas
3L	6252879	3L_6252879_SNP [dm3] 3L_6259779_SNP [dm6]	G	T	2.560e^-5	0.567	SYNONYMOUS_CODING ImpL3
3L	6254060	3L_6254060_DEL [dm3] 3L_6260960_DEL [dm6]	CT	C	2.560e^-5	0.567	INTRON ImpL3
2R	18679927	2R_18679927_SNP [dm3] 2R_22792422_SNP [dm6]	A	T	2.573e^-5	0.567	INTRON CG42260
3R	3483209	3R_3483209_SNP [dm3] 3R_7657487_SNP [dm6]	T	A	2.601e^-5	0.567	UPSTREAM Nlg1 INTERGENIC
X	1071883	X_1071883_SNP [dm3] X_1177850_SNP [dm6]	C	G	2.644e^-5	0.567	INTERGENIC
2R	10369537	2R_10369537_SNP [dm3] 2R_14482032_SNP [dm6]	C	A	2.671e^-5	0.567	INTRON L	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_D mE1_TFBS_disco mE1_TFBS_HSA mE1_TFBS_jumu mE1_TFBS_sens mE1_TFBS_Trl
X	4869925	X_4869925_SNP [dm3] X_4975892_SNP [dm6]	T	C	2.680e^-5	0.567	INTRON CR44833
2L	13439580	2L_13439580_SNP [dm3] 2L_13439580_SNP [dm6]	A	G	2.708e^-5	0.567	UTR_3_PRIME Tehao DOWNSTREAM Tehao INTRON CG42784 EXON CR45683
3R	13769905	3R_13769905_SNP [dm3] 3R_17944183_SNP [dm6]	A	T	2.723e^-5	0.567	UTR_5_PRIME cpo INTRON cpo	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_z mE1_TFBS_D mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl
3R	25930503	3R_25930503_SNP [dm3] 3R_30104781_SNP [dm6]	A	G	2.763e^-5	0.567	SYNONYMOUS_CODING sima INTRON sima
2R	6752379	2R_6752379_SNP [dm3] 2R_10864874_SNP [dm6]	A	C	2.798e^-5	0.567	INTRON CG30015
3R	20994253	3R_20994253_SNP [dm3] 3R_25168531_SNP [dm6]	G	A	2.803e^-5	0.567	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_prd BDTNP1_TFBS_twi mE1_TFBS_disco mE1_TFBS_HSA
2L	5797679	2L_5797679_SNP [dm3] 2L_5797679_SNP [dm6]	A	T	2.838e^-5	0.567	INTRON CG9171
2L	21377436	2L_21377436_SNP [dm3] 2L_21377436_SNP [dm6]	T	C	2.869e^-5	0.567	UTR_3_PRIME CG8665
3L	13399488	3L_13399488_SNP [dm3] 3L_13406388_SNP [dm6]	T	C	2.877e^-5	0.567	INTERGENIC
3L	21121365	3L_21121365_SNP [dm3] 3L_21128265_SNP [dm6]	T	A	2.885e^-5	0.567	INTRON ko
3L	13142696	3L_13142696_SNP [dm3] 3L_13149596_SNP [dm6]	A	G	2.938e^-5	0.567	INTERGENIC
3L	14529616	3L_14529616_SNP [dm3] 3L_14536516_SNP [dm6]	G	A	2.946e^-5	0.567	UPSTREAM CG43246 & 1 other INTERGENIC
X	719514	X_719514_SNP [dm3] X_825481_SNP [dm6]	A	G	3.048e^-5	0.567	INTRON CG43867	TF binding site BDTNP1_TFBS_z
3L	6253710	3L_6253710_SNP [dm3] 3L_6260610_SNP [dm6]	C	T	3.079e^-5	0.567	SYNONYMOUS_CODING ImpL3
3R	13955844	3R_13955844_SNP [dm3] 3R_18130122_SNP [dm6]	T	A	3.083e^-5	0.567	INTRON sr	TF binding site mE1_TFBS_HSA mE1_TFBS_inv
3R	20012183	3R_20012183_SNP [dm3] 3R_24186461_SNP [dm6]	C	A	3.106e^-5	0.567	UTR_5_PRIME CHORD	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA
2L	11931953	2L_11931953_SNP [dm3] 2L_11931953_SNP [dm6]	C	T	3.146e^-5	0.567	INTERGENIC
2L	1477877	2L_1477877_SNP [dm3] 2L_1477877_SNP [dm6]	T	C	3.178e^-5	0.567	INTERGENIC
X	719664	X_719664_SNP [dm3] X_825631_SNP [dm6]	T	C	3.237e^-5	0.567	INTRON CG43867
3L	13142708	3L_13142708_SNP [dm3] 3L_13149608_SNP [dm6]	C	T	3.250e^-5	0.567	INTERGENIC

Showing 1 to 100 of 1,000 entries

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GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=7.947e^-1)
Null hypothesis is not rejected (p>0.05).
Interpretation: NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test

Covariate	p-value	Significance
In_2L_t	0.0007511
In_2R_NS	0.0215397

Kruskal-Wallis test

Covariate	χ²	p-value	Significance
wolba	4.2768	0.0386
In_2L_t	11.4001	0.0033

PNG PDF

QQplot

PNG PDF

Manhattan plot

GWAS results

2223 significant hits at p-value < 0.001. The 1000 top results are displayed in the table below.

Variant impact HIGH MODERATE LOW MODIFIER

Show entries

Search:

Chromosome	Position	ID	Reference	Variant	p-value	FDR_BH	Transcript annotation	Binding site annotation
2L	18628743	2L_18628743_SNP [dm3] 2L_18628743_SNP [dm6]	A	T	9.158e^-7	0.775	INTRON MESR3	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA mE1_TFBS_Trl
X	15966199	X_15966199_SNP [dm3] X_16072166_SNP [dm6]	G	A	1.088e^-6	0.775	INTRON Nipsnap	TF binding site BDTNP1_TFBS_dl
3R	4215867	3R_4215867_SNP [dm3] 3R_8390145_SNP [dm6]	A	T	2.377e^-6	0.775	INTRON CG45263	TF binding site BDTNP1_TFBS_dl
X	18699488	X_18699488_SNP [dm3] X_18805455_SNP [dm6]	C	T	2.837e^-6	0.775	SYNONYMOUS_CODING Pk17E EXON CR44841	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_bab1 mE1_TFBS_HSA
2L	16797403	2L_16797403_SNP [dm3] 2L_16797403_SNP [dm6]	A	C	3.192e^-6	0.775	SYNONYMOUS_CODING Ugt36Bb	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
3R	7976267	3R_7976267_SNP [dm3] 3R_12150545_SNP [dm6]	A	G	3.356e^-6	0.775	NON_SYNONYMOUS_CODING dpr15
3L	5751610	3L_5751610_SNP [dm3] 3L_5758510_SNP [dm6]	C	T	4.407e^-6	0.775	SYNONYMOUS_CODING Ubp64E	TF binding site mE1_TFBS_cad
2L	18344540	2L_18344540_SNP [dm3] 2L_18344540_SNP [dm6]	G	A	4.451e^-6	0.775	INTRON Fas3
X	15966089	X_15966089_SNP [dm3] X_16072056_SNP [dm6]	C	T	4.962e^-6	0.775	INTRON Nipsnap	TF binding site BDTNP1_TFBS_dl
2R	11708517	2R_11708517_SNP [dm3] 2R_15821012_SNP [dm6]	T	C	5.101e^-6	0.775	NON_SYNONYMOUS_CODING CG33465 INTRON tun	TF binding site mE1_TFBS_bab1
3L	13369826	3L_13369826_SNP [dm3] 3L_13376726_SNP [dm6]	T	G	5.355e^-6	0.775	INTERGENIC
3L	2121363	3L_2121363_SNP [dm3] 3L_2121363_SNP [dm6]	C	G	5.937e^-6	0.775	INTRON zormin	TF binding site BDTNP1_TFBS_twi
3R	23381243	3R_23381243_SNP [dm3] 3R_27555521_SNP [dm6]	A	G	5.954e^-6	0.775	SYNONYMOUS_CODING Klp98A
3L	12708836	3L_12708836_SNP [dm3] 3L_12715736_SNP [dm6]	G	A	6.069e^-6	0.775	INTERGENIC
2R	11709912	2R_11709912_SNP [dm3] 2R_15822407_SNP [dm6]	G	C	6.585e^-6	0.775	INTRON tun	TF binding site BDTNP1_TFBS_da mE1_TFBS_cad mE1_TFBS_chinmo mE1_TFBS_HSA mE1_TFBS_sens
2L	8580408	2L_8580408_SNP [dm3] 2L_8580408_SNP [dm6]	G	T	6.679e^-6	0.775	INTRON Sema-1a
2R	11708516	2R_11708516_SNP [dm3] 2R_15821011_SNP [dm6]	C	T	7.025e^-6	0.775	SYNONYMOUS_CODING CG33465 INTRON tun	TF binding site mE1_TFBS_bab1
3L	13266691	3L_13266691_SNP [dm3] 3L_13273591_SNP [dm6]	G	T	8.811e^-6	0.786	INTRON caps
3R	10873788	3R_10873788_SNP [dm3] 3R_15048066_SNP [dm6]	C	A	9.530e^-6	0.786	INTERGENIC
2L	18323682	2L_18323682_SNP [dm3] 2L_18323682_SNP [dm6]	C	G	9.889e^-6	0.786	INTRON Fas3
2R	11708486	2R_11708486_SNP [dm3] 2R_15820981_SNP [dm6]	T	G	1.094e^-5	0.786	SYNONYMOUS_CODING CG33465 INTRON tun	TF binding site mE1_TFBS_bab1
3R	880864	3R_880864_SNP [dm3] 3R_5055142_SNP [dm6]	G	A	1.145e^-5	0.786	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
2R	16023450	2R_16023450_SNP [dm3] 2R_20135945_SNP [dm6]	G	T	1.188e^-5	0.786	DOWNSTREAM CR44634 INTERGENIC
3L	20263539	3L_20263539_SNP [dm3] 3L_20270439_SNP [dm6]	G	T	1.234e^-5	0.786	INTRON gogo
3L	8838722	3L_8838722_DEL [dm3] 3L_8845622_DEL [dm6]	GG	G	1.265e^-5	0.786	INTRON dally
3L	2096916	3L_2096916_SNP [dm3] 3L_2096916_SNP [dm6]	C	T	1.496e^-5	0.786	SYNONYMOUS_CODING sls	TF binding site mE1_TFBS_cad
3R	1785600	3R_1785600_SNP [dm3] 3R_5959878_SNP [dm6]	A	T	1.573e^-5	0.786	UPSTREAM CG34113 DOWNSTREAM CG11373 INTERGENIC
2L	18441771	2L_18441771_SNP [dm3] 2L_18441771_SNP [dm6]	C	G	1.607e^-5	0.786	UTR_3_PRIME RpS26 DOWNSTREAM RpS26	TF binding site mE1_TFBS_HSA mE1_TFBS_zfh1
3R	26723702	3R_26723702_SNP [dm3] 3R_30897980_SNP [dm6]	C	T	1.692e^-5	0.786	SYNONYMOUS_CODING Cyp4c3
3L	2093487	3L_2093487_SNP [dm3] 3L_2093487_SNP [dm6]	A	T	1.762e^-5	0.786	INTRON sls
X	15966361	X_15966361_SNP [dm3] X_16072328_SNP [dm6]	C	T	1.779e^-5	0.786	INTRON Nipsnap	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
X	18180607	X_18180607_SNP [dm3] X_18286574_SNP [dm6]	C	T	1.780e^-5	0.786	INTERGENIC
3L	15874250	3L_15874250_SNP [dm3] 3L_15881150_SNP [dm6]	C	T	1.802e^-5	0.786	INTRON pHCl
2L	18323688	2L_18323688_SNP [dm3] 2L_18323688_SNP [dm6]	C	T	1.876e^-5	0.786	INTRON Fas3
2L	1036956	2L_1036956_SNP [dm3] 2L_1036956_SNP [dm6]	T	G	1.886e^-5	0.786	UPSTREAM CG4415 INTRON IA-2	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_h mE1_TFBS_HSA
3R	1587504	3R_1587504_SNP [dm3] 3R_5761782_SNP [dm6]	A	G	1.925e^-5	0.786	INTRON CG2082
3L	2121310	3L_2121310_SNP [dm3] 3L_2121310_SNP [dm6]	G	A	2.047e^-5	0.786	INTRON zormin	TF binding site BDTNP1_TFBS_twi
X	15966408	X_15966408_SNP [dm3] X_16072375_SNP [dm6]	T	C	2.080e^-5	0.786	INTRON Nipsnap	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
3L	13393597	3L_13393597_DEL [dm3] 3L_13400497_DEL [dm6]	AATAG	A	2.086e^-5	0.786	INTRON sens	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_sens
3R	25164582	3R_25164582_SNP [dm3] 3R_29338860_SNP [dm6]	C	A	2.122e^-5	0.786	INTERGENIC
2L	16797376	2L_16797376_SNP [dm3] 2L_16797376_SNP [dm6]	G	T	2.126e^-5	0.786	NON_SYNONYMOUS_CODING Ugt36Bb	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
3R	11471576	3R_11471576_SNP [dm3] 3R_15645854_SNP [dm6]	G	T	2.158e^-5	0.786	INTERGENIC	TF binding site BDTNP1_TFBS_da
2L	7073182	2L_7073182_DEL [dm3] 2L_7073182_DEL [dm6]	AA	G	2.184e^-5	0.786	INTRON Pvf2
2L	10133369	2L_10133369_INS [dm3] 2L_10133369_INS [dm6]	C	CGA	2.266e^-5	0.786	INTRON CG44153
X	5540804	X_5540804_SNP [dm3] X_5646771_SNP [dm6]	T	G	2.277e^-5	0.786	INTRON CG42492
3L	12512236	3L_12512236_SNP [dm3] 3L_12519136_SNP [dm6]	T	C	2.288e^-5	0.786	INTRON tral	TF binding site mE1_TFBS_HSA
2L	7440872	2L_7440872_SNP [dm3] 2L_7440872_SNP [dm6]	C	T	2.336e^-5	0.786	START_GAINED CG5973 UTR_5_PRIME CG5973 INTRON CG5973
3L	2537301	3L_2537301_SNP [dm3] 3L_2537301_SNP [dm6]	G	A	2.380e^-5	0.786	UPSTREAM Spn INTRON Spn	TF binding site mE1_TFBS_HSA mE1_TFBS_Trl
2L	18628754	2L_18628754_DEL [dm3] 2L_18628754_DEL [dm6]	TAGGTGATCGAATCT...	T	2.393e^-5	0.786	INTRON MESR3	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_Trl
X	13237948	X_13237948_DEL [dm3] X_13343915_DEL [dm6]	ATT	A	2.398e^-5	0.786	DOWNSTREAM CR45708 INTERGENIC
2L	18340460	2L_18340460_SNP [dm3] 2L_18340460_SNP [dm6]	G	A	2.473e^-5	0.786	INTRON Fas3
X	16561937	X_16561937_SNP [dm3] X_16667904_SNP [dm6]	C	A	2.524e^-5	0.786	DOWNSTREAM CG13012 INTRON r	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_chinmo mE1_TFBS_HSA
X	5969749	X_5969749_SNP [dm3] X_6075716_SNP [dm6]	C	A	2.563e^-5	0.786	UPSTREAM Tsp5D DOWNSTREAM CG4666 INTERGENIC
3R	10873747	3R_10873747_SNP [dm3] 3R_15048025_SNP [dm6]	C	T	2.632e^-5	0.786	INTERGENIC
X	13238047	X_13238047_INS [dm3] X_13344014_INS [dm6]	G	GAGTAAAG	2.650e^-5	0.786	DOWNSTREAM CR45708 INTERGENIC
X	13238055	X_13238055_INS [dm3] X_13344022_INS [dm6]	T	AGAA	2.650e^-5	0.786	DOWNSTREAM CR45708 INTERGENIC
2L	16796049	2L_16796049_INS [dm3] 2L_16796049_INS [dm6]	A	TGAAAAATG	2.681e^-5	0.786	UPSTREAM Ugt36Bb DOWNSTREAM Ugt36Ba INTERGENIC
3L	15874240	3L_15874240_SNP [dm3] 3L_15881140_SNP [dm6]	G	A	2.740e^-5	0.786	INTRON pHCl
3L	2096565	3L_2096565_SNP [dm3] 3L_2096565_SNP [dm6]	C	T	2.782e^-5	0.786	SYNONYMOUS_CODING sls	TF binding site mE1_TFBS_cad mE1_TFBS_sens
X	13238030	X_13238030_SNP [dm3] X_13343997_SNP [dm6]	T	C	2.786e^-5	0.786	DOWNSTREAM CR45708 INTERGENIC
3R	10873748	3R_10873748_SNP [dm3] 3R_15048026_SNP [dm6]	C	T	2.801e^-5	0.786	INTERGENIC
2L	18323697	2L_18323697_SNP [dm3] 2L_18323697_SNP [dm6]	C	A	2.905e^-5	0.786	INTRON Fas3
3R	21505012	3R_21505012_SNP [dm3] 3R_25679290_SNP [dm6]	C	A	2.939e^-5	0.786	UTR_3_PRIME CG5039 & 1 other UPSTREAM CG4730	TF binding site mE1_TFBS_sens
3L	13393602	3L_13393602_INS [dm3] 3L_13400502_INS [dm6]	T	TTAAGAATC	2.976e^-5	0.786	INTRON sens	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_sens
2L	7165884	2L_7165884_SNP [dm3] 2L_7165884_SNP [dm6]	A	C	3.072e^-5	0.786	INTERGENIC
X	16472452	X_16472452_SNP [dm3] X_16578419_SNP [dm6]	G	A	3.173e^-5	0.786	INTRON CanA-14F
3R	21023021	3R_21023021_SNP [dm3] 3R_25197299_SNP [dm6]	G	C	3.175e^-5	0.786	DOWNSTREAM CG13653 & 1 other INTERGENIC
3R	11523851	3R_11523851_SNP [dm3] 3R_15698129_SNP [dm6]	T	G	3.184e^-5	0.786	UPSTREAM CR45636 DOWNSTREAM CG5399 & 1 other INTERGENIC
X	13238015	X_13238015_SNP [dm3] X_13343982_SNP [dm6]	T	G	3.258e^-5	0.786	DOWNSTREAM CR45708 INTERGENIC
3L	5799379	3L_5799379_SNP [dm3] 3L_5806279_SNP [dm6]	T	C	3.315e^-5	0.786	DOWNSTREAM CG42272 INTRON S6k	TF binding site BDTNP1_TFBS_bcd BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_prd BDTNP1_TFBS_twi
2R	3477424	2R_3477424_SNP [dm3] 2R_7589919_SNP [dm6]	A	G	3.342e^-5	0.786	UPSTREAM scra INTRON CG1360	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
3L	8011131	3L_8011131_SNP [dm3] 3L_8018031_SNP [dm6]	T	A	3.355e^-5	0.786	INTRON nmo
3R	8188356	3R_8188356_SNP [dm3] 3R_12362634_SNP [dm6]	A	G	3.369e^-5	0.786	SYNONYMOUS_CODING CG4115 UPSTREAM snmRNA:419
2R	6061185	2R_6061185_SNP [dm3] 2R_10173680_SNP [dm6]	G	A	3.379e^-5	0.786	INTRON KCNQ
X	6261382	X_6261382_SNP [dm3] X_6367349_SNP [dm6]	G	T	3.432e^-5	0.786	INTRON Marf
3L	16656882	3L_16656882_SNP [dm3] 3L_16663782_SNP [dm6]	C	T	3.494e^-5	0.786	INTRON Galphaf	TF binding site mE1_TFBS_cad
X	13238012	X_13238012_SNP [dm3] X_13343979_SNP [dm6]	C	T	3.499e^-5	0.786	DOWNSTREAM CR45708 INTERGENIC
3R	21411135	3R_21411135_SNP [dm3] 3R_25585413_SNP [dm6]	T	C	3.568e^-5	0.786	INTRON msi
3R	22156572	3R_22156572_SNP [dm3] 3R_26330850_SNP [dm6]	C	T	3.576e^-5	0.786	INTRON CG33970
3R	458350	3R_458350_SNP [dm3] 3R_4632628_SNP [dm6]	A	G	3.648e^-5	0.786	UTR_3_PRIME 5-HT2A INTRON 5-HT2A	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_HSA
2L	759608	2L_759608_SNP [dm3] 2L_759608_SNP [dm6]	C	A	3.666e^-5	0.786	INTRON GABA-B-R3
3R	419144	3R_419144_SNP [dm3] 3R_4593422_SNP [dm6]	C	T	3.836e^-5	0.786	INTERGENIC
3L	18145889	3L_18145889_DEL [dm3] 3L_18152789_DEL [dm6]	ATTTAAAAAAATATATAAAT...	A	3.901e^-5	0.786	INTRON CG7330
X	13237987	X_13237987_SNP [dm3] X_13343954_SNP [dm6]	T	G	3.989e^-5	0.786	DOWNSTREAM CR45708 INTERGENIC
2L	16800969	2L_16800969_SNP [dm3] 2L_16800969_SNP [dm6]	C	T	4.022e^-5	0.786	SYNONYMOUS_CODING Ugt36Bc	TF binding site mE1_TFBS_cad mE1_TFBS_HSA
2L	18628777	2L_18628777_DEL [dm3] 2L_18628777_DEL [dm6]	AA	A	4.055e^-5	0.786	INTRON MESR3	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_HSA mE1_TFBS_Trl
3L	13393580	3L_13393580_SNP [dm3] 3L_13400480_SNP [dm6]	A	G	4.057e^-5	0.786	INTRON sens	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_sens
3L	8762034	3L_8762034_SNP [dm3] 3L_8768934_SNP [dm6]	C	A	4.069e^-5	0.786	INTRON Fhos
2L	16795979	2L_16795979_SNP [dm3] 2L_16795979_SNP [dm6]	A	G	4.108e^-5	0.786	UTR_3_PRIME Ugt36Ba UPSTREAM Ugt36Bb DOWNSTREAM Ugt36Ba
X	13238014	X_13238014_SNP [dm3] X_13343981_SNP [dm6]	C	T	4.132e^-5	0.786	DOWNSTREAM CR45708 INTERGENIC
3R	13763779	3R_13763779_SNP [dm3] 3R_17938057_SNP [dm6]	G	A	4.148e^-5	0.786	INTRON cpo
X	7424473	X_7424473_SNP [dm3] X_7530440_SNP [dm6]	G	T	4.282e^-5	0.786	INTRON CG32719	regulatory region REDfly_CRMs
3L	12512206	3L_12512206_SNP [dm3] 3L_12519106_SNP [dm6]	A	T	4.309e^-5	0.786	INTRON tral	TF binding site mE1_TFBS_HSA
2L	16220378	2L_16220378_SNP [dm3] 2L_16220378_SNP [dm6]	T	A	4.345e^-5	0.786	INTERGENIC
2L	5302341	2L_5302341_SNP [dm3] 2L_5302341_SNP [dm6]	G	A	4.349e^-5	0.786	INTRON vri
X	8380626	X_8380626_SNP [dm3] X_8486593_SNP [dm6]	A	C	4.352e^-5	0.786	NON_SYNONYMOUS_CODING otu	TF binding site mE1_TFBS_chinmo
3L	14062773	3L_14062773_SNP [dm3] 3L_14069673_SNP [dm6]	A	G	4.366e^-5	0.786	INTRON CG32138
2R	18832609	2R_18832609_SNP [dm3] 2R_22945086_SNP [dm6]	G	A	4.391e^-5	0.786	NON_SYNONYMOUS_CODING CG42694	TF binding site mE1_TFBS_sens
3L	2724250	3L_2724250_DEL [dm3] 3L_2724250_DEL [dm6]	CACGTCGATGA...	C	4.394e^-5	0.786	INTRON Mrtf
3R	20425479	3R_20425479_SNP [dm3] 3R_24599757_SNP [dm6]	A	T	4.413e^-5	0.786	INTRON mld	TF binding site BDTNP1_TFBS_prd mE1_TFBS_HSA

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By genomic position
Variant impact
Gene name

mn_AlcoholTolerance phenotype

Phenotype distribution and association to known covariates

QQplot

Manhattan plot

GWAS results

Phenotype distribution and association to known covariates

QQplot

Manhattan plot

GWAS results