DGRPool

GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=9.043e^-1)
Null hypothesis is not rejected (p>0.05).
Interpretation: NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test

Covariate	p-value	Significance
In_3R_K	0.06857

Kruskal-Wallis test
No significant result.

PNG PDF

QQplot

PNG PDF

Manhattan plot

GWAS results

2131 significant hits at p-value < 0.001. The 1000 top results are displayed in the table below.

We performed a gene enrichment calculation (Fisher's exact test) of all GWAS-associated genes at p < 0.001. Genesets were taken from two database: the Gene Ontology (GO) and the FlyBase phenotypes. GO enrichment FlyBase phenotype enrichment

Variant impact HIGH MODERATE LOW MODIFIER

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Chromosome	Position	ID	Reference	Variant	p-value	FDR_BH	Transcript annotation	Binding site annotation
2L	9762848	2L_9762848_SNP [dm3] 2L_9762848_SNP [dm6]	A	G	3.391e^-7	0.218	UPSTREAM und DOWNSTREAM zf30C INTRON Taf11	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad mE1_TFBS_HSA
3L	6765765	3L_6765765_SNP [dm3] 3L_6772665_SNP [dm6]	C	T	5.179e^-7	0.218	INTERGENIC
2L	9762889	2L_9762889_SNP [dm3] 2L_9762889_SNP [dm6]	G	C	5.212e^-7	0.218	UPSTREAM und DOWNSTREAM zf30C INTRON Taf11	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad mE1_TFBS_HSA
2L	9763025	2L_9763025_SNP [dm3] 2L_9763025_SNP [dm6]	C	T	6.230e^-7	0.218	SYNONYMOUS_CODING Taf11 UPSTREAM und DOWNSTREAM zf30C	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad
2L	9762822	2L_9762822_SNP [dm3] 2L_9762822_SNP [dm6]	C	A	6.712e^-7	0.218	SYNONYMOUS_CODING Taf11 UPSTREAM und DOWNSTREAM zf30C	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad mE1_TFBS_HSA
2L	4396992	2L_4396992_SNP [dm3] 2L_4396992_SNP [dm6]	C	T	6.970e^-7	0.218	SYNONYMOUS_CODING l_2_k05819
2L	9762947	2L_9762947_SNP [dm3] 2L_9762947_SNP [dm6]	C	T	8.148e^-7	0.218	SYNONYMOUS_CODING Taf11 UPSTREAM und DOWNSTREAM zf30C	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad
X	14902643	X_14902643_SNP [dm3] X_15008610_SNP [dm6]	C	T	1.215e^-6	0.285	UTR_3_PRIME eag	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
2L	4396876	2L_4396876_SNP [dm3] 2L_4396876_SNP [dm6]	G	A	2.079e^-6	0.405	SYNONYMOUS_CODING l_2_k05819
X	18146308	X_18146308_SNP [dm3] X_18252275_SNP [dm6]	A	T	2.157e^-6	0.405	INTERGENIC	TF binding site mE1_TFBS_HSA
3R	9068891	3R_9068891_SNP [dm3] 3R_13243169_SNP [dm6]	A	G	2.421e^-6	0.413	INTRON Ace
3L	6766028	3L_6766028_SNP [dm3] 3L_6772928_SNP [dm6]	G	A	3.052e^-6	0.477	INTERGENIC
3L	14106199	3L_14106199_SNP [dm3] 3L_14113099_SNP [dm6]	G	A	3.688e^-6	0.532	SYNONYMOUS_CODING Sox21b
2L	8073539	2L_8073539_SNP [dm3] 2L_8073539_SNP [dm6]	T	C	7.424e^-6	0.8	SYNONYMOUS_CODING Trf UPSTREAM MED20 DOWNSTREAM Mcr	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA mE1_TFBS_sens
2R	9557636	2R_9557636_SNP [dm3] 2R_13670131_SNP [dm6]	G	A	7.457e^-6	0.8	SYNONYMOUS_CODING CG18368 INTRON fas
2R	6722174	2R_6722174_SNP [dm3] 2R_10834669_SNP [dm6]	C	A	7.490e^-6	0.8	UPSTREAM CG12344 INTRON CG12344
3R	13565050	3R_13565050_SNP [dm3] 3R_17739328_SNP [dm6]	T	A	7.595e^-6	0.8	UPSTREAM TyrRII INTRON TyrRII
2L	9763076	2L_9763076_SNP [dm3] 2L_9763076_SNP [dm6]	C	T	7.676e^-6	0.8	SYNONYMOUS_CODING Taf11 UPSTREAM und DOWNSTREAM zf30C	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad
3L	17783225	3L_17783225_SNP [dm3] 3L_17790125_SNP [dm6]	A	C	8.619e^-6	0.8	DOWNSTREAM CG42815 INTERGENIC
3R	9070158	3R_9070158_SNP [dm3] 3R_13244436_SNP [dm6]	A	G	8.790e^-6	0.8	INTRON Ace
3L	5444498	3L_5444498_SNP [dm3] 3L_5451398_SNP [dm6]	A	G	9.773e^-6	0.8	INTERGENIC
2R	9772188	2R_9772188_SNP [dm3] 2R_13884683_SNP [dm6]	G	A	1.042e^-5	0.8	SYNONYMOUS_CODING shot INTRON shot	TF binding site mE1_TFBS_cad mE1_TFBS_chinmo
2L	9762869	2L_9762869_SNP [dm3] 2L_9762869_SNP [dm6]	T	G	1.147e^-5	0.8	UPSTREAM und DOWNSTREAM zf30C INTRON Taf11	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad mE1_TFBS_HSA
3R	8686746	3R_8686746_SNP [dm3] 3R_12861024_SNP [dm6]	C	T	1.164e^-5	0.8	INTERGENIC
2L	4398264	2L_4398264_SNP [dm3] 2L_4398264_SNP [dm6]	C	T	1.207e^-5	0.8	SYNONYMOUS_CODING l_2_k05819	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
2L	9769209	2L_9769209_SNP [dm3] 2L_9769209_SNP [dm6]	A	G	1.232e^-5	0.8	SYNONYMOUS_CODING CG17633 DOWNSTREAM CG4017 INTRON ppk18	TF binding site mE1_TFBS_cad mE1_TFBS_HSA
2R	18272722	2R_18272722_SNP [dm3] 2R_22385217_SNP [dm6]	A	T	1.248e^-5	0.8	INTRON CG13506
2L	4397271	2L_4397271_SNP [dm3] 2L_4397271_SNP [dm6]	C	T	1.262e^-5	0.8	SYNONYMOUS_CODING l_2_k05819
2R	6757322	2R_6757322_SNP [dm3] 2R_10869817_SNP [dm6]	C	T	1.298e^-5	0.8	INTRON CG30015
3L	14107937	3L_14107937_SNP [dm3] 3L_14114837_SNP [dm6]	G	A	1.390e^-5	0.8	INTRON Sox21b
3L	17678020	3L_17678020_SNP [dm3] 3L_17684920_SNP [dm6]	C	T	1.417e^-5	0.8	INTERGENIC
2L	2531422	2L_2531422_SNP [dm3] 2L_2531422_SNP [dm6]	A	C	1.427e^-5	0.8	INTERGENIC
2R	6721973	2R_6721973_SNP [dm3] 2R_10834468_SNP [dm6]	C	A	1.541e^-5	0.8	UPSTREAM CG12344 INTRON CG12344
2L	8073593	2L_8073593_SNP [dm3] 2L_8073593_SNP [dm6]	G	A	1.580e^-5	0.8	SYNONYMOUS_CODING Trf UPSTREAM MED20 DOWNSTREAM Mcr	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA
2R	4853327	2R_4853327_SNP [dm3] 2R_8965822_SNP [dm6]	T	G	1.589e^-5	0.8	INTRON CG8216
3L	17677840	3L_17677840_SNP [dm3] 3L_17684740_SNP [dm6]	T	A	1.598e^-5	0.8	INTERGENIC
3L	8215472	3L_8215472_SNP [dm3] 3L_8222372_SNP [dm6]	T	G	1.716e^-5	0.8	INTRON CG13678
X	5303337	X_5303337_SNP [dm3] X_5409304_SNP [dm6]	T	A	1.727e^-5	0.8	INTRON NAAT1	TF binding site BDTNP1_TFBS_twi
2R	4852907	2R_4852907_SNP [dm3] 2R_8965402_SNP [dm6]	C	G	1.759e^-5	0.8	SYNONYMOUS_CODING CG8216
2L	9654879	2L_9654879_SNP [dm3] 2L_9654879_SNP [dm6]	C	A	1.787e^-5	0.8	NON_SYNONYMOUS_CODING Apoltp	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
3L	13127262	3L_13127262_SNP [dm3] 3L_13134162_SNP [dm6]	G	T	1.804e^-5	0.8	INTERGENIC	TF binding site BDTNP1_TFBS_dl
3L	1709266	3L_1709266_INS [dm3] 3L_1709266_INS [dm6]	G	GCG	1.834e^-5	0.8	INTRON CG7991	TF binding site mE1_TFBS_chinmo mE1_TFBS_inv
3L	2660717	3L_2660717_SNP [dm3] 3L_2660717_SNP [dm6]	C	T	1.922e^-5	0.8	UTR_3_PRIME CG33233 UPSTREAM CG33234 INTRON Fife & 1 other
2L	9769383	2L_9769383_SNP [dm3] 2L_9769383_SNP [dm6]	A	G	1.926e^-5	0.8	SYNONYMOUS_CODING CG17633 DOWNSTREAM CG4017 INTRON ppk18	TF binding site mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_sens
2R	17735433	2R_17735433_DEL [dm3] 2R_21847928_DEL [dm6]	GCTAAT	G	2.053e^-5	0.8	DOWNSTREAM tRNA:CR30406 INTERGENIC
3R	7589637	3R_7589637_SNP [dm3] 3R_11763915_SNP [dm6]	T	A	2.097e^-5	0.8	UTR_5_PRIME Lk6	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_Med BDTNP1_TFBS_prd BDTNP1_TFBS_twi BDTNP1_TFBS_z mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Trl
2L	4397277	2L_4397277_SNP [dm3] 2L_4397277_SNP [dm6]	A	C	2.105e^-5	0.8	SYNONYMOUS_CODING l_2_k05819
2R	9557630	2R_9557630_SNP [dm3] 2R_13670125_SNP [dm6]	G	A	2.182e^-5	0.8	SYNONYMOUS_CODING CG18368 INTRON fas
3L	14104076	3L_14104076_SNP [dm3] 3L_14110976_SNP [dm6]	G	A	2.200e^-5	0.8	INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_hb mE1_TFBS_bab1 mE1_TFBS_HSA mE1_TFBS_zfh1
2R	16606406	2R_16606406_SNP [dm3] 2R_20718901_SNP [dm6]	A	G	2.202e^-5	0.8	INTRON dpr	TF binding site mE1_TFBS_inv
2L	8073572	2L_8073572_SNP [dm3] 2L_8073572_SNP [dm6]	A	C	2.236e^-5	0.8	SYNONYMOUS_CODING Trf UPSTREAM MED20 DOWNSTREAM Mcr	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA
2L	17413926	2L_17413926_SNP [dm3] 2L_17413926_SNP [dm6]	T	A	2.295e^-5	0.8	SYNONYMOUS_CODING Dif DOWNSTREAM CG15141 & 1 other
2L	9767929	2L_9767929_SNP [dm3] 2L_9767929_SNP [dm6]	G	A	2.508e^-5	0.8	SYNONYMOUS_CODING CG4017 INTRON ppk18
3L	3104377	3L_3104377_SNP [dm3] 3L_3104377_SNP [dm6]	G	A	2.525e^-5	0.8	INTRON Cht7
3R	17761855	3R_17761855_SNP [dm3] 3R_21936133_SNP [dm6]	G	A	2.592e^-5	0.8	INTERGENIC
2L	9763142	2L_9763142_SNP [dm3] 2L_9763142_SNP [dm6]	T	C	2.626e^-5	0.8	SYNONYMOUS_CODING Taf11 UPSTREAM und DOWNSTREAM zf30C	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad
3R	12300435	3R_12300435_SNP [dm3] 3R_16474713_SNP [dm6]	A	G	2.630e^-5	0.8	SYNONYMOUS_CODING Gyc-89Da	TF binding site mE1_TFBS_cad mE1_TFBS_sens
2R	6721985	2R_6721985_SNP [dm3] 2R_10834480_SNP [dm6]	A	C	2.638e^-5	0.8	UPSTREAM CG12344 INTRON CG12344
3R	9068911	3R_9068911_DEL [dm3] 3R_13243189_DEL [dm6]	TGCACC	G	2.656e^-5	0.8	INTRON Ace
2L	9654862	2L_9654862_SNP [dm3] 2L_9654862_SNP [dm6]	C	T	2.672e^-5	0.8	SYNONYMOUS_CODING Apoltp	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
3R	8677877	3R_8677877_SNP [dm3] 3R_12852155_SNP [dm6]	A	C	2.687e^-5	0.8	INTERGENIC
2R	16605931	2R_16605931_SNP [dm3] 2R_20718426_SNP [dm6]	G	A	2.696e^-5	0.8	INTRON dpr
X	12655726	X_12655726_SNP [dm3] X_12761693_SNP [dm6]	C	T	2.741e^-5	0.8	NON_SYNONYMOUS_CODING CG12717	TF binding site BDTNP1_TFBS_dl
3R	9156972	3R_9156972_SNP [dm3] 3R_13331250_SNP [dm6]	G	A	2.766e^-5	0.8	INTRON PK2-R2
3L	4434187	3L_4434187_INS [dm3] 3L_4434187_INS [dm6]	G	GAG	2.783e^-5	0.8	INTRON nAChRbeta1
2L	14065949	2L_14065949_SNP [dm3] 2L_14065949_SNP [dm6]	C	T	2.832e^-5	0.8	INTRON nAChRalpha5
2R	6722068	2R_6722068_SNP [dm3] 2R_10834563_SNP [dm6]	A	G	2.951e^-5	0.8	UPSTREAM CG12344 INTRON CG12344
3R	9169164	3R_9169164_SNP [dm3] 3R_13343442_SNP [dm6]	C	T	3.024e^-5	0.8	INTRON PK2-R1
2L	4393019	2L_4393019_SNP [dm3] 2L_4393019_SNP [dm6]	T	C	3.093e^-5	0.8	DOWNSTREAM Tps1 INTRON CG3652	TF binding site mE1_TFBS_cad mE1_TFBS_sens
3L	11872416	3L_11872416_SNP [dm3] 3L_11879316_SNP [dm6]	A	T	3.196e^-5	0.8	NON_SYNONYMOUS_CODING CG14128 INTRON CG44837
2R	13837428	2R_13837428_SNP [dm3] 2R_17949923_SNP [dm6]	A	T	3.258e^-5	0.8	INTERGENIC
2L	10553767	2L_10553767_SNP [dm3] 2L_10553767_SNP [dm6]	C	T	3.260e^-5	0.8	INTRON Trim9	TF binding site BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
2L	10554246	2L_10554246_SNP [dm3] 2L_10554246_SNP [dm6]	T	G	3.302e^-5	0.8	INTRON Trim9	TF binding site BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
3R	9292115	3R_9292115_SNP [dm3] 3R_13466393_SNP [dm6]	C	G	3.360e^-5	0.8	UPSTREAM CR17025 INTERGENIC	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_sens
3R	8687349	3R_8687349_SNP [dm3] 3R_12861627_SNP [dm6]	G	T	3.389e^-5	0.8	INTERGENIC
3L	15012617	3L_15012617_SNP [dm3] 3L_15019517_SNP [dm6]	A	G	3.399e^-5	0.8	INTRON Sytbeta	TF binding site mE1_TFBS_cad
2L	9762489	2L_9762489_SNP [dm3] 2L_9762489_SNP [dm6]	C	T	3.406e^-5	0.8	UTR_3_PRIME Taf11 UPSTREAM und DOWNSTREAM zf30C	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad
2L	9763247	2L_9763247_SNP [dm3] 2L_9763247_SNP [dm6]	T	G	3.436e^-5	0.8	UTR_5_PRIME Taf11 UPSTREAM und DOWNSTREAM zf30C	TF binding site BDTNP1_TFBS_dl mE1_TFBS_cad
3R	8684064	3R_8684064_SNP [dm3] 3R_12858342_SNP [dm6]	A	T	3.472e^-5	0.8	UPSTREAM CG10126 INTRON CG10126
X	15990838	X_15990838_SNP [dm3] X_16096805_SNP [dm6]	G	A	3.497e^-5	0.8	UPSTREAM CG42354 INTRON CG42354 & 1 other	TF binding site BDTNP1_TFBS_dl mE1_TFBS_bab1 mE1_TFBS_disco mE1_TFBS_GATAe mE1_TFBS_HSA mE1_TFBS_kn
2R	13060977	2R_13060977_SNP [dm3] 2R_17173472_SNP [dm6]	C	T	3.533e^-5	0.8	INTERGENIC
2L	12605980	2L_12605980_SNP [dm3] 2L_12605980_SNP [dm6]	C	T	3.583e^-5	0.8	INTRON nub
2L	9763278	2L_9763278_SNP [dm3] 2L_9763278_SNP [dm6]	T	A	3.631e^-5	0.8	UPSTREAM und & 1 other DOWNSTREAM zf30C INTERGENIC	TF binding site mE1_TFBS_cad
2L	9763280	2L_9763280_SNP [dm3] 2L_9763280_SNP [dm6]	A	C	3.657e^-5	0.8	UPSTREAM und & 1 other DOWNSTREAM zf30C INTERGENIC	TF binding site mE1_TFBS_cad
2R	1370622	2R_1370622_SNP [dm3] 2R_5483117_SNP [dm6]	T	G	3.659e^-5	0.8	INTRON CG30440	transposable element FlyBase
3R	18322716	3R_18322716_SNP [dm3] 3R_22496994_SNP [dm6]	C	T	3.716e^-5	0.8	UPSTREAM Octbeta1R INTERGENIC	TF binding site mE1_TFBS_inv
3L	13489463	3L_13489463_SNP [dm3] 3L_13496363_SNP [dm6]	T	C	3.751e^-5	0.8	INTRON Tgi
2L	9769368	2L_9769368_SNP [dm3] 2L_9769368_SNP [dm6]	A	G	3.768e^-5	0.8	SYNONYMOUS_CODING CG17633 DOWNSTREAM CG4017 INTRON ppk18	TF binding site mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_sens
2L	14327767	2L_14327767_SNP [dm3] 2L_14327767_SNP [dm6]	T	A	3.803e^-5	0.8	UTR_3_PRIME wb UPSTREAM ms_2_34Fe
3R	9169168	3R_9169168_SNP [dm3] 3R_13343446_SNP [dm6]	G	T	3.839e^-5	0.8	INTRON PK2-R1
2R	5108960	2R_5108960_SNP [dm3] 2R_9221455_SNP [dm6]	T	C	4.037e^-5	0.814	INTERGENIC	TF binding site BDTNP1_TFBS_twi
3R	25106441	3R_25106441_SNP [dm3] 3R_29280719_SNP [dm6]	G	A	4.037e^-5	0.814	INTERGENIC	regulatory region REDfly_CRMs
3R	9099346	3R_9099346_SNP [dm3] 3R_13273624_SNP [dm6]	A	G	4.157e^-5	0.814	INTERGENIC
3R	9297603	3R_9297603_SNP [dm3] 3R_13471881_SNP [dm6]	C	A	4.251e^-5	0.814	INTERGENIC
2R	18272754	2R_18272754_SNP [dm3] 2R_22385249_SNP [dm6]	C	A	4.263e^-5	0.814	INTRON CG13506
3R	9183475	3R_9183475_SNP [dm3] 3R_13357753_SNP [dm6]	G	C	4.437e^-5	0.814	INTERGENIC
X	12567283	X_12567283_SNP [dm3] X_12673250_SNP [dm6]	A	G	4.482e^-5	0.814	INTRON Tis11	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi
2L	723975	2L_723975_SNP [dm3] 2L_723975_SNP [dm6]	G	C	4.499e^-5	0.814	INTERGENIC
2R	19981343	2R_19981343_SNP [dm3] 2R_24093820_SNP [dm6]	C	T	4.549e^-5	0.814	SYNONYMOUS_CODING gek	TF binding site mE1_TFBS_cad
2L	4397283	2L_4397283_SNP [dm3] 2L_4397283_SNP [dm6]	T	A	4.573e^-5	0.814	SYNONYMOUS_CODING l_2_k05819

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GWAS results were computed on dm3 genome.

If you want to make an independent analysis with DGRP2 or PLINK2, you can find here prepared input files for this phenotype: DGRP2 results PLINK2 results

Full results

Phenotype distribution and association to known covariates

Shapiro-Wilk test of normality (p-value=6.631e^-1)
Null hypothesis is not rejected (p>0.05).
Interpretation: NORMAL distribution of this phenotype

We tested for association of this phenotype with 6 known covariates Huang et al., 2014 using both ANOVA and Kruskal-Wallis association tests.

ANOVA test

Covariate	p-value	Significance
In_2L_t	0.05437

Kruskal-Wallis test

Covariate	χ²	p-value	Significance
In_2L_t	6.3732	0.0413

PNG PDF

QQplot

PNG PDF

Manhattan plot

GWAS results

1624 significant hits at p-value < 0.001. The 1000 top results are displayed in the table below.

Variant impact HIGH MODERATE LOW MODIFIER

Show entries

Search:

Chromosome	Position	ID	Reference	Variant	p-value	FDR_BH	Transcript annotation	Binding site annotation
3L	6765765	3L_6765765_SNP [dm3] 3L_6772665_SNP [dm6]	C	T	1.746e^-7	0.249	INTERGENIC
3L	6766028	3L_6766028_SNP [dm3] 3L_6772928_SNP [dm6]	G	A	2.658e^-7	0.249	INTERGENIC
2L	1609677	2L_1609677_SNP [dm3] 2L_1609677_SNP [dm6]	G	T	1.501e^-6	0.722	INTRON CG31935	TF binding site mE1_TFBS_cad
3R	18521998	3R_18521998_SNP [dm3] 3R_22696276_SNP [dm6]	G	A	1.539e^-6	0.722	SYNONYMOUS_CODING cd	TF binding site mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_sens
2L	5809179	2L_5809179_SNP [dm3] 2L_5809179_SNP [dm6]	G	A	3.628e^-6	0.947	UPSTREAM CR44575 DOWNSTREAM CG11034 INTERGENIC
2R	8844260	2R_8844260_SNP [dm3] 2R_12956755_SNP [dm6]	A	C	4.330e^-6	0.947	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_ttk
2L	7923089	2L_7923089_SNP [dm3] 2L_7923089_SNP [dm6]	T	C	4.624e^-6	0.947	INTRON Snoo
2R	6757322	2R_6757322_SNP [dm3] 2R_10869817_SNP [dm6]	C	T	4.802e^-6	0.947	INTRON CG30015
2R	1129277	2R_1129277_SNP [dm3] 2R_5241772_SNP [dm6]	T	A	4.841e^-6	0.947	INTRON Nipped-A	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
2R	8844257	2R_8844257_SNP [dm3] 2R_12956752_SNP [dm6]	C	A	5.506e^-6	0.947	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_ttk
3R	20926879	3R_20926879_SNP [dm3] 3R_25101157_SNP [dm6]	C	A	5.844e^-6	0.947	NON_SYNONYMOUS_CODING CG33095 UTR_3_PRIME CG33096	TF binding site mE1_TFBS_sens
2R	9772188	2R_9772188_SNP [dm3] 2R_13884683_SNP [dm6]	G	A	6.057e^-6	0.947	SYNONYMOUS_CODING shot INTRON shot	TF binding site mE1_TFBS_cad mE1_TFBS_chinmo
2L	9251457	2L_9251457_SNP [dm3] 2L_9251457_SNP [dm6]	C	A	7.761e^-6	0.998	UPSTREAM aust DOWNSTREAM borr EXON CR43734
2L	7923109	2L_7923109_SNP [dm3] 2L_7923109_SNP [dm6]	C	T	8.229e^-6	0.998	INTRON Snoo
2R	12345809	2R_12345809_SNP [dm3] 2R_16458304_SNP [dm6]	T	C	8.548e^-6	0.998	INTERGENIC
2L	3993370	2L_3993370_SNP [dm3] 2L_3993370_SNP [dm6]	G	T	1.136e^-5	0.998	INTERGENIC
3R	12676548	3R_12676548_DEL [dm3] 3R_16850826_DEL [dm6]	GG	G	1.289e^-5	0.998	INTRON iab-8 EXON iab-4	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_prd mE1_TFBS_cad mE1_TFBS_Trl
2L	9715710	2L_9715710_SNP [dm3] 2L_9715710_SNP [dm6]	T	C	1.296e^-5	0.998	UTR_3_PRIME Nckx30C DOWNSTREAM Nckx30C	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
3R	26072736	3R_26072736_SNP [dm3] 3R_30247014_SNP [dm6]	G	T	1.338e^-5	0.998	UPSTREAM CG9733 DOWNSTREAM tRNA:CR31383 INTERGENIC
2L	19617332	2L_19617332_SNP [dm3] 2L_19617332_SNP [dm6]	A	C	1.341e^-5	0.998	INTRON Lar
2L	12504432	2L_12504432_SNP [dm3] 2L_12504432_SNP [dm6]	A	G	1.541e^-5	0.998	UTR_5_PRIME bun INTRON bun	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_hb BDTNP1_TFBS_Med mE1_TFBS_D mE1_TFBS_HSA
X	6469945	X_6469945_SNP [dm3] X_6575912_SNP [dm6]	G	A	1.615e^-5	0.998	INTRON CG34417
2R	8844254	2R_8844254_SNP [dm3] 2R_12956749_SNP [dm6]	G	T	1.618e^-5	0.998	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_ttk
2L	12568385	2L_12568385_SNP [dm3] 2L_12568385_SNP [dm6]	G	A	1.748e^-5	0.998	INTERGENIC
2R	6969944	2R_6969944_SNP [dm3] 2R_11082439_SNP [dm6]	G	A	1.761e^-5	0.998	INTRON luna
2R	4853327	2R_4853327_SNP [dm3] 2R_8965822_SNP [dm6]	T	G	1.903e^-5	0.998	INTRON CG8216
2L	5690242	2L_5690242_SNP [dm3] 2L_5690242_SNP [dm6]	G	A	1.986e^-5	0.998	UPSTREAM CR44819 DOWNSTREAM CR44820 INTERGENIC
2R	8844056	2R_8844056_SNP [dm3] 2R_12956551_SNP [dm6]	A	T	1.996e^-5	0.998	DOWNSTREAM CG13321 INTERGENIC	silencer mE1_HDAC_PRE TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA mE1_TFBS_Trl
3L	16981203	3L_16981203_SNP [dm3] 3L_16988103_SNP [dm6]	A	T	2.128e^-5	0.998	INTRON Exn
3R	2720642	3R_2720642_SNP [dm3] 3R_6894920_SNP [dm6]	T	C	2.270e^-5	0.998	DOWNSTREAM CR44932 INTERGENIC	regulatory region FlyBase REDfly_CRMs
X	3457239	X_3457239_SNP [dm3] X_3563206_SNP [dm6]	A	G	2.293e^-5	0.998	INTRON CG32791 & 1 other
3R	17690116	3R_17690116_SNP [dm3] 3R_21864394_SNP [dm6]	T	G	2.356e^-5	0.998	UPSTREAM lsn INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi
2L	4394391	2L_4394391_SNP [dm3] 2L_4394391_SNP [dm6]	T	A	2.359e^-5	0.998	SYNONYMOUS_CODING l_2_k05819 UPSTREAM CG3652	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_sens mE1_TFBS_Ubx
X	16032413	X_16032413_SNP [dm3] X_16138380_SNP [dm6]	T	C	2.443e^-5	0.998	INTRON disco-r	TF binding site BDTNP1_TFBS_da mE1_TFBS_HSA
X	7199131	X_7199131_INS [dm3] X_7305098_INS [dm6]	T	TGTGTGT	2.496e^-5	0.998	INTRON CR44357 & 1 other	TF binding site BDTNP1_TFBS_dl
3R	15982035	3R_15982035_SNP [dm3] 3R_20156313_SNP [dm6]	C	T	2.528e^-5	0.998	INTERGENIC
2R	14137154	2R_14137154_SNP [dm3] 2R_18249649_SNP [dm6]	A	T	2.581e^-5	0.998	INTERGENIC	TF binding site mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_inv
2R	1236974	2R_1236974_SNP [dm3] 2R_5349469_SNP [dm6]	T	C	2.619e^-5	0.998	INTERGENIC	transposable element FlyBase
2R	8844052	2R_8844052_SNP [dm3] 2R_12956547_SNP [dm6]	A	T	2.649e^-5	0.998	DOWNSTREAM CG13321 INTERGENIC	silencer mE1_HDAC_PRE TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA mE1_TFBS_Trl
2R	6777934	2R_6777934_SNP [dm3] 2R_10890429_SNP [dm6]	C	T	2.669e^-5	0.998	SYNONYMOUS_CODING CG30020	TF binding site mE1_TFBS_inv
2R	8844246	2R_8844246_SNP [dm3] 2R_12956741_SNP [dm6]	A	C	2.755e^-5	0.998	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA mE1_TFBS_ttk
2L	5812385	2L_5812385_SNP [dm3] 2L_5812385_SNP [dm6]	C	T	2.796e^-5	0.998	DOWNSTREAM CG43307 INTERGENIC
X	21444190	X_21444190_INS [dm3] X_21573163_INS [dm6]	A	AA	2.853e^-5	0.998	INTERGENIC	TF binding site mE1_TFBS_HSA
2L	2618930	2L_2618930_SNP [dm3] 2L_2618930_SNP [dm6]	T	A	2.920e^-5	0.998	INTERGENIC
2L	8117741	2L_8117741_SNP [dm3] 2L_8117741_SNP [dm6]	C	T	2.920e^-5	0.998	INTRON mon2
2R	2743219	2R_2743219_SNP [dm3] 2R_6855714_SNP [dm6]	C	T	2.954e^-5	0.998	INTERGENIC
3L	10230267	3L_10230267_SNP [dm3] 3L_10237167_SNP [dm6]	G	C	2.989e^-5	0.998	DOWNSTREAM CR44542 INTERGENIC
3R	21590671	3R_21590671_SNP [dm3] 3R_25764949_SNP [dm6]	G	A	3.048e^-5	0.998	INTERGENIC	TF binding site mE1_TFBS_inv
2R	8844266	2R_8844266_SNP [dm3] 2R_12956761_SNP [dm6]	G	C	3.051e^-5	0.998	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_ttk
2R	8844269	2R_8844269_SNP [dm3] 2R_12956764_SNP [dm6]	C	A	3.051e^-5	0.998	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_ttk
2R	8844270	2R_8844270_SNP [dm3] 2R_12956765_SNP [dm6]	T	A	3.080e^-5	0.998	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_ttk
3R	19237680	3R_19237680_SNP [dm3] 3R_23411958_SNP [dm6]	G	A	3.118e^-5	0.998	SYNONYMOUS_CODING CG4374	TF binding site mE1_TFBS_cad mE1_TFBS_chinmo
2L	4120682	2L_4120682_SNP [dm3] 2L_4120682_SNP [dm6]	A	G	3.136e^-5	0.998	NON_SYNONYMOUS_CODING Sr-CIII
X	16344746	X_16344746_SNP [dm3] X_16450713_SNP [dm6]	A	T	3.253e^-5	0.998	INTRON Rbp2
3R	21590657	3R_21590657_SNP [dm3] 3R_25764935_SNP [dm6]	A	G	3.258e^-5	0.998	INTERGENIC	TF binding site mE1_TFBS_inv
3L	1234268	3L_1234268_SNP [dm3] 3L_1234268_SNP [dm6]	C	T	3.338e^-5	0.998	SYNONYMOUS_CODING CG33966 DOWNSTREAM CG33965
2R	1080219	2R_1080219_SNP [dm3] 2R_5192714_SNP [dm6]	G	A	3.383e^-5	0.998	INTRON Nipped-A
2R	6970027	2R_6970027_SNP [dm3] 2R_11082522_SNP [dm6]	A	C	3.432e^-5	0.998	INTRON luna
2R	8844262	2R_8844262_INS [dm3] 2R_12956757_INS [dm6]	A	ACTGGATC	3.457e^-5	0.998	INTERGENIC	TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_ttk
2L	4120701	2L_4120701_SNP [dm3] 2L_4120701_SNP [dm6]	G	C	3.635e^-5	0.998	NON_SYNONYMOUS_CODING Sr-CIII
2L	5676774	2L_5676774_SNP [dm3] 2L_5676774_SNP [dm6]	G	A	3.642e^-5	0.998	INTERGENIC
3L	10230195	3L_10230195_SNP [dm3] 3L_10237095_SNP [dm6]	C	A	3.666e^-5	0.998	DOWNSTREAM CR44542 INTERGENIC
3R	4692377	3R_4692377_SNP [dm3] 3R_8866655_SNP [dm6]	C	T	3.747e^-5	0.998	INTRON pyd
3R	24479788	3R_24479788_SNP [dm3] 3R_28654066_SNP [dm6]	T	G	3.810e^-5	0.998	INTERGENIC
3L	7144064	3L_7144064_SNP [dm3] 3L_7150964_SNP [dm6]	A	C	3.829e^-5	0.998	INTRON corn	TF binding site BDTNP1_TFBS_prd BDTNP1_TFBS_twi mE1_TFBS_HSA
3R	20335715	3R_20335715_DEL [dm3] 3R_24509993_DEL [dm6]	AA	A	3.934e^-5	0.998	INTRON nAChRbeta2
2L	4095701	2L_4095701_SNP [dm3] 2L_4095701_SNP [dm6]	C	A	4.080e^-5	0.998	INTRON ed	TF binding site BDTNP1_TFBS_twi
2L	9289256	2L_9289256_SNP [dm3] 2L_9289256_SNP [dm6]	G	A	4.101e^-5	0.998	INTRON Ggamma30A
3L	3878473	3L_3878473_SNP [dm3] 3L_3878473_SNP [dm6]	G	A	4.110e^-5	0.998	INTERGENIC	silencer mE1_HDAC_PRE TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_twi BDTNP1_TFBS_z mE1_TFBS_cad mE1_TFBS_HSA
2R	9368277	2R_9368277_SNP [dm3] 2R_13480772_SNP [dm6]	T	C	4.190e^-5	0.998	INTRON arr
2R	8844063	2R_8844063_SNP [dm3] 2R_12956558_SNP [dm6]	A	G	4.264e^-5	0.998	DOWNSTREAM CG13321 INTERGENIC	silencer mE1_HDAC_PRE TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA mE1_TFBS_Trl
3L	5140297	3L_5140297_SNP [dm3] 3L_5147197_SNP [dm6]	T	C	4.290e^-5	0.998	SYNONYMOUS_CODING Aats-ala-m	TF binding site mE1_TFBS_chinmo mE1_TFBS_sens
3R	19232812	3R_19232812_SNP [dm3] 3R_23407090_SNP [dm6]	C	T	4.334e^-5	0.998	SYNONYMOUS_CODING Ir94e	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
3R	19232827	3R_19232827_SNP [dm3] 3R_23407105_SNP [dm6]	C	A	4.334e^-5	0.998	SYNONYMOUS_CODING Ir94e	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
2L	9289273	2L_9289273_SNP [dm3] 2L_9289273_SNP [dm6]	C	G	4.359e^-5	0.998	INTRON Ggamma30A
3L	14526017	3L_14526017_SNP [dm3] 3L_14532917_SNP [dm6]	C	T	4.363e^-5	0.998	INTRON bbg
2R	5231896	2R_5231896_SNP [dm3] 2R_9344391_SNP [dm6]	T	C	4.399e^-5	0.998	UPSTREAM Or45a INTRON CG13954 & 1 other
3R	21590666	3R_21590666_SNP [dm3] 3R_25764944_SNP [dm6]	T	G	4.664e^-5	0.998	INTERGENIC	TF binding site mE1_TFBS_inv
2L	8118325	2L_8118325_SNP [dm3] 2L_8118325_SNP [dm6]	C	T	4.829e^-5	0.998	SYNONYMOUS_CODING mon2	TF binding site mE1_TFBS_HSA mE1_TFBS_sens
2R	8844138	2R_8844138_SNP [dm3] 2R_12956633_SNP [dm6]	C	T	4.893e^-5	0.998	DOWNSTREAM CG13321 INTERGENIC	silencer mE1_HDAC_PRE TF binding site BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_Med mE1_TFBS_HSA
2L	8117890	2L_8117890_SNP [dm3] 2L_8117890_SNP [dm6]	T	A	4.973e^-5	0.998	INTRON mon2
2R	2087287	2R_2087287_SNP [dm3] 2R_6199782_SNP [dm6]	A	G	5.108e^-5	0.998	INTERGENIC	TF binding site BDTNP1_TFBS_dl BDTNP1_TFBS_Med BDTNP1_TFBS_sna BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_HSA
3R	7089376	3R_7089376_SNP [dm3] 3R_11263654_SNP [dm6]	G	T	5.165e^-5	0.998	INTERGENIC
2R	5125795	2R_5125795_SNP [dm3] 2R_9238290_SNP [dm6]	T	A	5.207e^-5	0.998	INTRON hig & 1 other
3R	13321061	3R_13321061_SNP [dm3] 3R_17495339_SNP [dm6]	A	G	5.260e^-5	0.998	INTRON Dscam3
2R	6969943	2R_6969943_SNP [dm3] 2R_11082438_SNP [dm6]	A	T	5.267e^-5	0.998	INTRON luna
2L	9715726	2L_9715726_SNP [dm3] 2L_9715726_SNP [dm6]	G	A	5.336e^-5	0.998	UTR_3_PRIME Nckx30C DOWNSTREAM Nckx30C	TF binding site BDTNP1_TFBS_dl mE1_TFBS_HSA
3R	8554346	3R_8554346_SNP [dm3] 3R_12728624_SNP [dm6]	G	A	5.347e^-5	0.998	DOWNSTREAM CR44231 INTERGENIC
2R	9450758	2R_9450758_SNP [dm3] 2R_13563253_SNP [dm6]	C	T	5.553e^-5	0.998	INTERGENIC	TF binding site BDTNP1_TFBS_bcd BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_gt BDTNP1_TFBS_hb BDTNP1_TFBS_kni BDTNP1_TFBS_prd BDTNP1_TFBS_shn BDTNP1_TFBS_sna BDTNP1_TFBS_tll BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_cnc mE1_TFBS_D mE1_TFBS_disco mE1_TFBS_eve mE1_TFBS_hkb mE1_TFBS_HSA mE1_TFBS_inv mE1_TFBS_Kr mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
2L	12568627	2L_12568627_SNP [dm3] 2L_12568627_SNP [dm6]	G	C	5.688e^-5	0.998	INTERGENIC
2R	6104599	2R_6104599_SNP [dm3] 2R_10217094_SNP [dm6]	G	A	5.774e^-5	0.998	INTRON Hr46 & 1 other
X	6470330	X_6470330_SNP [dm3] X_6576297_SNP [dm6]	A	C	5.807e^-5	0.998	INTRON CG34417
3L	5140526	3L_5140526_SNP [dm3] 3L_5147426_SNP [dm6]	C	A	5.866e^-5	0.998	INTRON Aats-ala-m	TF binding site mE1_TFBS_chinmo mE1_TFBS_sens
2L	10751601	2L_10751601_SNP [dm3] 2L_10751601_SNP [dm6]	T	A	5.917e^-5	0.998	INTRON CG17124	TF binding site mE1_TFBS_cad
2L	4861523	2L_4861523_SNP [dm3] 2L_4861523_SNP [dm6]	C	A	5.946e^-5	0.998	INTRON pog
X	19994545	X_19994545_SNP [dm3] X_20100512_SNP [dm6]	C	T	6.044e^-5	0.998	INTERGENIC	transposable element FlyBase
3L	5140192	3L_5140192_SNP [dm3] 3L_5147092_SNP [dm6]	C	T	6.079e^-5	0.998	INTRON Aats-ala-m	TF binding site BDTNP1_TFBS_hb mE1_TFBS_chinmo mE1_TFBS_sens
2R	9450556	2R_9450556_SNP [dm3] 2R_13563051_SNP [dm6]	C	T	6.171e^-5	0.998	INTERGENIC	TF binding site BDTNP1_TFBS_bcd BDTNP1_TFBS_da BDTNP1_TFBS_dl BDTNP1_TFBS_gt BDTNP1_TFBS_hb BDTNP1_TFBS_kni BDTNP1_TFBS_Med BDTNP1_TFBS_prd BDTNP1_TFBS_shn BDTNP1_TFBS_sna BDTNP1_TFBS_tll BDTNP1_TFBS_twi mE1_TFBS_cad mE1_TFBS_cnc mE1_TFBS_D mE1_TFBS_disco mE1_TFBS_hkb mE1_TFBS_HSA mE1_TFBS_inv mE1_TFBS_Kr mE1_TFBS_sens mE1_TFBS_Trl mE1_TFBS_zfh1
2R	1080299	2R_1080299_DEL [dm3] 2R_5192794_DEL [dm6]	GTTCG	G	6.381e^-5	0.998	INTRON Nipped-A
2L	8117743	2L_8117743_DEL [dm3] 2L_8117743_DEL [dm6]	TTG	C	6.424e^-5	0.998	INTRON mon2

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By genomic position
Variant impact
Gene name

mn_Resp_Hexanal phenotype

Phenotype distribution and association to known covariates

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Manhattan plot

GWAS results

Phenotype distribution and association to known covariates

QQplot

Manhattan plot

GWAS results